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Registry of Toxic Effects of Chemical Substances (RTECS)

Calcium carbonate

RTECS #

EV9580000

CAS #

1317-65-3

Updated

July 2013

Molecular Weight

100.09

Molecular Formula

CO3·Ca

Synonyms

Agricultural limestone
Agstone
Bell mine pulverized limestone
Calcium carbonate (ACGIH:OSHA)
Calcium carbonate, dust
Chalk
Domolite
Franklin
Limestone (OSHA)
Lithograpic stone
Marble (OSHA)
Natural calcium carbonate
Portland stone
Sohnhofen stone

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intravenous/rat lowest published toxic dose: 30 mg/kgVascular: BP lowering not characterized in autonomic section

Lung, Thorax, or Respiration: Changes in lung weight

Blood: Other changes		TOXID9 -,189,2009

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/rat lowest published toxic concentration: 84 mg/m3/4H/40W- intermittentLung, Thorax, or Respiration: Fibrosis (interstitial)

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes		VCVN1* -,114,1988
inhalation/rat lowest published toxic concentration: 250 mg/m3/2H/24W- intermittentLung, Thorax, or Respiration: Fibrosis, focal (pneumoconiosis)VCVN1* -,115,1988

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWBPCEM* 17,237,2003
TOXICOLOGY REVIEWBPRCG* 21,849,2007

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARDNUISANCE PARTICULATESDTLWS* 3,12,1973
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-BELGIUMtime-weighted average 10 mg/m3, MAR2002
Occupational Exposure Limit-HUNGARYtime-weighted average 10 mg/m3, SEP2000
Occupational Exposure Limit-JAPANOccupational Exposure Limit 2 mg/m3 (resp. dust), 84 mg/m3 (total dust), MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 10 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 10 mg/m3;short term exposure limit 20 mg/m3 (inhalable), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 10 mg/m3 (inspirable dust), JAN2002
Occupational Exposure Limit-POLANDMAC(time-weighted average) dust 10 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAshort term exposure limit 6 mg/m3, JUN2003
Occupational Exposure Limit-SWITZERLANDMAK-week 3 mg/m3, resp, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 10 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 10 mg/m3 (inhal. dust), OCT2007
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 4 mg/m3 (resp. dust), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 15 mg/m3, total dustCFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 5 mg/m3, respirable fractionCFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 15 mg/m3, total dustCFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 5 mg/m3, respirable fractionCFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 15 mg/m3, total dustCFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 5 mg/m3, respirable fractionCFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CALCIUM CARBONATE, respirable-air10H time-weighted average 5 mg/m3NIOSH* DHHS #95-121,1995
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CALCIUM CARBONATE, total dust-air10H time-weighted average 10 mg/m3NIOSH* DHHS #95-121,1995
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO LIMESTONE, respirable fraction-air10H time-weighted average 5 mg/m3NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO LIMESTONE, total dust-air10H time-weighted average 10 mg/m3NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO MARBLE, respirable fraction-air10H time-weighted average 5 mg/m3NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO MARBLE, total dust-air10H time-weighted average 10 mg/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code M1525; Number of Industries 164; Total Number of Facilities 31577; Number of Occupations 138; Total Number of Employees Exposed 533341; Total Number of Female Employees Exposed 36245
National Occupational Exposure Survey 1983Hazard Code X3265; Number of Industries 51; Total Number of Facilities 4765; Number of Occupations 57; Total Number of Employees Exposed 79861; Total Number of Female Employees Exposed 4247
National Occupational Hazard Survey 1974Hazard Code M1525; Number of Industries 76; Total Number of Facilities 9388; Number of Occupations 85; Total Number of Employees Exposed 135016

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

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