Conjunctivitis

Doxycycline 100mg BID for 7 days OR
Azithromycin 1g (20mg/kg) PO one time dose
Newborn Treatment: Azithromycin 20mg/kg PO once daily x 3 days
- Disease manifests 5 days post-birth to 2 weeks (late onset)

Dual treatment for Chlamydia is recommended with azithromycin
Ceftriaxone 1g IM one dose PLUS
Azithromycin 1g PO one dose
Newborn Treatment:
- Prophylaxis: Erythromycin ophthalmic 0.5% x1
- Disease manifests 1st 5 days post delivery (early onset)
- Treatment Ceftriaxone 25-50mg IV or IM, max 125mg

These options do not cover gonococcal or chlamydial infections

Polymyxin B/Trimethoprim (Polytrim) 2 drops every 6 hours for 7 days OR
Erythromycin applied to the conjunctiva q6hrs fir 7 days OR
Levofloxacin 0.5% ophthalmic solution 1-2 drops every 2 hours for 2 days THEN every 6 hours for 5 days OR
Moxifloxacin 0.5% ophthalmic 1-2 drops every 2 hours for 2 days THEN every 6 hours for 5 days OR
Gatifloxacin 0.5% ophthalmic solution 1-2 drops every 2 hours for 2 days THEN 1 drop every 6 hours for 5 days OR
Azithromycin 1% ophthalmic solution 1 drop BID for 2 days THEN 1 drop daily for 5 days

Corneal Abrasion

Antibiotics should cover pseudomonas and favor 3rd or 4th generation fluoroquinolones

Levofloxacin 0.5% solution 2 drops ever 2 hours for 2 days THEN q6hrs for 5 days OR
Moxifloxacin 0.5% solution 2 drops every 2 hours for 2 days THEN q6hrs for 5 days OR
Tobramycin 0.3% solution 2 drops q6hrs for 5 days OR
Gatifloxacin 0.5% solution 2 drops every 2 hours for 2 days THEN q6hrs for 5 days OR
Gentamicin 0.3% solution 2 drops six times for 5 days

Vancomycin 15-20mg/kg IV BID + (one of the following)