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How Hemophilia is Inherited

The following examples show how the hemophilia gene can be inherited. It is important to note that in one-third of people with hemophilia, there is no family history of the disorder.

  1. In this example, the mother is a carrier of the hemophilia gene, and the father does not have hemophilia.
    • There is a 50% chance that each son will have hemophilia.
    • There is a 50% chance that each daughter will be a carrier of the hemophilia gene.

Image showing if the mother is a carrier of the hemophilia gene, and the father does not have hemophilia, there is a 50% chance that each son will have hemophilia, there is a 50% chance that each daughter will be a carrier of the hemophilia gene.

  1. In this example, the father has hemophilia, and the mother does not carry the hemophilia gene.
    • All daughters will carry the hemophilia gene.
    • No sons will have hemophilia.

Image: In this example, the father has hemophilia, and the mother does not carry the hemophilia gene. All daughters will carry the hemophilia gene. No sons will have hemophilia.

  1. In this example, the father does not have hemophilia, and the mother does not carry the hemophilia gene.
    • None of the children (daughters or sons) will have hemophilia or carry the gene.

Image: In this example, the father does not have hemophilia, and the mother does not carry the hemophilia gene. None of the children (daughters or sons) will have hemophilia or carry the gene

References

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