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Registry of Toxic Effects of Chemical Substances (RTECS)

Sulfur dioxide

RTECS #

WS4550000

CAS #

7446-09-5; 8014-94-6; 12396-99-5; 83008-56-4; 89125-89-3

Updated

September 201

Molecular Weight

64.06

Molecular Formula

O2S

Synonyms

Fermenicide liquid
Fermenicide powder
Schwefeldioxyd (German)
Siarki dwutlenek (Polish)
Sulfur dioxide (ACGIH:OSHA)
Sulfur oxide
Sulfur superoxide
Sulfurous acid anhydride
Sulfurous anhydride
Sulfurous oxide
Sulphur dioxide

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 6 ppm/32D mildJPCAAC 10,17,1960

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysismultiple/human42 mg/m3MUREAV 359,25,1996
Cytogenetic Analysisother cell types/domestic animal5 mmol/LMUREAV 39,149,1977
Cytogenetic Analysisother cell types/cattle2500 µmol/LMUREAV 39,149,1977
Cytogenetic Analysisinhalation/mouse14 µg/L/4H/7DMUTAEX 17,215,2002
DNA adductinhalation/rat72 mg/kg/300D- intermittentCALEDQ 139,189,1999
DNA Damageinhalation/mouse7 µg/LTXAPA9 197,239,2004
DNA Damageinhalation/mouse14 µg/L/7D- intermittentEMMUEG 46,150,2005
DNA Damagelymphocyte/human5700 ppbMUREAV 39,149,1977
DNA inhibitionlymphocyte/human5700 ppbMUREAV 39,149,1977
micronucleus testinhalation/mouse28 µg/L/5D- intermittentINHTE5 15,1053,2003
mutation in microorganisms/Other microorganisms10 mmol/L (-enzymatic activation step)MUREAV 39,149,1977
mutation in microorganisms/Saccharomyes cerevisiae5 µmol/L (-enzymatic activation step)MUREAV 39,149,1977
other mutation test systems/Escherichia coli2 mmol/LCBINA8 43,289,1983
other mutation test systemslymphocyte/human5700 ppbMUREAV 39,149,1977
other mutation test systemsother cell types/cattle2500 µmol/LMUREAV 39,149,1977
sex chromosome loss and nondisjunctionoral/Drosophila melanogaster200 µmol/LMUREAV 39,149,1977
sister chromatid exchangemultiple/human42 mg/m3MUREAV 359,25,1996

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
inhalation/rat 4 mg/m3/24H (72D prior to copulation)Reproductive: Maternal effects: Menstrual cycle changes or disorders

Reproductive: Maternal effects: Parturition

Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated)
HYSAAV 35(4-6),277,1970
inhalation/rat 4 mg/m3/24H (72D prior to copulation)Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)

Reproductive: Effects on newborn: Delayed effects
HYSAAV 35(4-6),277,1970
inhalation/rat 4970 µg/m3/12H (12W prior to copulation)Reproductive: Maternal effects: Menstrual cycle changes or disorders

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
HYSAAV 36(7-9),178,1971
inhalation/rat 30 ppm/6H (21W male)Reproductive: Paternal effects: Testes, epididymis, sperm ductJTEHD6 21,141,1987
inhalation/mouse 25 ppm/7H (6-15D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)FCTXAV 18,743,1980
inhalation/mouse 25 ppm/7H (6-15D pregnant)Reproductive: Specific developmental abnormalities: Musculoskeletal systemNTIS** CONF-771017
inhalation/mouse 32 ppm/24H (7-18D pregnant)Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)

Reproductive: Effects on newborn: Behavioral
TJADAB 31,9B,1985
inhalation/mouse 5 ppm (9D prior to copulation/1-14D pregnant)Reproductive: Effects on newborn: BehavioralNETEEC 20,543,1998
inhalation/rabbit 70 ppm/7H (6-18D pregnant)Reproductive: Specific developmental abnormalities: Musculoskeletal systemNTIS** CONF-771017

