Fenticlor
Fenticlor (also spelled fentichlor) is an antibacterial and antifungal agent for topical use. It is an antimicrobial agent. It is also used in veterinary medicine.
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Routes of administration | topical |
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ECHA InfoCard | 100.002.336 ![]() |
Chemical and physical data | |
Formula | C12H8Cl2O2S |
Molar mass | 287.16 g/mol g·mol−1 |
Melting point | 174 °C (345 °F) |
Synthesis
It is prepared by the AlCl3-catalyzed reaction of 4-chlorophenol with sulfur dichloride.[1] It can also be prepared by chlorination of bis[2-hydroxyphenyl]sulfide.[2][3]
Safety
LD50 (rats, oral) = 3250 mg/kg.[1] It may cause photosensitivity [4]
References
- Helmut Fiege; Heinz-Werner Voges; Toshikazu Hamamoto; Sumio Umemura; Tadao Iwata; Hisaya Miki; Yasuhiro Fujita; Hans-Josef Buysch; Dorothea Garbe (2007). "Phenol Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a19_313.
- Muth, DE 568944 (1931 to I. G. Farben).
- Dunning, F.; Dunning, B.; Drake, W. E. (1931). "Preparation and Bacteriological Study of Some Symmetrical Organic Sulfides". Journal of the American Chemical Society. 53 (9): 3466. doi:10.1021/ja01360a035.
- Burry JN (June 1974). "Letter: Fenticlor, actinic reticuloid, and antihistamines". Br Med J. 2 (5918): 556–7. doi:10.1136/bmj.2.5918.556-c. PMC 1610938. PMID 4152080.
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