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Registry of Toxic Effects of Chemical Substances (RTECS)

Cadmium sulfide

RTECS #

EV3150000

CAS #

1306-23-6; 106496-20-2

Updated

September 201

Molecular Weight

144.46

Molecular Formula

CdS

Synonyms

C.P. Golden Yellow 55
Cadmium golden 366
Cadmium lemon Yellow 527
Cadmium monosulfide
Cadmium Orange
Cadmium primrose 819
Cadmium sulphide
Cadmium Yellow
Cadmium Yellow 000
Cadmium Yellow 10G Conc
Cadmium Yellow 892
Cadmium Yellow Conc. Deep
Cadmium Yellow Conc. Golden
Cadmium Yellow Conc. Lemon
Cadmium Yellow Conc. Primrose
Cadmium Yellow OZ Dark
Cadmium Yellow Primrose 47-4100
Cadmopur Golden Yellow N
Cadmopur Yellow
Capsebon
Ferro Lemon Yellow
Ferro Orange Yellow
Ferro Yellow
Greenockite
GSK
NCI-C02711
PC 108
Primrose 1466

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysisleukocyte/human62 µg/LPJACAW 48,133,1972
DNA Damageovary/hamster10 mg/LCRNGDP 3,657,1982
morphological transformembryo/hamster1 mg/LCNREA8 42,2757,1982

Tumorigenic Data and References

Route/OrganismDoseEffectReference
intramuscular/rat lowest published toxic dose: 120 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application		BJCAAI 20,190,1966
subcutaneous/rat toxic dose: 135 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application		PBPHAW 14,47,1978
subcutaneous/rat toxic dose: 250 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Blood: Lymphoma including Hodgkin's disease

Tumorigenic: Tumors at site of application		NATUAS 198,1213,1963
subcutaneous/rat lowest published toxic dose: 90 mg/kgTumorigenic: Carcinogenic by RTECS criteria

Tumorigenic: Tumors at site of application		BJCAAI 20,190,1966

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat Lethal concentration: >140 mg/m3/2HNTIS** OTS0539392
oral/mouse lethal dose (50 percent kill): 1166 mg/kg41HTAH -,14,1978
oral/rat lethal dose (50 percent kill): 7080 mg/kg41HTAH -,14,1978

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.002 mg(Cd)/m3 (resp)DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Suspected human carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 2,74,1973
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 11,39,1976
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 58,119,1993
International Agency for Research on Cancer (IARC)Cancer Review:Human Sufficient EvidenceIMEMDT 58,119,1993
International Agency for Research on Cancer (IARC)Cancer Review:Group 1IMEMDT 58,119,1993
TOXICOLOGY REVIEWFCTXAV 9,105,1971
TOXICOLOGY REVIEWENTOX* -,375,2005
TOXICOLOGY REVIEWHBTME* ,445,2007
TOXICOLOGY REVIEWHUTOX* -,515,1996
TOXICOLOGY REVIEWFCTOD7 49,2921,2011

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.2 mg(Cd)/m3DTLVS* 3,34,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-ARAB Republic of Egypttime-weighted average 0.05 mg(Cd)/m3, JAN1993
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.01 mg(Cd)/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.002 mg(Cd)/m3 (resp. dust), Carcinogen, MAR2002
Occupational Exposure Limit-BELGIUMtime-weighted average 0.01 mg(Cd)/m3 (inhal. dust), Carcinogen, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.005 mg(Cd)/m3 (fume, dust), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 0.02 mg(Cd)/m3, skin, NOV2011
Occupational Exposure Limit-FRANCEVME 0.05 mg(Cd)/m3, FEB2006
Occupational Exposure Limit-HUNGARYtime-weighted average 0.015 mg(Cd)/m3, short term exposure limit 0.06 mg(Cd)/m3, SEP2000
Occupational Exposure Limit-JAPANOccupational Exposure Limit 0.05 mg(Cd)/m3, 1 carc, MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 0.05 mg(Cd)/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.002 mg(Cd)/m3 (inhalable), 2004
Occupational Exposure Limit-MEXICOtime-weighted average 0.01 mg(Cd)/m3 (total dust), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.01 mg(Cd)/m3 (inspirable dust), JAN2002
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.002 mg(Cd)/m3 (respirable dust), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.05 mg(Cd)/m3, JAN1999
Occupational Exposure Limit-POLANDMAC(time-weighted average) dust 0.04 mg(Cd)/m3, MAC(short term exposure limit) dust 0.2 mg(Cd)/m3, JAN1999
Occupational Exposure Limit-POLANDMAC(time-weighted average) fume 0.02 mg(Cd)/m3, MAC(short term exposure limit) fume 0.05 mg(Cd)/m3, JAN1999
Occupational Exposure Limit-RUSSIAtime-weighted average 0.01 mg(Cd)/m3, short term exposure limit 0.05 mg(Cd)/m3, Carcinogen, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 0.02 mg(Cd)/m3 (total dust), Carcinogen, JUN2005
Occupational Exposure Limit-SWEDENtime-weighted average 0.005 mg(Cd)/m3 (resp. dust), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.015 mg(Cd)/m3, carc 2, inhal, skin, JAN2011
Occupational Exposure Limit-THAILANDtime-weighted average 0.2 mg(Cd)/m3, short term exposure limit 0.5 mg(Cd)/m3, JAN1993
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.005 mg(Cd)/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.2 mg(Cd)/m3, JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 0.2 mg(Cd)/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.03 mg(Cd)/m3, carc, OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CADMIUM, dust and fume-airCarcinogen lowest feasible conc.NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 83628; Number of Industries 32; Total Number of Facilities 1625; Number of Occupations 38; Total Number of Employees Exposed 42562; Total Number of Female Employees Exposed 16685
National Occupational Hazard Survey 1974Hazard Code 83628; Number of Industries 29; Total Number of Facilities 1041; Number of Occupations 41; Total Number of Employees Exposed 19293

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat
EPA GENETOX PROGRAM 1988, Positive: In vitro cytogenetics-human lymphocyte
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NTP 11th Report on Carcinogens,2004:Known to be human carcinogen

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