We need you! Join our contributor community and become a WikEM editor through our open and transparent promotion process.
Physostigmine
From WikEM
Contents
General
- Type: acetylcholinesterase inhibitor
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Anticholinergic toxicity
- 0.5-2mg IV over 5min
Pediatric Dosing
- .02mg/kg repeat every 5-10 minutes until adequate response, max of 2mg
- no faster than .5mg/min
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
- Side effects: bradycardia, dysrhythmias, cholinergic excess
- Always have atropine at the bedside for bradycardia or cholinergic excess
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
- Onset of action: 15-20min
See Also
References
Authors
Ross Donaldson, Rafael Caban, Daniel Ostermayer, Neil Young, Claire
