Storage and Handling for Hib Vaccines

Proper vaccine storage and handling practices play an important role in protecting individuals and communities from vaccine-preventable diseases. For general recommendations and guidance, see Vaccine Storage and Handling. Provided below is guidance specific to Haemophilus influenzae type b (Hib) vaccines.

 

Temperature

• Store all Hib-containing vaccine refrigerated between 2°C and 8°C (36°F and 46°F).
• Do not freeze vaccine or diluents, or expose to freezing temperatures. If the vaccine has been exposed to inappropriate conditions/temperatures or handled improperly, store the vaccine at the appropriate temperature, isolate from other vaccines, mark “Do NOT Use,” and consult the vaccine manufacturer and/or your state or local immunization program for guidance.

 

Storage

• Store Hib vaccine in the original packaging.
  • For Hib vaccines that require reconstitution (Pentacel^®, ActHIB^®, Hiberix^®), diluent and vaccine are packaged together and should be stored together in the refrigerator.

 

Reconstitution

• For Hib vaccine that requires reconstitution (Pentacel^®, ActHIB^®, Hiberix^®), do NOT use if the reconstituted vaccine cannot be resuspended with thorough agitation.
  • The ActHIB^® in Pentacel^® should only be reconstituted with the DTaP-IPV liquid provided by the manufacturer.
  • Single-antigen ActHIB^® should only be reconstituted with the 0.4% sodium chloride provided.
  • Hiberix^® should only be reconstituted with the 0.9% sodium chloride provided.
  • Stock vials of normal saline should never be used to reconstitute these vaccines.

 

Disposal

• Discard vaccine vials and syringes using proper medical waste disposal procedures.

 

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