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Registry of Toxic Effects of Chemical Substances (RTECS)

Vanadium pentoxide (fume)

RTECS #

YW2460000

CAS #

1314-62-1

Updated

April 2012

Molecular Weight

181.88

Molecular Formula

O5V2

Synonyms

RCRA waste number P120
Vanadium (OSHA)
Vanadium pentoxide, fume (ACGIH)
Vanadium pentoxide, nonfused form, fume (ACGIH)

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 27 µg/m3/24H/70D- continuousKidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase		GISAAA 31(7),8,1966
inhalation/rat lowest published toxic concentration: 100 µg/m3/24H/17W- continuousKidney, Ureter, and Bladder: Changes in bladder weight

Blood: Changes in erythrocyte (RBC) count

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Monoamine oxidase		GISAAA 46(2),17,1981

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEW85DHAX V,46,1974

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.05 mg/m3 (fume)DTLVS* 3,275,1971
Occupational Exposure Limit-DENMARKtime-weighted average 0.03 mg(V)/m3, MAY2011
Occupational Exposure Limit-ICELANDtime-weighted average 0.2 mg(V)/m3, NOV2011
Occupational Exposure Limit-POLANDMAC(time-weighted average) 0.05 mg/m3, MAC(short term exposure limit) 0.1 mg/m3, JAN1999
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)ceiling concentration 0.1 mg(V2O5)/m3, fumeCFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)ceiling concentration 0.1 mg(V2O5)/m3, fumeCFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)ceiling concentration 0.5 mg(V2O5)/m3, dustCFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)ceiling concentration 0.1 mg(V2O5)/m3, fumeCFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)ceiling concentration 0.1 mg(V2O5)/m3, fumeCFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO VANADIUM (as V2O5), resp dust/fume-airceiling concentration 0.05 mg/m3/15MNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 76210; Number of Industries 6; Total Number of Facilities 67; Number of Occupations 17; Total Number of Employees Exposed 4468; Total Number of Female Employees Exposed 541
National Occupational Hazard Survey 1974Hazard Code 76210; Number of Industries 7; Total Number of Facilities 333; Number of Occupations 12; Total Number of Employees Exposed 2562

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Vanadium oxides, 7504
NIOSH Analytical Method, 1996: Elements by ICP, 7300
NTP Carcinogenesis studies; on test (two year studies), October 2000
On EPA IRIS database
OSHA ANALYTICAL METHOD #ID-185

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