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Registry of Toxic Effects of Chemical Substances (RTECS)

Germane

RTECS #

LY4900000

CAS #

7782-65-2

Updated

September 201

Molecular Weight

76.63

Molecular Formula

GeH4

Synonyms

Germanium hydride
Germanium tetrahydride
Germanium tetrahydride (ACGIH)
Monogermane

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/guinea pig lethal concentration (50 percent kill): 260 mg/m3/4HBrain and Coverings: Other degenerative changesVCVN1* -,400,1988
inhalation/mouse Lowest published lethal concentration: 2000 mg/m3/2HBehavioral: Convulsions or effect on seizure threshold

Nutritional and Gross Metabolic: Body temperature decrease		HBTME* -,557,2007
inhalation/mouse lethal concentration (50 percent kill): 1380 mg/m3Behavioral: Excitement

Behavioral: Ataxia

Behavioral: Muscle contraction or spasticity		GTPZAB 18(2),56,1974
inhalation/rat lethal concentration (50 percent kill): 1380 mg/m3Behavioral: Coma

Brain and Coverings: Other degenerative changes		VCVN1* -,400,1988
inhalation/rat Lowest published lethal concentration: 2000 mg/m3/4HBehavioral: Convulsions or effect on seizure threshold

Nutritional and Gross Metabolic: Body temperature decrease		HBTME* -,557,2007
oral/mouse lethal dose (50 percent kill): 1250 mg/kgBehavioral: Excitement

Behavioral: Ataxia

Behavioral: Muscle contraction or spasticity		GTPZAB 18(2),56,1974

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 13 mg/m3/4H/30D- intermittentBrain and Coverings: Changes in circulation

Brain and Coverings: Other degenerative changes		VCVN1* -,400,1988

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.2 ppmDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWHBTME* ,557,2007

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.2 ppm (0.6 mg/m3)DTLWS* 3,20,1973
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.2 ppm (0.63 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 0.2 ppm (0.6 mg/m3);KZW 0.4 ppm (1.2 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 0.2 ppm (0.64 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.2 ppm (0.6 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDshort term exposure limit 0.2 ppm (0.64 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 0.2 ppm (0.6 mg/m3), FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 0.2 ppm (0.6 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 0.2 ppm (0.6 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.2 ppm (0.6 mg/m3);short term exposure limit 0.6 ppm (1.8 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.2 ppm (0.63 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.2 ppm (0.6 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 0,2 ppm (0,63 mg/m3), JUL2005
Occupational Exposure Limit-RUSSIAshort term exposure limit 5 mg/m3, JUN2003
Occupational Exposure Limit-SWITZERLANDMAK-week 0.2 ppm (0.6 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.6 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.2 ppm (0.64 mg/m3);short term exposure limit 0.6 ppm (1.9 mg/m3), OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO GERMANIUM TETRAHYDRIDE-air10H time-weighted average 0.2 ppmNIOSH* DHHS #92-100,1992

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY

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