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FIGURE J. DISTRIBUTION OF AZITHROMYCIN MINIMUM INHIBITORY CONCENTRATIONS (MICs) AMONG GISP ISOLATES, 2011-2015

Percentage
20112012201320142015
CLINICAzithromycin
ALBUQUERQUE<=0.03 26.3 13.2 18.7 19.3 17.4
0.06 29.6 17.1 18.0 15.8 20.0
0.125 18.4 32.2 32.4 23.7 20.0
0.25 15.1 19.7 20.9 28.1 34.8
0.5 7.9 14.5 7.9 11.4 6.1
1.0 2.6 3.3 2.2 1.8 1.7
ATLANTA<=0.03 26.7 23.5 23.0 16.7 18.4
0.06 22.0 18.8 14.3 21.3 11.4
0.125 26.7 31.8 24.0 19.0 28.8
0.25 14.8 17.3 24.0 22.0 23.1
0.5 9.4 8.7 13.3 18.3 15.1
1.0 0.4 . 1.3 2.3 2.7
2.0 . . . 0.3 .
>=4.0 . . . . 0.7
BIRMINGHAM<=0.03 3.8 2.7 2.6 3.1 1.1
0.06 13.7 10.7 12.4 11.7 5.1
0.125 32.1 36.0 33.3 27.8 28.6
0.25 46.2 40.7 43.8 37.7 49.7
0.5 4.2 9.7 7.8 18.4 14.3
1.0 . . . 0.9 1.1
2.0 . . . 0.4 .
>=4.0 . 0.3 . . .
BOSTON<=0.03 . . . 3.7 2.6
0.06 . . . 3.7 7.9
0.125 . . . 14.8 18.4
0.25 . . . 14.8 36.8
0.5 . . . 48.1 23.7
1.0 . . . 11.1 5.3
2.0 . . . 3.7 5.3
BUFFALO<=0.03 . . . 14.9 15.7
0.06 . . . 11.5 21.4
0.125 . . . 23.0 31.4
0.25 . . . 19.5 20.0
0.5 . . . 20.7 8.6
1.0 . . . 8.0 2.1
2.0 . . . . 0.7
>=4.0 . . . 2.3 .
CHICAGO<=0.03 3.0 2.5 1.0 12.4 8.7
0.06 3.3 5.5 5.0 11.6 20.7
0.125 17.8 20.7 17.7 15.5 26.7
0.25 39.4 29.5 38.3 16.3 29.3
0.5 29.4 32.7 27.3 28.7 6.0
1.0 6.7 8.4 8.7 10.1 6.7
2.0 . . 2.0 1.6 1.3
>=4.0 0.4 0.7 . 3.9 0.7
CLEVELAND<=0.03 2.0 1.7 2.4 5.3 8.9
0.06 6.9 14.3 16.2 5.3 17.9
0.125 9.3 20.6 10.2 6.2 39.8
0.25 32.4 32.0 34.7 14.2 26.0
0.5 41.7 30.9 34.7 54.0 6.5
1.0 7.8 0.6 1.8 10.6 0.8
2.0 . . . 0.9 .
>=4.0 . . . 3.5 .
COLUMBUS<=0.03 . . 12.0 9.7 11.3
0.06 . 8.8 9.3 9.7 9.7
0.125 . 15.0 37.7 30.3 28.0
0.25 . 58.4 29.3 32.0 33.3
0.5 . 16.8 10.3 13.3 15.3
1.0 . 0.9 1.3 3.0 2.3
2.0 . . . 2.0 .