Tumorigenic Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lowest published toxic concentration: 500 ppm/5M/30W- intermittentTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors
BJCAAI 21,606,1967
inhalation/rat lowest published toxic concentration: 72 mg/kg/300D- intermittentTumorigenic: Carcinogenic by RTECS criteria

Tumorigenic: Facilitates action of known carcinogens

Lung, Thorax, or Respiration: Tumors
CALEDQ 139,189,1999

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/frog Lowest published lethal concentration: 1 pph/15MHBAMAK 4,1396,1935
inhalation/guinea pig lowest published toxic concentration: 100 ppm/30MCardiac: Pulse rate decreased with fall in BPTOXID9 66,193,2002
inhalation/guinea pig lowest published toxic concentration: 100 ppm/1HTOXID9 60,425,2001
inhalation/guinea pig lowest published toxic concentration: 50 ppm/1HOlfaction: Other olfaction effects

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Other changes
TOXID9 60,425,2001
inhalation/guinea pig Lowest published lethal concentration: 1039 ppm/24HCBTIAE 10,281,1939
inhalation/human lowest published toxic concentration: 2.2 mg/m3/30MLung, Thorax, or Respiration: Other changesVCVN5* -,226,1993
inhalation/human lowest published toxic concentration: 2.9 mg/m3/60MOlfaction: Other olfaction effectsVCVN5* -,226,1993
inhalation/human lowest published toxic concentration: 2.9 mg/m3/10MCardiac: Pulse rate increased without fall in BP

Lung, Thorax, or Respiration: Dyspnea
VCVN5* -,226,1993
inhalation/human Lowest published lethal concentration: 1000 ppm/10MLung, Thorax, or Respiration: Respiratory depressionCTOXAO 5,198,1972
inhalation/human lowest published toxic concentration: 3 ppm/5DLung, Thorax, or Respiration: Other changesTXAPA9 22,319,1972
inhalation/human lowest published toxic concentration: 12 ppm/1HLung, Thorax, or Respiration: Other changesSAIGBL 14,449,1972
inhalation/human Lowest published lethal concentration: 3000 ppm/5MTABIA2 3,231,1933
inhalation/mammal (species unspecified) lowest published toxic concentration: 19.6 mg/m3Brain and Coverings: Other degenerative changes

Lung, Thorax, or Respiration: Other changes

Endocrine: Other changes
VCVN5* -,224,1993
inhalation/mammal (species unspecified) lowest published toxic concentration: 80 mg/m3Olfaction: Change in sensation of smell

Lung, Thorax, or Respiration: Dyspnea
VCVN5* -,224,1993
inhalation/mammal (species unspecified) lowest published toxic concentration: 740 mg/m3Olfaction: Other olfaction effects

Gastrointestinal: Decreased motility or constipation
VCVN5* -,224,1993
inhalation/mammal (species unspecified) Lowest published lethal concentration: 3000 ppm/5MAEPPAE 138,65,1928
inhalation/mouse lethal concentration (50 percent kill): 3000 ppm/30MBehavioral: Convulsions or effect on seizure threshold

Behavioral: Change in motor activity (specific assay)
JCTODH 4,236,1977
inhalation/mouse lethal concentration (50 percent kill): 3000 ppm/30MENTOX* ,115,2005
inhalation/rat lowest published toxic concentration: 20 mg/m3/5HBehavioral: Change in motor activity (specific assay)

Behavioral: Aggression
VCVN5* -,225,1993
inhalation/rat lowest published toxic concentration: 30 mg/m3Peripheral Nerve and Sensation: Recording from peripheral motor nerve

Blood: Normocytic anemia

Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)
VCVN5* -,225,1993
inhalation/rat lethal concentration (50 percent kill): 2168 mg/m3Behavioral: Change in motor activity (specific assay)

