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Serum folate

Table 1.1.a. Serum folate: Total population 

Geometric mean and selected percentiles of serum concentrations (in ng/mL) for the total U.S. population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

5th

50th

95th

Males and Females

Total, 3 years and older

13.5

(13.1-13.8)

5.70

(5.50-6.00)

13.6

(13.2-13.9)

30.8

(29.9-32.0)

15912

3–5 years

18.5

(17.7-19.3)

9.90

(8.80-10.8)

18.3

(17.7-18.8)

34.8

(32.0-41.0)

799

6–11 years

18.1

(17.6-18.7)

9.90

(9.40-10.6)

18.0

(17.6-18.5)

33.2

(31.6-35.0)

1908

12–19 years

12.6

(12.2-13.1)

6.00

(5.60-6.30)

12.8

(12.4-13.4)

24.7

(23.0-26.6)

4332

20–39 years

11.4

(11.0-11.9)

5.10

(4.80-5.40)

11.2

(10.8-11.8)

25.1

(23.4-26.9)

3184

40–59 years

12.8

(12.3-13.2)

5.50

(5.20-5.90)

12.9

(12.4-13.3)

28.7

(27.1-30.1)

2674

60 years and older

16.8

(16.3-17.3)

6.80

(6.40-7.20)

17.0

(16.4-17.6)

40.3

(37.4-43.0)

3015

Males

Total, 3 years and older

12.8

(12.4-13.2)

5.50

(5.20-5.90)

13.0

(12.5-13.4)

28.3

(27.4-29.4)

7747

3–5 years

18.2

(17.1-19.4)

9.40

(8.60-10.7)

17.7

(16.4-18.6)

41.0

(31.2-44.8)

417

6–11 years

17.8

(17.0-18.6)

9.70

(8.90-10.7)

17.7

(16.8-18.4)

32.3

(29.6-35.9)

973

12–19 years

12.5

(12.0-13.0)

6.00

(5.50-6.30)

12.9

(12.3-13.3)

24.6

(22.8-26.6)

2169

20–39 years

10.7

(10.3-11.2)

5.00

(4.40-5.60)

10.8

(10.2-11.3)

21.9

(19.8-23.2)

1355

40–59 years

12.3

(11.9-12.7)

5.40

(4.70-5.90)

12.4

(12.1-12.9)

26.7

(25.1-28.1)

1337

60 years and older

15.2

(14.7-15.8)

6.10

(5.70-6.70)

15.3

(14.7-16.1)

35.4

(34.1-37.6)

1496

Females

Total, 3 years and older

14.1

(13.7-14.5)

5.80

(5.60-6.20)

14.3

(13.8-14.7)

32.9

(31.2-34.5)

8165

3–5 years

18.8

(18.0-19.7)

10.3

(8.30-11.6)

18.7

(17.5-19.1)

33.5

(31.0-36.6)

382

6–11 years

18.5

(18.0-19.1)

10.0

(9.30-10.7)

18.6

(17.8-19.0)

33.4

(30.0-37.4)

935

12–19 years

12.7

(12.2-13.3)

6.20

(5.70-6.60)

12.8

(12.3-13.5)

24.8

(22.2-28.1)

2163

20–39 years

12.1

(11.6-12.6)

5.40

(5.10-5.60)

12.0

(11.4-12.8)

28.7

(26.2-30.8)

1829

40–59 years

13.2

(12.7-13.8)

5.50

(5.10-6.20)

13.4

(12.7-14.0)

30.2

(27.5-34.1)

1337

60 years and older

18.1

(17.3-18.8)

7.40

(6.80-7.80)

18.2

(17.3-18.9)

43.0

(39.8-45.6)

1519

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Table 1.1.b. Serum folate: Mexican Americans 

Geometric mean and selected percentiles of serum concentrations (in ng/mL) for Mexican Americans in the U.S. population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

5th

50th

95th

Males and Females

Total, 3 years and older

12.4

(11.9-12.9)

5.70

(5.30-6.20)

12.5

(12.0-12.9)

26.3

(24.8-28.1)

4695

3–5 years

18.1

(17.1-19.2)

10.9

(9.90-11.5)

17.7

(16.7-18.7)

33.6

(28.6-36.8)

266

6–11 years

17.7

(17.1-18.4)

10.4

(9.60-11.0)

17.3

(16.7-17.9)

31.0

(28.8-34.8)

652

12–19 years

12.4

(12.0-12.8)

6.60

(6.10-6.90)

12.6

(12.0-13.2)

22.4

(21.7-24.0)

1637

20–39 years

10.5

(9.96-11.0)

5.00

(4.20-5.60)

10.3

(9.80-11.0)

20.1

(19.4-21.9)

866

40–59 years

11.8

(11.1-12.5)

5.90

(5.10-6.50)

11.9

(11.2-12.4)

23.8

(20.6-28.0)

634

60 years and older

14.4

(13.6-15.2)

6.00

(5.00-6.90)

14.8

(13.5-15.8)

