Surveillance for Viral Hepatitis – United States, 2015

Entire report in a printable format[PDF – 2MB – 73 pages]

Investigation of Healthcare-associated Outbreak Cases

Table 1.1 Hepatitis C Outbreaks by Setting ― United States, 2015

Hepatitis A virus

Index-HepA

PAGE	DESCRIPTION
Table 2.1	Reported cases of hepatitis A, nationally and by state or jurisdiction― United States, 2011-2015
Table 2.2	Select Clinical Characteristics of Hepatitis A Cases Reported in the United States, 2015
Table 2.3	Number and rate of hepatitis A-related deaths, by demographic characteristics and year — United States, 2011–2015
Figure 2.1	Reported number of hepatitis A — United States, 2000–2015
Figure 2.2	Incidence of hepatitis A, by age group — United States, 2000–2015
Figure 2.3	Incidence of hepatitis A, by sex — United States, 2000–2015
Figure 2.4	Incidence of hepatitis A, by race/ethnicity — United States, 2000–2015
Figure 2.5	Availability of information on risk exposures/behaviors associated with hepatitis A — United States, 2015
Figure 2.6a	Hepatitis A reports, by risk exposure/behavior — United States, 2015
Figure 2.6b	Hepatitis A reports, by risk exposure/behavior — United States, 2015
Map 2.1	2015 State Acute Hepatitis A Incidence Compared to Healthy People 2020 National Goal

Hepatitis A virus

Table 2.1. Reported cases of hepatitis A, nationally and by state or jurisdiction ― United States, 2011–2015

State	2011		2012		2013		2014		2015
State	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*
Alabama	8	0.2	19	0.4	10	0.2	15	0.3	23	0.5
Alaska	4	0.6	1	0.1	1	0.1	1	0.1	4	0.5
Arizona	77	1.2	93	1.4	66	1.0	29	0.4	54	0.8
Arkansas	3	0.1	8	0.3	9	0.3	2	0.1	10	0.3
California	186	0.5	209	0.5	255	0.7	142	0.4	179	0.5
Colorado	21	0.4	28	0.5	51	1.0	23	0.4	25	0.5
Connecticut	18	0.5	23	0.6	19	0.5	23	0.6	9	0.3
Delaware	2	0.2	9	1.0	4	0.4	1	0.1	2	0.2
District of Columbia	U	U	U	U	U	U	U	U	U	U
Florida	87	0.5	87	0.5	115	0.6	90	0.5	108	0.5
Georgia	27	0.3	46	0.5	36	0.4	24	0.2	30	0.3
Hawaii	8	0.6	5	0.4	16	1.1	5	0.4	6	0.4
Idaho	6	0.4	11	0.7	8	0.5	7	0.4	9	0.5
Illinois	73	0.6	67	0.5	79	0.6	82	0.6	57	0.4
Indiana	24	0.4	11	0.2	32	0.5	20	0.3	19	0.3
Iowa	8	0.3	7	0.2	17	0.6	12	0.4	16	0.5
Kansas	4	0.1	15	0.5	11	0.4	7	0.2	7	0.2
Kentucky	10	0.2	25	0.6	24	0.5	19	0.4	16	0.4
Louisiana	5	0.1	7	0.2	14	0.3	5	0.1	5	0.1
Maine	6	0.5	9	0.7	10	0.8	8	0.6	8	0.6
Maryland	26	0.4	28	0.5	29	0.5	27	0.5	19	0.3
Massachusetts	39	0.6	40	0.6	43	0.6	43	0.6	34	0.5
Michigan	70	0.7	100	1.0	83	0.8	45	0.5	51	0.5
Minnesota	27	0.5	29	0.5	32	0.6	19	0.3	21	0.4
Mississippi	7	0.2	11	0.4	5	0.2	3	0.1	2	0.1
Missouri	13	0.2	20	0.3	8	0.1	20	0.3	9	0.1
Montana	3	0.3	6	0.6	6	0.6	5	0.5	2	0.2
Nebraska	5	0.3	16	0.9	13	0.7	9	0.5	6	0.3
Nevada	5	0.2	10	0.4	19	0.7	5	0.2	11	0.4
New Hampshire	0	0.0	6	0.5	9	0.7	5	0.4	2	0.2
New Jersey	79	0.9	60	0.7	68	0.8	59	0.7	59	0.7
New Mexico	7	0.3	10	0.5	20	1.0	8	0.4	6	0.3
New York	113	0.6	111	0.6	167	0.8	84	0.4	123	0.6
North Carolina	31	0.3	34	0.3	46	0.5	38	0.4	45	0.4
North Dakota	0	0.0	2	0.3	9	1.2	9	1.2	5	0.7
Ohio	39	0.3	36	0.3	59	0.5	32	0.3	36	0.3
Oklahoma	11	0.3	12	0.3	14	0.4	17	0.4	11	0.3
Oregon	11	0.3	9	0.2	29	0.7	13	0.3	28	0.7
Pennsylvania	60	0.5	62	0.5	53	0.4	48	0.4	43	0.3
Rhode Island	8	0.8	3	0.3	4	0.4	8	0.8	4	0.4
South Carolina	11	0.2	6	0.1	14	0.3	6	0.1	16	0.3
South Dakota	2	0.2	0	0.0	4	0.5	3	0.4	2	0.2
Tennessee	23	0.4	23	0.4	20	0.3	12	0.2	14	0.2
Texas	138	0.5	134	0.5	109	0.4	124	0.5	147	0.5
Utah	8	0.3	4	0.1	12	0.4	8	0.3	8	0.3
Vermont	6	1.0	2	0.3	7	1.1	1	0.2	3	0.5
Virginia	30	0.4	49	0.6	36	0.4	27	0.3	50	0.6
Washington	31	0.5	29	0.4	45	0.6	26	0.4	26	0.4
West Virginia	8	0.4	8	0.4	4	0.2	12	0.6	8	0.4
Wisconsin	8	0.1	21	0.4	37	0.6	7	0.1	9	0.2
Wyoming	2	0.4	1	0.2	0	0.0	1	0.2	3	0.5
U.S.	1398	0.4	1562	0.5	1781	0.6	1239	0.4	1390	0.4