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVN5* -,224,1993
inhalation/rat lowest published toxic dose: 57.3 mg/m3/6HVascular: BP lowering not characterized in autonomic sectionINHTE5 15,951,2003
inhalation/rat lowest published toxic concentration: 80 mg/m3/4HLung, Thorax, or Respiration: Other changesTPKVAL 14,73,1975
inhalation/rat lowest published toxic concentration: 57.3 mg/m3/6HVascular: BP lowering not characterized in autonomic sectionINHTE5 15,951,2003
inhalation/rat lethal concentration (50 percent kill): 2520 ppm/1HENTOX* ,115,2005

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/cattle lowest published toxic concentration: 1 ppm/10D- intermittentLung, Thorax, or Respiration: Other changes

Blood: Other changes

Immunological Including Allergic: Decrease in cellular immune response
TOXID9 72,230,2003
inhalation/cattle lowest published toxic concentration: 5 ppm/7D- intermittentLung, Thorax, or Respiration: Other changes

Blood: Other changes

Immunological Including Allergic: Decrease in cellular immune response
TOXID9 72,230,2003
inhalation/Dog lowest published toxic concentration: 1 ppm/90M/1Y- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchiAEHLAU 30,249,1975
inhalation/Dog lowest published toxic concentration: 500 ppm/2H/21W- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Respiratory depression
JTEHD6 13,945,1984
inhalation/guinea pig lowest published toxic concentration: 10 ppm/1H/30D- intermittentLiver: Other changes

Kidney, Ureter, and Bladder: Other changes

Biochemical: Metabolism (intermediary): Lipids including transport
INHEAO 23,81,1985
inhalation/human lowest published toxic concentration: 4.5 mg/m3/24H/5D- continuousRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldVCVN5* -,227,1989
inhalation/mouse lowest published toxic concentration: 22 mg/m3/6H/7D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductasesETOPFR 13,1,2003
inhalation/mouse lowest published toxic concentration: 56 mg/m3/6H/7D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: CatalasesETOPFR 13,1,2003
inhalation/mouse lowest published toxic concentration: 14 mg/m3/7D- intermittentLung, Thorax, or Respiration: Other changes

Immunological Including Allergic: Increase in cellular immune response
INHTE5 17,303,2005
inhalation/mouse lowest published toxic concentration: 28 mg/m3/5D- intermittentLung, Thorax, or Respiration: Changes in lung weight

Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in kidney weight
INHTE5 15,1053,2003
inhalation/mouse lowest published toxic concentration: 64 mg/m3/7D- intermittentBrain and Coverings: Other degenerative changes

Lung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
AECTCV 45,423,2003
inhalation/mouse lowest published toxic concentration: 22 mg/m3/7D- intermittentGastrointestinal: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes
INHTE5 15,397,2003
inhalation/mouse lowest published toxic concentration: 56 mg/m3/7D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Catalases

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases
INHTE5 15,397,2003
inhalation/mouse lowest published toxic concentration: 56 mg/m3/7D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductasesINHTE5 15,397,2003
inhalation/mouse lowest published toxic concentration: 112 mg/m3/7D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: CatalasesINHTE5 15,397,2003
inhalation/mouse lowest published toxic concentration: 10 ppm/7W- intermittentBehavioral: Food intake (animal)

Behavioral: Alteration of operant conditioning

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
NETEEC 29,211,2007
inhalation/mouse lowest published toxic dose: 10 ppm/7D- intermittentBlood: Other changesMUREAV 697,38,2010
inhalation/rabbit lowest published toxic concentration: 200 mg/m3/3H/13W- intermittentCardiac: Other changes

Liver: Other changes

Blood: Hemorrhage
GISAAA 24(6),22,1959
inhalation/rat lowest published toxic concentration: 28.6 mg/m3/3D- intermittentVascular: BP lowering not characterized in autonomic sectionINHTE5 15,951,2003
inhalation/rat lowest published toxic concentration: 28 mg/m3/7D- intermittentLiver: Other changes