34.1

(30.2-38.7)

640

Males

Total, 3 years and older

12.0

(11.4-12.5)

5.50

(4.80-6.20)

12.1

(11.4-12.6)

25.3

(23.5-27.4)

2293

3–5 years

17.7

(16.6-18.9)

10.5†

(9.70-11.6)

17.4

(16.1-18.5)

34.0†

(27.1-44.8)

139

6–11 years

17.6

(16.7-18.5)

10.1

(9.00-11.0)

17.5

(16.4-18.4)

32.1

(26.2-42.0)

338

12–19 years

12.5

(12.0-13.1)

6.40

(5.80-7.00)

12.6

(12.0-13.3)

24.1

(22.1-26.3)

811

20–39 years

9.85

(9.24-10.5)

4.50

(3.80-5.60)

9.80

(9.20-10.6)

19.3

(17.2-20.0)

383

40–59 years

11.6

(10.8-12.5)

5.80

(5.10-6.60)

11.7

(10.7-12.6)

22.0

(18.4-28.7)

301

60 years and older

13.5

(12.5-14.5)

6.20

(5.00-7.10)

13.2

(12.2-14.8)

29.8

(24.0-48.3)

321

Females

Total, 3 years and older

12.9

(12.4-13.4)

5.90

(5.70-6.40)

13.0

(12.6-13.7)

27.2

(25.6-28.8)

2402

3–5 years

18.5

(17.1-20.0)

11.0†

(9.60-12.0)

18.3

(16.9-19.0)

31.6†

(27.4-36.6)

127

6–11 years

17.9

(17.2-18.6)

10.5

(9.60-11.7)

17.3

(16.6-18.2)

30.8

(28.8-32.1)

314

12–19 years

12.2

(11.8-12.7)

6.60

(6.10-7.00)

12.5

(11.8-13.3)

21.6

(19.8-22.4)

826

20–39 years

11.2

(10.7-11.8)

5.20

(4.90-5.90)

11.0

(10.3-11.7)

22.3

(20.0-27.6)

483

40–59 years

11.9

(11.1-12.8)

5.90

(4.60-6.50)

12.0

(11.1-12.5)

25.4

(21.4-26.6)

333

60 years and older

15.2

(14.3-16.2)

6.10

(5.00-7.20)

15.8

(14.4-16.7)

36.0

(31.5-39.6)

319

† Estimate is subject to greater uncertainty due to small cell size.

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Table 1.1.c. Serum folate: Non-Hispanic blacks 

Geometric mean and selected percentiles of serum concentrations (in ng/mL) for non-Hispanic blacks in the U.S. population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

5th

50th

95th

Males and Females

Total, 3 years and older

11.3

(10.9-11.8)

5.10

(4.60-5.30)

11.1

(10.6-11.6)

25.5

(23.9-27.1)

3716

3–5 years

16.9

(16.0-17.8)

9.80

(8.70-10.5)

16.2

(15.1-17.8)

34.8

(28.2-39.3)

235

6–11 years

16.9

(16.2-17.6)

9.60

(8.80-10.6)

16.4

(15.8-17.4)

31.8

(28.0-39.5)

604

12–19 years

10.9

(10.5-11.4)

5.30

(5.00-5.70)

11.0

(10.5-11.4)

19.8

(19.0-21.0)

1256

20–39 years

9.73

(9.18-10.3)

5.10

(4.50-5.40)

9.60

(9.10-10.4)

19.8

(18.7-21.4)

593

40–59 years

10.3

(9.86-10.8)

4.40

(4.10-5.10)

10.1

(9.60-10.8)

22.7

(19.4-26.0)

541

60 years and older

12.7

(11.6-13.8)

4.80

(4.20-5.40)

12.2

(11.0-14.0)

38.1

(31.1-43.3)

487

Males

Total, 3 years and older

10.9

(10.5-11.3)

4.80

(4.40-5.10)

10.8

(10.5-11.3)

22.7

(21.2-25.0)

1822

3–5 years

16.6

(15.3-17.9)

9.00†

(7.50-10.6)

15.6

(14.4-17.2)

36.5†

(26.1-55.9)

122

6–11 years

17.0

(16.3-17.8)

9.60

(8.80-10.8)

16.6

(15.9-17.6)

31.6

(26.8-39.5)

305

12–19 years

11.0

(10.5-11.5)

5.10

(4.60-5.80)

11.2

(10.5-11.7)

20.1

(19.2-22.2)

640

20–39 years

9.17

(8.63-9.74)

4.50

(3.50-5.10)

9.50

(8.40-10.2)

17.4

(16.3-19.5)

249

40–59 years

9.69

(9.20-10.2)

4.20

(3.00-4.70)

9.80

(9.20-10.2)

19.2

(17.8-20.6)

274

60 years and older

11.3

(10.3-12.4)

4.60

(3.90-5.20)

11.3

(9.90-12.6)

33.8

(20.0-40.4)

232

Females

Total, 3 years and older

11.7

(11.1-12.3)

