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Registry of Toxic Effects of Chemical Substances (RTECS)

Decaborane(14)

RTECS #

HD1400000

CAS #

17702-41-9; 1304-02-5

Updated

September 201

Molecular Weight

122.24

Molecular Formula

B10H14

Synonyms

Boron hydride (B10H14)
Decaborane
Decaborane (ACGIH:OSHA)
Decaborane(14) fumes
nido-Decaborane(14)
Tetradecahydrodecaborane

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
eye/rabbit lowest published toxic dose: 0.01 mg/kg/5MEye: Conjunctiva irritation

Eye: Corneal damage		VCVN1* -,201,1988
inhalation/mouse lethal concentration (50 percent kill): 30 mg/m3VCVN1* -,199,1988
inhalation/mouse lethal concentration (50 percent kill): 12 ppm/4HEye: Other eye effects

Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia		NTIS** AD224-006
inhalation/rat lethal concentration (50 percent kill): 110 mg/m3/4HVCVN1* -,199,1988
inhalation/rat lethal concentration (50 percent kill): 46 ppm/4HBehavioral: Convulsions or effect on seizure threshold

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes		AMIHAB 17,362,1958
intraperitoneal/mouse lethal dose (50 percent kill): 33 mg/kgBehavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Lung, Thorax, or Respiration: Cyanosis		AMIHAB 11,132,1955
intraperitoneal/mouse lethal dose (50 percent kill): 33 mg/kgBehavioral: ComaVCVN1* -,199,1988
intraperitoneal/rabbit lethal dose (50 percent kill): 28 mg/kgBehavioral: ComaVCVN1* -,199,1988
intraperitoneal/rabbit lethal dose (50 percent kill): 28 mg/kgAMIHBC 8,335,1953
intraperitoneal/rat lethal dose (50 percent kill): 23 mg/kgAMIHBC 8,335,1953
intraperitoneal/rat lethal dose (50 percent kill): 23 mg/kgBehavioral: ComaVCVN1* -,199,1988
oral/mouse lethal dose (50 percent kill): 41 mg/kgEye: Corneal damage

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Cyanosis		AMIHAB 11,132,1955
oral/rat lethal dose (50 percent kill): 64 mg/kgMLSR** #8,1951
oral/rat lethal dose (50 percent kill): 64 mg/kgBehavioral: ComaVCVN1* -,199,1988
skin/cat lethal dose (50 percent kill): 126 mg/kgBehavioral: Convulsions or effect on seizure threshold

Liver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)		STGNBT -,60,1999
skin/cat lethal dose (50 percent kill): 126 mg/kg/4HVCVN1* -,201,1988
skin/guinea pig lethal dose (50 percent kill): 158 mg/kg/4HVCVN1* -,201,1988
skin/guinea pig lethal dose (50 percent kill): 158 mg/kgBehavioral: Convulsions or effect on seizure threshold

Liver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)		STGNBT -,60,1999
skin/mouse lethal dose (50 percent kill): 317 mg/kgBehavioral: Convulsions or effect on seizure threshold

Liver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)		STGNBT -,60,1999
skin/mouse lethal dose (50 percent kill): 317 mg/kg/4HVCVN1* -,201,1988
skin/rabbit lethal dose (50 percent kill): 71 mg/kgBehavioral: Altered sleep time (including change in righting reflex)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea		AMIHAB 11,132,1955
skin/rabbit lethal dose (50 percent kill): 57 mg/kg/4HVCVN1* -,201,1988
skin/rat lethal dose (50 percent kill): 740 mg/kg/4HVCVN1* -,201,1988
skin/rat lethal dose (50 percent kill): 740 mg/kgPeripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Dyspnea		AMIHAB 11,132,1955

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lowest published toxic concentration: 22 mg/m3/5H/10D- intermittentRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldVCVN1* -,199,1988
inhalation/rat lowest published toxic concentration: 22 mg/m3/5H/135D- intermittentRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldVCVN1* -,199,1988
oral/rabbit lowest published toxic dose: 1050 µg/kg/21D- intermittentBrain and Coverings: Other degenerative changes

Vascular: Other changes

Lung, Thorax, or Respiration: Other changes		STGNBT -,60,1999
oral/rat lowest published toxic dose: 9100 µg/kg/26W- intermittentBrain and Coverings: Other degenerative changes

Behavioral: Somnolence (general depressed activity)

Blood: Pigmented or nucleated red blood cells		STGNBT -,60,1999

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.05 ppm;short term exposure limit 0.15 ppm (skin)DTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.05 ppm (0.3 mg/m3) (skin)DTLVS* 3,68,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 005 ppm (0.25 mg/m3), short term exposure limit 0.15 ppm (0.75 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 0.05 ppm (0.3 mg/m3);KZW 0.1 ppm (0.6 mg/m3), skin, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 0.05 ppm (0.25 mg/m3), MAR2002
Occupational Exposure Limit-BELGIUMshort term exposure limit 0.15 ppm (0.76 mg/m3), Skin, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.05 ppm (0.3 mg/m3), skin, MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 0.05 ppm (0.25 mg/m3), short term exposure limit 0.15 ppm (0.76 mg/m3), skin, NOV2011
Occupational Exposure Limit-FRANCEVME 0.05 ppm (0.3 mg/m3), Skin, FEB2006
Occupational Exposure Limit-GERMANYMAK 0.05 ppm (0.25 mg/m3), 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 0.3 mg/m3, short term exposure limit 0.3 mg/m3, Skin, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 0.05 ppm (0.3 mg/m3), skin, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 0.05 ppm (0.3 mg/m3), short term exposure limit 0.15 ppm (0.9 mg/m3), skin, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.05 ppm (0.3 mg/m3);short term exposure limit 0.15 ppm (skin), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.05 ppm (0.25 mg/m3), skin, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.05 ppm (0.3 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 0.05 ppm (0.25 mg/m3); short term exposure limit 0.15 ppm (0.75 mg/m3), JUL2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.05 ppm (0.25 mg/m3), KZG-week 0.1 ppm (0.5 mg/m3), skin, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.3 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.05 ppm (0.3 mg/m3), Skin, JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 0.05 ppm (0.3 mg/m3), Skin, JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.05 ppm (0.3 mg/m3) (skin)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.05 ppm (0.3 mg/m3) (skin)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 0.05 ppm (0.3 mg/m3) (skin)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 0.05 ppm (0.3 mg/m3) (skin)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO DECABORANE-air10H time-weighted average 0.05 ppm (Sk);short term exposure limit 0.15 ppm (Sk)NIOSH* DHHS #95-121,1995

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
On EPA IRIS database

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