ABCs Report: Haemophilus influenzae, 2015
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March 23, 2017: Content on this page kept for historical reasons.
Active Bacterial Core Surveillance (ABCs): Emerging Infections Program Network
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¶Surveillance Note
Missing race (n=61) data were multiply imputed using sequential regression imputation methods.
ABCs Areas
California (3 county San Francisco Bay area); Colorado (5 county Denver area); Connecticut; Georgia; Maryland; Minnesota; New Mexico; New York (15 county Rochester and Albany areas); Oregon; Tennessee (20 urban counties)
ABCs Population
The surveillance areas represent 43,912,997 persons.
Source: National Center for Health Statistics bridged-race vintage 2015 postcensal file
ABCs Case Definition
Invasive Haemophilus influenzae (Hi) disease: isolation of Hi from normally sterile site in a resident of a surveillance area in 2015.
ABCs Methodology
ABCs personnel routinely contacted all microbiology laboratories serving acute care hospitals in their area to identify cases. Standardized case report forms that include information on demographic characteristics, clinical syndrome, and outcome of illness were completed for each identified case. Serotyping was done on Hi isolates at CDC and state laboratories. Regular laboratory audits assessed completeness of active surveillance and detected additional cases.
All rates of invasive Hi disease were calculated using population estimates for 2015 from the bridged-race vintage 2015 postcensal file. For national estimates, race and age specific rates of disease were applied from the aggregate surveillance areas to the race and age specific distribution of the 2015 U.S. population. Cases with missing data, excluding ethnicity, were multiply imputed using sequential regression imputation methods.¶
Reported ABCs Profiles
Race | No. | (Rate*) |
---|---|---|
White | 623 | (1.9) |
Black | 150 | (1.9) |
Other | 49 | (1.4) |
Total | 822 | (1.9) |
* Per 100,000 population for ABCs areas
Syndrome | Cases No. (%*) |
Deaths No. (Rate†) |
---|---|---|
Meningitis | 56 (6.8) | 4 (7.1) |
Bacteremia without focus | 193 (23.5) | 35 (18.1) |
Pneumonia with bacteremia | 472 (57.4) | 81 (17.2) |
* Percent of cases
† Deaths per 100 cases with known outcome
Age (years) | Serotype b No. (Rate*) |
Serotype Non‑b No. (Rate*) |
Serotype Non‑Type† No. (Rate*) |
Serotype Unknown No. (Rate*) |
---|---|---|---|---|
< 1 | 1 (0.19) | 15 (2.82) | 26 (4.88) | 5 (0.94) |
1 | 0 (0.00) | 5 (0.94) | 7 (1.32) | 1 (0.19) |
2-4 | 1 (0.06) | 12 (0.74) | 8 (0.50) | 1 (0.06) |
5-17 | 1 (0.01) | 9 (0.12) | 16 (0.22) | 6 (0.08) |
18-34 | 1 (0.01) | 7 (0.07) | 33 (0.32) | 4 (0.04) |
35-49 | 1 (0.01) | 10 (0.12) | 51 (0.59) | 10 (0.12) |
50-64 | 2 (0.02) | 57 (0.65) | 111 (1.27) | 21 (0.24) |
65-74 | 1 (0.03) | 35 (0.95) | 100 (2.72) | 16 (0.44) |
75-84 | 0 (0.00) | 23 (1.30) | 100 (5.67) | 12 (0.68) |
≥ 85 | 0 (0.00) | 11 (1.36) | 92 (11.37) | 10 (1.24) |
Total | 8 (0.02) | 184 (0.42) | 544 (1.24) | 86 (0.20) |
* Per 100,000 population for ABCs areas
† Non-typeable isolates
National Estimates for Invasive Disease
Cases: 6,100 (1.90/100,000)
Deaths: 1,015 (0.32/100,000)
Healthy People 2020 Update
Invasive Haemophilus influenzae type b disease
Objective: Decrease the incidence of invasive Haemophilus influenzae type b disease to 0.27 cases per 100,000 persons less than 5 years of age
Age (year) | 2020 Objective | 2015 Rate* |
---|---|---|
< 5 | 0.27/100,000 | 0.07/100,000 |
* Per 100,000 U.S. population < 5 years
Citation
Centers for Disease Control and Prevention. 2015. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Haemophilus influenza 2015.
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