5.40

(4.80-5.70)

11.2

(10.7-11.9)

27.4

(25.1-30.4)

1894

3–5 years

17.2

(15.8-18.8)

10.2†

(7.80-10.9)

17.2

(15.2-18.8)

30.9†

(27.1-36.3)

113

6–11 years

16.7

(16.0-17.5)

9.60

(7.90-10.5)

16.3

(15.5-17.3)

32.5

(27.1-38.4)

299

12–19 years

10.8

(10.3-11.4)

5.40

(5.00-5.80)

10.8

(10.3-11.3)

19.4

(18.3-21.0)

616

20–39 years

10.2

(9.49-10.9)

5.40

(4.50-5.70)

9.70

(9.20-10.7)

21.4

(19.2-24.0)

344

40–59 years

10.9

(10.2-11.7)

4.70

(3.50-5.90)

10.6

(9.50-12.1)

24.8

(19.6-29.2)

267

60 years and older

13.6

(12.2-15.2)

5.10

(3.80-6.60)

12.7

(11.6-14.9)

39.5

(30.5-48.0)

255

† Estimate is subject to greater uncertainty due to small cell size.

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Table 1.1.d. Serum folate: Non-Hispanic whites 

Geometric mean and selected percentiles of serum concentrations (in ng/mL) for non-Hispanic whites in the U.S. population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

5th

50th

95th

Males and Females

Total, 3 years and older

14.1

(13.6-14.6)

6.00

(5.70-6.30)

14.2

(13.7-14.8)

32.0

(30.9-33.3)

6147

3–5 years

19.6

(18.3-21.1)

10.1†

(8.30-12.3)

18.9

(17.8-20.2)

38.0†

(31.5-48.9)

219

6–11 years

18.7

(17.9-19.5)

9.70

(8.90-10.8)

18.8

(17.9-19.5)

34.2

(31.6-37.8)

494

12–19 years

13.3

(12.8-13.9)

6.20

(5.70-6.70)

13.6

(13.1-14.3)

26.5

(24.0-27.6)

1073

20–39 years

11.9

(11.4-12.6)

5.50

(4.80-5.90)

12.2

(11.2-12.9)

26.3

(24.0-29.1)

1381

40–59 years

13.3

(12.7-13.8)

5.60

(5.20-6.10)

13.3

(12.9-14.0)

29.8

(27.4-31.0)

1276

60 years and older

17.4

(16.8-18.0)

7.20

(6.60-7.60)

17.8

(16.9-18.4)

41.0

(37.4-43.5)

1704

Males

Total, 3 years and older

13.3

(12.9-13.9)

6.00

(5.60-6.30)

13.6

(13.0-14.1)

29.4

(28.1-30.6)

3013

3–5 years

19.2

(17.2-21.4)

9.00†

(7.80-11.1)

18.7

(16.3-19.9)

42.0†

(29.9-57.6)

116

6–11 years

18.2

(17.0-19.5)

8.90

(7.60-11.0)

18.0

(16.8-19.2)

34.7

(29.7-38.0)

260

12–19 years

13.0

(12.4-13.7)

6.20

(5.60-6.80)

13.4

(12.8-13.9)

26.0

(22.8-27.3)

536

20–39 years

11.3

(10.6-12.0)

5.40

(4.40-6.10)

11.3

(10.4-12.4)

23.0

(20.2-24.5)

577

40–59 years

12.7

(12.2-13.3)

5.70

(5.20-6.40)

13.0

(12.3-13.5)

27.3

(25.4-28.8)

666

60 years and older

15.8

(15.1-16.5)

6.30

(6.10-7.30)

16.0

(15.2-17.0)

35.9

(33.6-37.6)

858

Females

Total, 3 years and older

14.9

(14.3-15.4)

6.10

(5.80-6.50)

15.1

(14.5-15.7)

34.2

(32.4-35.8)

3134

3–5 years

20.1

(18.8-21.5)

11.6†

(8.30-14.1)

19.1

(18.4-21.6)

33.5†

(28.9-39.0)

103

6–11 years

19.2

(18.3-20.1)

10.2

(8.90-11.1)

19.4

(18.8-20.2)

33.6

(29.4-40.3)

234

12–19 years

13.7

(12.9-14.5)

6.40

(5.20-7.10)

13.9

(13.2-14.7)

26.6

(23.0-31.6)

537

20–39 years

12.6

(12.0-13.4)

5.60

(5.10-5.90)

13.0

(11.8-13.7)

30.4

(26.3-32.4)

804

40–59 years

13.8

(13.1-14.6)

5.70

(5.10-6.30)

13.9

(12.9-15.1)

31.0

(28.7-35.0)

610

60 years and older

18.8

(18.0-19.7)

7.70

(7.20-8.60)

18.9

(18.0-19.8)

43.6

(40.0-46.1)

846

† Estimate is subject to greater uncertainty due to small cell size.

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  • Page last reviewed: January 30, 2012
  • Page last updated: June 20, 2012
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