Hyper-IgM syndrome type 4

Classification	D ICD-10: D80.5; ICD-9-CM: 279.05; OMIM: 608184; MeSH: D053306;
External resources	eMedicine: ped/2457;

Hyper-IgM syndrome type 4
	Immunoglobulin M
Specialty	Hematology

Hyper-IgM syndrome type 4 is a form of Hyper IgM syndrome which is a defect in class switch recombination downstream of the AICDA gene that does not impair somatic hypermutation.[1]

References

Lougaris V, Badolato R, Ferrari S, Plebani A (2005). "Hyper immunoglobulin M syndrome due to CD40 deficiency: clinical, molecular, and immunological features". Immunol. Rev. 203: 48–66. doi:10.1111/j.0105-2896.2005.00229.x. PMID 15661021.

External links

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[1] Lougaris V, Badolato R, Ferrari S, Plebani A (2005). "Hyper immunoglobulin M syndrome due to CD40 deficiency: clinical, molecular, and immunological features". Immunol. Rev. 203: 48–66. doi:10.1111/j.0105-2896.2005.00229.x. PMID 15661021.

Classification	D ICD-10: D80.5 ICD-9-CM: 279.05 OMIM: 608184 MeSH: D053306
External resources	eMedicine: ped/2457