Biochemical: Metabolism (intermediary): Other proteins
TXCYAC 216,253,2005
inhalation/rat lowest published toxic concentration: 28 mg/m3/7D- intermittentLung, Thorax, or Respiration: Other changes

Liver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
TOLED5 160,34,2005
inhalation/rat lowest published toxic concentration: 28 mg/m3/7D- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)
TOLED5 160,34,2005
inhalation/rat lowest published toxic concentration: 300 ppm/4H/44D- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other hydrolases

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other transferases
EJPHAZ 487,7,2004
inhalation/rat lowest published toxic concentration: 300 ppm/2H/10D- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Respiratory depression
TXAPA9 197,175,2004
inhalation/rat lowest published toxic concentration: 10 ppm/1H/6W- intermittentBrain and Coverings: Other degenerative changes

Eye: Other eye effects

Behavioral: Food intake (animal)
NETEEC 25,587,2003
inhalation/rat lowest published toxic concentration: 10 ppm/1H/6W- intermittentBehavioral: Fluid intake

Biochemical: Metabolism (intermediary): Lipids including transport
NETEEC 25,587,2003
inhalation/rat lowest published toxic concentration: 8.5 mg/m3/24H/65D- continuousPeripheral Nerve and Sensation: Recording from peripheral motor nerve

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Emphysema
VCVN5* -,228,1989
inhalation/rat lowest published toxic concentration: 143 mg/m3/6H/17W- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Liver: Hepatitis (hepatocellular necrosis), diffuse

Endocrine: Hyperglycemia
VCVN5* -,229,1989
inhalation/rat lowest published toxic concentration: 51.2 mg/m3/6H/17W- intermittentOlfaction: Other olfaction effects

Gastrointestinal: Other changes

Liver: Liver function tests impaired
VCVN5* -,229,1989
inhalation/rat lowest published toxic concentration: 100 ppm/5H/28D- intermittentLung, Thorax, or Respiration: Other changes

Liver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes
CBPCEE 114,89,1996
inhalation/rat lowest published toxic concentration: 4910 µg/m3/6H/17W- intermittentBlood: Pigmented or nucleated red blood cells

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases
GISAAA 41(5),6,1976
inhalation/rat lowest published toxic concentration: 500 µg/m3/96D- intermittentBrain and Coverings: Changes in surface EEG

Behavioral: Change in motor activity (specific assay)

Biochemical: Metabolism (intermediary): Xanthine, purine or nucleotides including urate
GISAAA 34(2),3,1969
inhalation/rat lowest published toxic concentration: 400 ppm/3H/6W- intermittentLung, Thorax, or Respiration: Structural or functional change in trachea or bronchiATSUDG 9,431,1986
inhalation/rat lowest published toxic concentration: 10 ppm/24H/14D- intermittentBehavioral: Food intake (animal)

Liver: Other changes

Biochemical: Metabolism (intermediary): Lipids including transport
ARTODN 70,164,1996
parenteral/rat lowest published toxic dose: 250 ppm/4D- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Other
TOXID9 44,190,2005

