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Registry of Toxic Effects of Chemical Substances (RTECS)

2-Pentanol, 4-methyl-, acetate

RTECS #

SA7525000

CAS #

108-84-9

Updated

September 201

Molecular Weight

144.24

Molecular Formula

C8H16O2

Synonyms

1,3-Dimethylbutyl acetate
1,3-Dimethylbutylester kyseliny octove (Czech)
4-Methyl-2-pentanol, acetate
4-Methyl-2-pentyl acetate
Acetic acid, 1,3-dimethylbutyl ester
MAAC
Methylisoamyl acetate
Methylisobutylcarbinol acetate
Methylisobutylcarbinyl acetate
sec-Hexyl acetate
sec-Hexyl acetate (ACGIH:OSHA)
sek.Isohexylester kyseliny octove (Czech)

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /human 100 ppm/15MJIHTAB 28,262,1946
skin /rabbit 500 mg open irritation test mildUCDS** 7/28/1966

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/human lowest published toxic concentration: 100 ppmOlfaction: Other olfaction effects

Eye: Conjunctiva irritation

Lung, Thorax, or Respiration: Other changes
JIHTAB 28,262,1946
inhalation/rat Lowest published lethal concentration: 2000 ppm/4HUCDS** 7/28/1966
oral/rat lethal dose (50 percent kill): 6160 mg/kgUCDS** 7/28/1966
skin/rabbit lethal dose (50 percent kill): >20 mL/kgAMIHBC 10,61,1954

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 50 ppmDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 50 ppm (300 mg/m3)DTLVS* 3,127,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 50 ppm (295 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 50 ppm (300 mg/m3);KZW 100 ppm (600 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 50 ppm (299 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 50 ppm (300 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 50 ppm (300 mg/m3), short term exposure limit 75 ppm (450 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 50 ppm (300 mg/m3), FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 50 ppm (300 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 50 ppm (300 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 50 ppm (300 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 50 ppm (295 mg/m3), JAN2002
Occupational Exposure Limit-PERUtime-weighted average 50 ppm (295 mg/m3), JUL2005
Occupational Exposure Limit-SWITZERLANDceiling concentration 50 ppm (300 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 300 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 50 ppm (300 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 50 ppm (300 mg/m3), JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 50 ppm (300 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 50 ppm (300 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 50 ppm (300 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 50 ppm (300 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO sec-HEXYL ACETATE-air10H time-weighted average 50 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code T1668; Number of Industries 1; Total Number of Facilities 15; Number of Occupations 1; Total Number of Employees Exposed 145
National Occupational Hazard Survey 1974Hazard Code T1668; Number of Industries 1; Total Number of Facilities 5; Number of Occupations 1; Total Number of Employees Exposed 20

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Esters I, 1450
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