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Registry of Toxic Effects of Chemical Substances (RTECS)

Ethane, 1,2-dichloro-1,1,2,2-tetrafluoro-

RTECS #

KI1101000

CAS #

76-14-2

Updated

September 201

Molecular Weight

170.92

Molecular Formula

C2Cl2F4

Synonyms

1,1,2,2-Tetrafluoro-1,2-dichloroethane
1,2-Dichloro-1,1,2,2-tetrafluoroethane
Arcton 114
Arcton 33
Cryofluoran
Cryofluorane
Dichlorotetrafluoroethane
Dichlorotetrafluoroethane (ACGIH:OSHA)
Ethane, 1,2-dichlorotetrafluoro-
F 114
FC 114
Fluorane 114
Fluorocarbon 114
Freon 114
Frigen 114
Frigiderm
Genetron 114
Genetron 316
Halocarbon 114
Ledon 114
Propellant 114
R 114
sym-Dichlorotetrafluoroethane
Ucon 114

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/Dog lowest published toxic concentration: 1444000 mg/m3/8HBehavioral: Convulsions or effect on seizure thresholdVCVGH* -,639,1990
inhalation/guinea pig Lethal concentration: >20 pph/8HJOCMA7 4,262,1962
inhalation/mouse lethal concentration (50 percent kill): 70 pph/30MEJTXAZ 9,385,1976
inhalation/rabbit lethal concentration (50 percent kill): 75 pph/30MEJTXAZ 9,385,1976
inhalation/rat lethal concentration (50 percent kill): 72 pph/30MEJTXAZ 9,385,1976
oral/rat Lethal dose: >2250 mg/kgNTIS** OTS0520424

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 1000 ppmDTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWENTOX* -,384,2005

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 1000 ppm (6990 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 1000 ppm (7000 mg/m3);KZW 2000 ppm (14000 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 1000 ppm (7092 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 500 ppm (3500 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 1000 ppm (7100 mg/m3), short term exposure limit 1300 ppm (9200 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 1000 ppm (7000 mg/m3), FEB2006
Occupational Exposure Limit-GERMANYMAK 1000 ppm (7100 mg/m3), 2011
Occupational Exposure Limit-HUNGARYProhibited in Hungary, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 500 ppm (3500 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 1000 ppm (7000 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 1000 ppm (7000 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 1000 ppm (6990 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 500 ppm (3500 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 1000 ppm (6991 mg/m3); short term exposure limit 1250 ppm (8739 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 5000 mg/m3, MAC(short term exposure limit) 8750 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAshort term exposure limit 3000 mg/m3, JUN2003
Occupational Exposure Limit-SWITZERLANDMAK-week 1000 ppm (7000 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 7130 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 1000 ppm (7000 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 1000 ppm (7000 mg/m3), JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 1000 ppm (7110 mg/m3);short term exposure limit 1250 ppm (8890 mg/m3), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 1000 ppm (7000 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 1000 ppm (7000 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 1000 ppm (7000 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 1000 ppm (7000 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO DICHLOROTETRAFLUOROETHANE-air10H time-weighted average 1000 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code T1293; Number of Industries 10; Total Number of Facilities 1140; Number of Occupations 32; Total Number of Employees Exposed 59867; Total Number of Female Employees Exposed 45860
National Occupational Hazard Survey 1974Hazard Code T1293; Number of Industries 2; Total Number of Facilities 38; Number of Occupations 2; Total Number of Employees Exposed 38

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: 1,2-Dichlorotetrafluoroethane, 1018
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