ABCs Report: Group B Streptococcus, 2015

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Active Bacterial Core Surveillance (ABCs): Emerging Infections Program Network

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^¶Surveillance Note

Missing race (n=262) data were multiply imputed using sequential regression imputation methods.

ABCs Areas

California (3 county San Francisco Bay area); Colorado (5 county Denver area); Connecticut (children < 1 year); Georgia (20 county); Maryland; Minnesota; New Mexico; New York (15 county Rochester and Albany areas); Oregon (3 county Portland area); Tennessee (20 counties)

ABCs Population

The surveillance areas represent 33,415,379 persons and 437,266 live births.

Source: National Center for Health Statistics bridged race vintage 2015 postcensal file and 2013 state vital records

ABCs Case Definition

Invasive group B streptococcal disease: isolation of Group B Streptococcus from a normally sterile site in a resident of a surveillance area in 2015. Early-onset cases occur at < 7 days of age and late-onset occur between 7 and 89 days of age.

ABCs Methodology

ABCs personnel routinely contacted all microbiology laboratories serving acute care hospitals in their area to identify cases. Standardized case report forms that include information on demographic characteristics, clinical syndrome, and outcome of illness were completed for each identified case. Regular laboratory audits assessed completeness of active surveillance and detected additional cases.

Rates of early-onset and late-onset group B streptococcal disease were calculated using live birth estimates for 2013. All other rates were calculated using population estimates for 2015 from the bridged-race vintage 2015 postcensal file. For national estimates of cases, race- and age-specific rates of disease were applied from the aggregate surveillance area to the age and racial distribution of the 2015 U.S. population and to the 2013 live birth estimates for early-onset and late-onset disease. Cases with missing data, excluding ethnicity, were multiply imputed using sequential regression imputation methods.^¶

Reported ABCs Profiles

Race	No.	(Rate^*)
White	2,074	(8.6)
Black	708	(11.5)
Other	174	(5.5)

^* Per 100,000 population for ABCs areas

Ethnicity	No.	(Rate^*)
Hispanic	254	(5.7)
Non-Hispanic	2,155	—
Unknown	547	—

^* Per 100,000 population for ABCs areas

Age (years)	Cases No. (Rate^*)	Deaths No. (Rate^*)
< 1	275 (61.3)	20 (4.46)
1	4 (1.0)	0 (0.00)
2-4	1 (0.1)	1 (0.08)
5-17	11 (0.2)	1 (0.02)
18-34	176 (2.2)	3 (0.04)
35-49	392 (5.9)	12 (0.18)
50-64	919 (14.0)	56 (0.85)
65-74	532 (19.8)	29 (1.08)
75-84	394 (30.9)	31 (2.43)
≥ 85	252 (42.6)	28 (4.73)
Total	2,956 (8.9)	181 (0.54)

^* Per 100,000 population for ABCs areas

Race	Early-Onset No. (Rate^*)	Late-Onset No. (Rate^*)
White	45 (0.15)	76 (0.25)
Black	53 (0.57)	63 (0.68)
Other	4 (0.09)	11 (0.25)
Total	102 (0.23)	150 (0.34)

^* Per 1,000 live birth for ABCs areas

National Estimates of Invasive Disease

Early Onset Cases: 840 (0.21/1,000 live births)
Late Onset Cases: 1,265 (0.32/1,000 live births)
Total Cases: 28,550 (8.9/100,000 population)
Deaths: 1,770 (0.55/100,000 population)

Healthy People 2020 Update

Early-Onset Disease

Objective: Decrease the incidence of invasive early-onset group B streptococcal disease to 0.25 cases per 1,000 live births.

Race	2020 Objective	2015 Rate*
White	0.25/1,000	0.15/1,000
Black	0.25/1,000	0.57/1,000
Other	0.25/1,000	0.09/1,000
Total	0.25/1,000	0.23/1,000

^* Per 1,000 U.S. live births

Citation

Centers for Disease Control and Prevention. 2015. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group B Streptococcus, 2015.

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