Sodium aurothiosulfate

Sodium aurothiosulfate is the inorganic compound with the formula Na3Au(S2O3)2·2H2O. This salt contains an anionic linear coordination complex of gold(I) bound to two thiosulfate ligands.[1][2] Like several other gold compounds, this species is used as an antirheumatic.[3] The first placebo-controlled trial was probably conducted in 1931, when sanocrysin was compared with distilled water for the treatment of tuberculosis.[4]

Sodium aurothiosulfate
Clinical data
Routes of
administration		Intramuscular injection
ATC code
Identifiers
CAS Number
PubChem CID
Chemical and physical data
FormulaAuNa3O6S4
Molar mass332.08452 g/mol g·mol−1
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References
  1. Baggio, R. F.; Baggio, S. (1973). "Crystal and molecular structure of trisodium dithiosulphate aurate(I), dihydrate, Na3[Au(S2O3)2],2H2O". Journal of Inorganic and Nuclear Chemistry. 35 (9): 3191–3200. doi:10.1016/0022-1902(73)80019-3.
  2. Tobön-Zapata, G.; Etcheverry, S. B.; Baran, E. J. (1997). "Vibrational spectrum of Sanocrysin". Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 53 (2): 183–188. doi:10.1016/S1386-1425(97)83024-7.
  3. Shaw, III, C. F. (1999). "Gold-Based Therapeutic Agents". Chemical Reviews. 99 (9): 2589–600. doi:10.1021/cr980431o. PMID 11749494.
  4. Emanuel, E. J.; Crouch, R. A.; Arras, J. D.; Moreno, J. D.; Grady, C., eds. (2003). Ethical and regulatory aspects of clinical research: readings and commentary. Johns Hopkins University Press. p. 140. ISBN 978-0801878138.

Source of Chemical Formula: http://medical.merriam-webster.com/medical/gold%20sodium%20thiomalate


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