DALLAS<=0.03 19.5 10.6 8.0 6.0 5.7
0.06 27.7 11.0 5.2 7.7 4.2
0.125 41.2 41.3 37.3 34.0 14.1
0.25 11.2 30.7 42.9 40.7 43.8
0.5 0.4 4.6 4.2 6.7 18.0
1.0 . 1.1 1.7 1.3 2.1
2.0 . 0.4 0.7 3.3 9.9
>=4.0 . 0.4 . 0.3 2.1
GREENSBORO<=0.03 25.2 21.6 6.5 4.2 1.2
0.06 18.7 11.8 14.3 15.5 10.0
0.125 28.0 32.4 18.5 22.5 19.7
0.25 21.5 24.5 44.6 31.5 40.5
0.5 6.1 8.8 15.5 22.1 22.8
1.0 0.5 1.0 0.6 3.8 5.0
2.0 . . . 0.5 0.4
>=4.0 . . . . 0.4
HONOLULU<=0.03 6.6 6.1 5.5 4.9 4.9
0.06 13.1 13.3 26.0 10.7 8.1
0.125 31.1 14.3 34.2 24.6 17.1
0.25 41.0 32.7 28.8 51.6 46.3
0.5 8.2 27.6 4.1 7.4 17.1
1.0 . 4.1 . . 0.8
2.0 . 1.0 . 0.8 3.3
>=4.0 . 1.0 1.4 . 2.4
INDIANAPOLIS<=0.03 . . 5.0 21.7 14.4
0.06 . . 7.4 23.0 17.1
0.125 . . 36.1 26.7 33.2
0.25 . . 33.1 17.0 19.5
0.5 . . 14.4 8.3 10.7
1.0 . . 4.0 1.3 2.7
2.0 . . . 1.3 1.0
>=4.0 . . . 0.7 1.3
KANSAS CITY<=0.03 1.3 0.7 0.7 1.3 3.7
0.06 1.3 9.0 2.3 3.9 10.7
0.125 13.0 21.7 32.7 31.5 28.5
0.25 38.7 41.3 44.3 41.8 35.6
0.5 41.3 26.0 16.3 19.8 15.2
1.0 4.3 1.3 3.7 1.3 3.7
2.0 . . . . 2.2
>=4.0 . . . 0.4 0.4
LAS VEGAS<=0.03 1.7 7.1 6.0 4.0 2.0
0.06 5.2 7.5 9.3 5.3 7.3
0.125 17.9 26.5 13.0 15.7 20.3
0.25 33.3 37.5 41.0 40.0 35.0
0.5 29.2 19.0 25.0 28.3 25.0
1.0 12.4 2.0 5.3 5.7 8.3
2.0 0.3 . . 0.7 1.0
>=4.0 . 0.4 0.3 0.3 1.0
LOS ANGELES<=0.03 7.5 3.4 1.0 2.3 1.2
0.06 14.4 8.1 4.6 5.8 7.4
0.125 32.2 24.8 28.4 23.4 19.8
0.25 40.2 36.9 45.4 48.0 45.7
0.5 5.7 25.5 19.1 17.5 22.2
1.0 . 0.7 1.0 1.8 .
2.0 . 0.7 0.5 . 2.5
>=4.0 . . . 1.2 1.2
MINNEAPOLIS<=0.03 2.1 2.6 1.0 3.9 11.4
0.06 2.1 7.7 6.2 1.9 15.2
0.125 8.5 12.8 2.1 4.9 12.4
0.25 34.0 28.2 26.8 17.5 27.6
0.5 34.0 43.6 48.5 30.1 15.2
1.0 19.1 3.8 14.4 19.4 8.6
2.0 . 1.3 1.0 3.9 5.7
>=4.0 . . . 18.4 3.8
NEW ORLEANS<=0.03 21.8 17.7 11.0 2.9 1.5
0.06 29.8 12.8 19.6 5.3 5.3
0.125 21.8 41.9 30.1 9.4 26.7
0.25 14.9 21.7 21.1 32.2 29.8
0.5 9.7 4.9 16.7 35.7 25.2
1.0 2.0 1.0 1.4 9.9 9.9
2.0 . . . 4.7 0.8
>=4.0 . . . . 0.8
NEW YORK CITY<=0.03 21.8 12.0 12.1 6.1 13.5
0.06 14.4 17.5 7.1 15.9 3.5
0.125 21.8 24.6 28.4 19.7 19.9
0.25 28.7 31.1 25.5 37.9 36.9
0.5 11.6 13.1 24.8 15.2 19.1
1.0 1.4 1.1 2.1 1.5 4.3
2.0 0.5 0.5 . 1.5 .
