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Registry of Toxic Effects of Chemical Substances (RTECS)

Carbonyl fluoride

RTECS #

FG6125000

CAS #

353-50-4

Updated

September 201

Molecular Weight

66.01

Molecular Formula

CF2O

Synonyms

Carbon difluoride oxide
Carbon fluoride oxide
Carbon oxyfluoride
Carbonic difluoride (9CI)
Carbonyl difluoride
Carbonyl fluoride (ACGIH)
Difluoroformaldehyde
Difluorooxomethane
Fluophosgene
Fluoroformyl fluoride
Fluorophosgene
RCRA waste number U033

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): 360 ppm/1HLung, Thorax, or Respiration: Consolidation

Lung, Thorax, or Respiration: Fibrosis (interstitial)

Liver: Fatty liver degeneration		AIHAAP 29,41,1968

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 2 ppm;short term exposure limit 5 ppmDTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 2.5 mg(F)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWREPTED 29,1,2010

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2 ppm (5 mg/m3), short term exposure limit 5 ppm (13 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2.5 mg(F)/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 2 ppm (5.5 mg/m3), short term exposure limit 5 ppm (13 mg/m3), MAR2002
Occupational Exposure Limit-BELGIUMtime-weighted average 2.5 mg(F)/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 2 ppm (6 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDshort term exposure limit 2 ppm (5.5 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 2 ppm (5 mg/m3), FEB2006
Occupational Exposure Limit-HUNGARYtime-weighted average 2.5 mg(F)/m3, short term exposure limit 10 mg(F)/m3, Skin, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 2 ppm (6 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 2 ppm (5 mg/m3), short term exposure limit 5 ppm (15 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 2 ppm (5 mg/m3);short term exposure limit 5 ppm (15 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 2 ppm (5.4 mg/m3); short term exposure limit 5 ppm (13 mg/m3), JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 2 ppm (5 mg/m3), JAN1999
Occupational Exposure Limit-PERUtime-weighted average 2 ppm (5,4 mg/m3); short term exposure limit 5 ppm (13,5 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 1 mg(HF)/m3, MAC(short term exposure limit) 3 mg(HF)/m3, JAN1999
Occupational Exposure Limit-SWITZERLANDMAK-week 2 ppm (5 mg/m3), JAN2011

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CARBONYL FLUORIDE-air10H time-weighted average 2 ppm;short term exposure limit 5 ppmNIOSH* DHHS #95-121,1995

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database

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