Atropine

Adult Dosing

• Loading dose = 0.5mg rapid IV bolus q3-5min (max = 0.04 milligram/kg)
• May be given IM, IO, SC

Indications

• Symptomatic sinus or AV nodal bradycardia

Mechanism of Action

• Parasympatholytic
  • Increases sinus/AV conduction

Adverse Drug Reactionss

• Increased O2 consumption
• If given slowly (or <0.5mg) may lead to paradoxical bradycardia

Kinetics

• Onset of action = 2-4min
• Duration of action = 5hr

See Also

• Antiarrhythmics
• Critical care quick reference
• Anticholinergic toxicity

Authors

Ross Donaldson, Neil Young, Daniel Ostermayer