>=4.0 . . . 2.3 2.8
ORANGE COUNTY<=0.03 0.9 3.2 1.6 0.6 3.3
0.06 9.3 14.5 4.0 4.7 6.0
0.125 12.1 16.1 17.7 25.1 21.9
0.25 26.2 33.1 36.3 36.3 36.1
0.5 48.6 29.8 37.1 28.7 28.4
1.0 2.8 3.2 2.4 4.7 4.4
>=4.0 . . 0.8 . .
PHILADELPHIA<=0.03 0.3 2.0 2.3 2.3 1.3
0.06 5.2 6.0 5.0 8.7 5.7
0.125 25.7 20.7 19.0 18.0 22.0
0.25 45.5 49.7 46.7 35.3 34.3
0.5 22.6 19.3 24.7 28.7 29.0
1.0 0.7 2.0 2.0 4.7 6.3
>=4.0 . 0.3 0.3 2.3 1.3
PHOENIX<=0.03 1.0 2.7 1.0 1.7 2.7
0.06 4.7 6.7 4.3 2.7 4.0
0.125 11.3 19.7 11.3 11.0 17.7
0.25 28.0 44.0 46.0 35.0 24.7
0.5 38.7 23.7 28.0 33.3 34.3
1.0 15.0 3.0 8.3 13.0 11.0
2.0 0.7 0.3 1.0 0.3 2.0
>=4.0 0.7 . . 3.0 3.7
PONTIAC<=0.03 . 5.2 3.7 7.4 15.2
0.06 . 5.2 4.2 8.9 12.6
0.125 . 20.1 21.6 15.6 28.8
0.25 . 53.6 38.4 20.0 26.8
0.5 . 11.9 25.8 34.8 11.6
1.0 . 3.6 4.2 9.6 4.5
2.0 . 0.5 1.6 . 0.5
>=4.0 . . 0.5 3.7 .
PORTLAND<=0.03 3.6 4.3 6.2 3.1 2.0
0.06 5.4 9.6 7.0 4.7 8.1
0.125 18.0 26.1 23.3 21.1 14.9
0.25 59.9 16.5 37.2 52.3 56.8
0.5 10.8 38.3 20.9 14.1 13.5
1.0 0.6 4.3 3.9 . 0.7
2.0 . . . 0.8 3.4
>=4.0 1.8 0.9 1.6 3.9 0.7
SAN DIEGO<=0.03 1.0 2.0 2.3 2.8 2.6
0.06 9.0 8.3 6.8 4.1 5.3
0.125 8.1 13.2 24.4 15.6 22.2
0.25 35.7 34.1 33.0 37.2 30.2
0.5 41.4 37.1 31.8 32.6 33.9
1.0 3.8 5.4 1.1 7.8 5.3
2.0 1.0 . . . 0.5
>=4.0 . . 0.6 . .
SAN FRANCISCO<=0.03 7.5 . 1.1 0.3 2.7
0.06 7.5 4.7 3.0 4.7 6.0
0.125 42.0 24.4 22.7 27.0 20.7
0.25 37.7 44.2 50.2 53.7 48.3
0.5 4.7 22.9 21.9 11.7 19.0
1.0 . 3.9 0.7 1.7 1.7
2.0 . . . 0.3 1.3
>=4.0 0.5 . 0.4 0.7 0.3
SEATTLE<=0.03 15.0 2.7 4.2 5.2 3.2
0.06 9.6 15.4 2.8 2.1 1.6
0.125 22.8 16.1 16.1 14.4 17.1
0.25 44.3 36.2 54.5 57.2 48.7
0.5 7.2 26.2 19.6 12.9 20.3
1.0 0.6 3.4 2.8 3.6 4.3
2.0 . . . 1.0 2.1
>=4.0 0.6 . . 3.6 2.7
TRIPLER<=0.03 . 14.3 . 10.0 27.3
0.06 33.3 28.6 18.2 30.0 18.2
0.125 33.3 28.6 36.4 10.0 .
0.25 33.3 21.4 45.5 10.0 36.4
0.5 . 7.1 . 30.0 18.2
2.0 . . . 10.0 .
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