Optic nerve glioma

Optic nerve glioma (or optic glioma), a form of glioma which affects the optic nerve, is often one of the central nervous system manifestations of neurofibromatosis 1.[1][2]

Optic nerve glioma
Magnetic resonance image of a large retrobulbar optic nerve tumor causing massive proptosis
SpecialtyOncology 

Optic gliomas are usually pilocytic tumors, and can involve the optic nerve or optic chiasm.[3] Optic gliomas are usually associated with neurofibromatosis type 1 in 30% of patients.[3]

Diagnosis

Treatment

While radiation or chemotherapy may be helpful, treatment is often not necessary.[3] Optical gliomas often cannot be surgically resected. If no visual symptoms wait 6 months and then in 6 months only treat if there are symptoms (visual loss, eye pain), otherwise do not treat.[3]

Prognosis

Optic gliomas often have a shifting clinical course, with sporadic periods of vision loss separated by long periods of visual stability.[3] Optic gliomas rarely spontaneously regress.[3]

References
  1. Huson, Susan Mary; Hughes, Richard Anthony Cranmer (1994). The neurofibromatoses: a pathogenetic and clinical overview. London: Chapman & Hall. 1.3.2:9. ISBN 0-412-38920-7.
  2. Skelley, Tao Le, Vikas Bhushan, Nathan William (2012-03-12). First aid for the USMLE step 2 CK (8th ed.). New York: McGraw-Hill Medical. ISBN 978-0-07-176137-6.
  3. Goldman, Lee. Goldman's Cecil Medicine (24th ed.). Philadelphia: Elsevier Saunders. p. 1251. ISBN 1437727883.
Classification
External resources


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