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Registry of Toxic Effects of Chemical Substances (RTECS)

o-Toluamide, 3,5-dinitro-

RTECS #

XS4200000

CAS #

148-01-6

Updated

September 201

Molecular Weight

225.18

Molecular Formula

C8H7N3O5

Synonyms

2-Methyl-3,5-dinitrobenzamide
Benzamide, 2-methyl-3,5-dinitro-
Coccidine A
Coccidot
D.O.T.
Dinitolmid
Dinitolmide
Dinitolmide (ACGIH)
Zoalene
Zoamix

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
DNA repair/Bacillus subtilis1 mg/discMUREAV 77,21,1980
mutation in microorganisms/Salmonella typhimurium500 µg/plate (+/-enzymatic activation step)MUREAV 77,21,1980

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intravenous/Dog lethal dose (50 percent kill): 75 mg/kgPCOC** -,1252,1966
oral/rat lethal dose (50 percent kill): 600 mg/kg29ZVAB -,537,1969

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 1 mg/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 5 mg/m3, JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 5 mg/m3;KZW 10 mg/m3, inhal, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 5 mg/m3, MAR2002
Occupational Exposure Limit-FRANCEVME 5 mg/m3, FEB2006
Occupational Exposure Limit-KOREAtime-weighted average 5 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 5 mg/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 5 mg/m3, JAN2002
Occupational Exposure Limit-PERUtime-weighted average 5 mg/m3, JUL2005
Occupational Exposure Limit-SWITZERLANDMAK-week 5 mg/m3, inhal, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 5 mg/m3, 2003

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO DINITROLMIDE-air10H time-weighted average 5 mg/m3NIOSH* DHHS #95-121,1995
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