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Registry of Toxic Effects of Chemical Substances (RTECS)

Carbon Black

RTECS #

FF5800000

CAS #

1333-86-4

Updated

September 201

Molecular Weight

N/R

Molecular Formula

N/R

Synonyms

Acetylene Black
Aroflow
Arogen
Arotone
Arovel
Arrow
Atlantic
Black pearls
C.I. 77266
C.I. Pigment Black 6
C.I. Pigment Black 7
Cancarb
Carbodis
Carbolac
Carbolac 1
Carbomet
Carbon Black (ACGIH:OSHA)
Carbon Black BV and V
Carbon black, acetylene
Carbon black, channel
Carbon black, furnace
Carbon black, lamp
Carbon black, thermal
Channel Black
CK3
Collocarb
Colloidal-carbon
Columbia carbon
Conductex 900
Continex
Corax A
Corax P
Croflex
Crolac
Degussa
Delussa Black FW
Durex O
Eagle Germantown
ELF 78
Elftex
Essex
Excelsior
Explosion Acetylene Black
Explosion Black
Farbruss
Fecto
Flamruss
Furnal
Furnex
Furnex N 765
Gas-furnace black
Gastex
Huber
Humenegro
Impingement Black
Ketjenblack EC
Kosmink
Kosmobil
Kosmolak
Kosmos
Kosmotherm
Kosmovar
Magecol
Metanex
Micronex
Miike 20
Modulex
Mogul
Mogul L
Molacco
Monarch 1300
Neo Spectra Beads AG
Neo-Spectra Mark II
Neotex
Oil-furnace Black
P 33 (carbon black)
P1250
P68
Peach black
Pelletex
Philblack
Philblack N 550
Philblack N 765
Philblack O
Pigment Black 7
Printex
Printex 60
Raven
Raven 30
Raven 420
Raven 500
Raven 8000
Rebonex
Regal
Regal 300
Regal 330
Regal 400R
Regal 600
Regal 99
Regal SRF
Regent
Royal spectra
Sevacarb
Seval
Shawinigan Acetylene Black
Shell carbon
Special Black 1V & V
Special schwarz
Spheron
Spheron 6
Statex
Statex N 550
Sterling MT
Sterling N 765
Sterling NS
Sterling SO 1
Superba
Super-carbovar
Super-spectra
Texas
Therma-atomic Black
Thermal Acetylene Black
Thermatomic
Thermax
Thermblack
Tinolite
TM 30
Toka Black 4500
Toka Black 5500
Toka Black 8500
Torch Brand
Ucet
Ukarb
United
Velvetex
Vulcan
Witco
Witcoblak No. 100
Wyex

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
DNA adductinhalation/mouse6200 µg/m3/16H/12W- intermittentEMMUEG 16,64,1990
DNA Damagelymphocyte/human16 µg/L/48HEMMUEG 37,155,2001
DNA Damageinhalation/rat50 µg/L/13W- intermittentTXAPA9 190,224,2003
DNA Damageinhalation/rat50 gm/L/13WTOXID9 60,194,2001
mutation in microorganisms/Salmonella typhimurium1 mg/plate (+enzymatic activation step)EVSRBT 27,297,1983

Tumorigenic Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 11600 µg/m3/18H/2Y- intermittentTumorigenic: Carcinogenic by RTECS criteria

Lung, Thorax, or Respiration: Tumors
INHTE5 7,533,1995

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lowest published toxic concentration: 50 mg/m3/6HOlfaction: Other olfaction effectsTOXID9 44,91,2005
inhalation/rat lowest published toxic concentration: 1.66 mg/m3/7HLung, Thorax, or Respiration: Sputum

Blood: Changes in leukocyte (WBC) count

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXAPA9 195,35,2004
inhalation/rat lowest published toxic concentration: 50 mg/m3Olfaction: Other olfaction effects

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 78,436,2004
inhalation/rat lowest published toxic concentration: 7 mg/m3Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 72,289,2003
inhalation/rat lowest published toxic concentration: 229 mg/m3/6HLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 -,306,2008
intratracheal/mouse lowest published toxic dose: 1000 µg/kgLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXAPA9 213,256,2006
intratracheal/rat lowest published toxic dose: 10 mg/kgLung, Thorax, or Respiration: Sputum

Biochemical: Metabolism (intermediary): Other proteins

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXAPA9 207,221,2005
intratracheal/rat lowest published toxic dose: 16 mg/kgLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 44,300,2005
intratracheal/rat lowest published toxic dose: 15 mg/kgLung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)
TOXID9 66,126,2002
intravenous/rat lowest published toxic dose: 10 mg/kg/2MLiver: Changes in liver weight

Blood: Changes in spleen
XENOBH 10,,1980
intravenous/rat lowest published toxic dose: 10 mg/kg/2MBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)BCPCA6 30,,1981
oral/rat lethal dose (50 percent kill): >15400 mg/kgBehavioral: Somnolence (general depressed activity)ATDAEI 15(Suppl 1),S28,1996
skin/rabbit lethal dose (50 percent kill): >3 gm/kgATDAEI 15(Suppl 1),S28,1996

