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Registry of Toxic Effects of Chemical Substances (RTECS)

2-Pentanol

RTECS #

SA4900000

CAS #

6032-29-7

Updated

July 2013

Molecular Weight

88.17

Molecular Formula

C5H12O

Synonyms

Isoamyl alcohol, secondary (OSHA)
Methyl propyl carbinol
Pentanol-2
sec-Pentyl alcohol

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 20 mg/24H moderate85JCAE -,197,1986
skin /rabbit 20 mg/24H moderate85JCAE -,197,1986

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lowest published lethal dose: 2130 mg/kgJIHTAB 27,1,1945
oral/rabbit lethal dose (50 percent kill): 2821 mg/kgEye: Corneal damage

Cardiac: Pulse rate decreased with fall in BP

Lung, Thorax, or Respiration: Dyspnea
IMSUAI 41,31,1972
parenteral/frog lowest published lethal dose: 3640 mg/kgPeripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Behavioral: Somnolence (general depressed activity)
AIPTAK 50,296,1935

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-DENMARKtime-weighted average 100 ppm (360 mg/m3), MAY2011
Occupational Exposure Limit-GERMANYMAK 20 ppm (73 mg/m3), 2011
Occupational Exposure Limit-ICELANDtime-weighted average 100 ppm (360 mg/m3), NOV2011
Occupational Exposure Limit-NORWAYtime-weighted average 50 ppm (180 mg/m3), JAN1999
Occupational Exposure Limit-POLANDMAC(time-weighted average) 100 mg/m3, MAC(short term exposure limit) 450 mg/m3, JAN1993
Occupational Exposure Limit-RUSSIAshort term exposure limit 5 mg/m3, Skin, JUN2003
Occupational Exposure Limit-SWITZERLANDMAK-week 20 ppm (73 mg/m3), KZG-week 80 ppm (292 mg/m3), JAN2011
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 100 ppm (360 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 100 ppm (360 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 100 ppm (360 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 100 ppm (360 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ISOAMYL ALCOHOL, sec-air10H time-weighted average 100 ppm;short term exposure limit 125 ppmNIOSH* DHHS #92-100,1992

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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