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-short term exposure limit 0.25 ppmDTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal Limited EvidenceIMEMDT 54,131,1992
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 54,131,1992
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMEMDT 54,131,1992
TOXICOLOGY REVIEWMUREAV 558,7,2004
TOXICOLOGY REVIEWNTIS** PB228-002
TOXICOLOGY REVIEWEVHPAZ 10,35,1975
TOXICOLOGY REVIEWGEIGAI 20,299,1973
TOXICOLOGY REVIEWAEHLAU 16,903,1968
TOXICOLOGY REVIEWENVRAL 16,139,1978
TOXICOLOGY REVIEWNTIS** CONF-691001
TOXICOLOGY REVIEWAMIHBC 10,455,1954
TOXICOLOGY REVIEWTPHSDY 23,311,2002
TOXICOLOGY REVIEWTOLED5 140-141,195,2003
TOXICOLOGY REVIEWTOLED5 140-141,213,2003
TOXICOLOGY REVIEWTPHSDY 24,609,2003
TOXICOLOGY REVIEWNETOX* 26,555,2005
TOXICOLOGY REVIEWDIMON* 46,551,2000
TOXICOLOGY REVIEWENTOX* -,115,2005
TOXICOLOGY REVIEWMUREAV 658,124,2008
TOXICOLOGY REVIEWHUTOX* -,259,1996
TOXICOLOGY REVIEWHUTOX* -,661,1996
TOXICOLOGY REVIEWMUREAV 674,45,2009
TOXICOLOGY REVIEWMUREAV 674,62,2009
TOXICOLOGY REVIEWMUREAV 674,73,2009
TOXICOLOGY REVIEWMUREAV 636,144,2007
TOXICOLOGY REVIEWMUREAV 636,36,2007
TOXICOLOGY REVIEWPRESR* 7,123,2006
TOXICOLOGY REVIEWMUREAV 717,38,2011
TOXICOLOGY REVIEWMUREAV 717,46,2011

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESSupportedRBREV* -,320,1998
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 5 ppm (13 mg/m3)DTLVS* 3,238,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-ARAB Republic of Egypttime-weighted average 5 ppm (13 mg/m3), JAN1993
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2 ppm (5.2 mg/m3), short term exposure limit 5 ppm (13 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 2 ppm (5 mg/m3);KZW 4 ppm (10 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 2 ppm (5.3 mg/m3), short term exposure limit 5 ppm (13 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 ppm (1.3 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 1 ppm (2.7 mg/m3), short term exposure limit 4 ppm (11 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 2 ppm (5 mg/m3), VLE 5 ppm (10 mg/m3), FEB2006
Occupational Exposure Limit-GERMANYMAK 0.5 ppm (1.3 mg/m3), 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 5 mg/m3, short term exposure limit 5 mg/m3, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 0.5 ppm (1.3 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 2 ppm (5 mg/m3), short term exposure limit 5 ppm (10 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 2 ppm (5 mg/m3);short term exposure limit 5 ppm (10 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 2 ppm (5.2 mg/m3), short term exposure limit 5 ppm (13 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 2 ppm (5 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 2 ppm (5,2 mg/m3); short term exposure limit 5 ppm (13 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 2 mg/m3, MAC(short term exposure limit) 5 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAshort term exposure limit 10 mg/m3, Skin, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 2 ppm (5 mg/m3), ceiling concentration 5 ppm (13 mg/m3), JUN2005
Occupational Exposure Limit-SWITZERLANDceiling concentration 0.5 ppm (1.3 mg/m3), JAN2011
Occupational Exposure Limit-THAILANDtime-weighted average 5 ppm (13 mg/m3), JAN1993
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 5 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 5 ppm (13 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 5 ppm (13 mg/m3), JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 5 ppm (13 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 5 ppm (13 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 5 ppm (13 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 5 ppm (13 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SULFUR DIOXIDE-air10H time-weighted average 2 ppm;short term exposure limit 5 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 70860; Number of Industries 59; Total Number of Facilities 2465; Number of Occupations 58; Total Number of Employees Exposed 55033; Total Number of Female Employees Exposed 8990
National Occupational Hazard Survey 1974Hazard Code 70860; Number of Industries 85; Total Number of Facilities 6399; Number of Occupations 61; Total Number of Employees Exposed 51398

Status in Federal Agencies

OrganizationReference
ATSDR TOXICOLOGY PROFILE (NTIS** PB/99/122020)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Sulfur dioxide, 6004
OSHA ANALYTICAL METHOD #ID-104 (for impinger)
OSHA ANALYTICAL METHOD #ID200
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