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/hamster lowest published toxic concentration: 7 mg/m3/13W- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 72,288,2003
inhalation/hamster lowest published toxic concentration: 50 mg/m3/6H/13W- intermittentOlfaction: Other olfaction effectsTOXID9 78,436,2004
inhalation/mouse lowest published toxic concentration: 1 mg/m3/13W- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 66,356,2002
inhalation/mouse lowest published toxic concentration: 7 mg/m3/6H/13W- intermittentOlfaction: Other olfaction effects

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 78,436,2004
inhalation/mouse lowest published toxic concentration: 1 mg/m3/13W- intermittentLung, Thorax, or Respiration: Other changes

Lung, Thorax, or Respiration: Changes in lung weight

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 66,356,2002
inhalation/rat lowest published toxic concentration: 50 mg/m3/13W- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Other
TOXID9 60,194,2001
inhalation/rat lowest published toxic concentration: 50 mg/m3/13W- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Other

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 60,194,2001
inhalation/rat lowest published toxic concentration: 7 mg/m3/6H/13W- intermittentOlfaction: Other olfaction effects

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 78,436,2004
inhalation/rat lowest published toxic concentration: 50 mg/m3/6H/90D- intermittentLung, Thorax, or Respiration: Other changesTOXID9 15,46,1995
inhalation/rat lowest published toxic concentration: 1 mg/m3/13W- intermittentLung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 66,356,2002
inhalation/rat lowest published toxic concentration: 1 mg/m3/13W- intermittentLung, Thorax, or Respiration: Other changes

Lung, Thorax, or Respiration: Changes in lung weight

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 66,356,2002
intratracheal/mouse lowest published toxic dose: 20 mg/kg/4D- intermittentLung, Thorax, or Respiration: Sputum

Immunological Including Allergic: Increase in cellular immune response

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXAPA9 209,51,2005
intratracheal/mouse lowest published toxic dose: 4000 µg/kg/4W- intermittentLung, Thorax, or Respiration: Other changes

Immunological Including Allergic: Increase in cellular immune response

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXAPA9 209,51,2005
oral/mouse lowest published toxic dose: 20000 µg/kg/4W- intermittentBrain and Coverings: Other degenerative changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOLED5 163,153,2006
parenteral/mouse lowest published toxic dose: 36 µg/kg/3D- intermittentImmunological Including Allergic: Increase in humoral responseTOXID9 44,93,2005
skin/rat lowest published toxic dose: 11 gm/kg/4W- intermittentBlood: Pigmented or nucleated red blood cells

Liver: Changes in liver weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
NTIS** OTS0534753

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 3 mg/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Confirmed animal carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 65,149,1996
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 33,35,1984
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 33,35,1984
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 65,149,1996
International Agency for Research on Cancer (IARC)Cancer Review:Group 2BIMEMDT 65,149,1996
TOXICOLOGY REVIEWMUREAV 681,241,2009
TOXICOLOGY REVIEWMUTAEX 21,225,2006
TOXICOLOGY REVIEWFEREAC 74,40509,2009
TOXICOLOGY REVIEWMUREAV 727,72,2011
TOXICOLOGY REVIEWMUREAV 727,72,2011

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 3.5 mg/m3DTLVS* 3,38,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 3 mg/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 3.6 mg/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 3.5 mg/m3, carc, MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 3.5 mg/m3, short term exposure limit 7 mg/m3, NOV2011
Occupational Exposure Limit-FRANCEVME 3.5 mg/m3, FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 3.5 mg/m3, NOV2011
Occupational Exposure Limit-JAPANOccupational Exposure Limit 1 mg/m3 (resp. dust), 4 mg/m3 (total dust), 2B carc, MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 3.5 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 3.5 mg/m3;short term exposure limit 7 mg/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 3 mg/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 3.5 mg/m3, JAN1999
Occupational Exposure Limit-PERUtime-weighted average 3,5 mg/m3, JUL2005
Occupational Exposure Limit-RUSSIAshort term exposure limit 4 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 3 mg/m3, JUN2005
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 3.5 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 3.5 mg/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 3.5 mg/m3;short term exposure limit 7 mg/m3, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 3.5 mg/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 3.5 mg/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 3.5 mg/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 3.5 mg/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CARBON BLACK-air10H Carcinogen time-weighted average 3.5 mg/m3 in pres. of PAHsNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code M0647; Number of Industries 376; Total Number of Facilities 108610; Number of Occupations 206; Total Number of Employees Exposed 1728518; Total Number of Female Employees Exposed 369253
National Occupational Exposure Survey 1983Hazard Code X7126; Number of Industries 1; Total Number of Facilities 22; Number of Occupations 1; Total Number of Employees Exposed 129; Total Number of Female Employees Exposed 65
National Occupational Hazard Survey 1974Hazard Code M0647; Number of Industries 159; Total Number of Facilities 19312; Number of Occupations 88; Total Number of Employees Exposed 172738

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Carbon black, 5000
OSHA ANALYTICAL METHOD #ID196
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