Source: CDC, National Notifiable Diseases Surveillance System.
*Rate per 100,000 population.
U=No data available for reporting.

Table 2.2. Select Clinical Characteristics of Hepatitis A Cases* Reported in the United States, 2015

Clinical characteristic	Availability of valid data† for clinical characteristic		Cases with clinical characteristic§
Clinical characteristic	No.	%	No.	%
Jaundice	865	62.2	541	62.5
Hospitalized for hepatitis A	870	62.6	411	47.2
Died from hepatitis A	801	57.6	8	1

Source: CDC, National Notifiable Diseases Surveillance System.
*A total of 1,390 hepatitis A cases were reported during 2015.
†Case reports for which questions regarding clinical characteristics were answered with “yes” or “no.” Reports with any other response were excluded.
§Numbers and percentages represent only those case reports for which data regarding clinical characteristics were available; numbers likely are underestimates.

Table 2.3. Number and rate* of hepatitis A-related deaths^†, by demographic characteristics and year — United States, 2011–2015

Demographic characteristic		2011		2012^§		2013		2014		2015
Demographic characteristic		No.	Rate	No.	Rate	No.	Rate	No.	Rate	No.	Rate
Age Group (years)	0–34	0	0.00	2	0.00	2	0.00	0	0.00	1	0.00
	35–44	1	0.00	5	0.01	2	0.00	4	0.01	4	0.01
	45–54	11	0.02	12	0.03	13	0.03	7	0.02	6	0.01
	55–64	16	0.04	23	0.06	30	0.08	28	0.07	19	0.05
	65–74	12	0.05	17	0.07	19	0.08	19	0.07	16	0.06
	≥75	29	0.15	18	0.09	14	0.07	18	0.09	21	0.10
Race/ ethnicity^§	White NH (non-Hispanic)	44	0.02	51	0.02	63	0.02	51	0.02	45	0.02
	Black NH	10	0.03	8	0.02	6	0.01	11	0.03	7	0.02
	Hispanic	6	0.02	8	0.02	8	0.02	10	0.02	10	0.03
	Asian/Pacific Islander	8	0.06	7	0.05	3	0.02	2	0.01	4	0.02
	American Indian/Alaska Native	1	0.04	2	0.08	0	0.00	2	0.10	1	0.04
Sex	Male	37	0.02	46	0.03	50	0.03	42	0.02	38	0.02
Sex	Female	32	0.02	31	0.02	30	0.01	34	0.02	29	0.02
Overall		69	0.02	77	0.02	80	0.02	76	0.02	67	0.02

Source: CDC, National Vital Statistics System.
*Rates for race, sex, and overall total are age-adjusted per 100,000 U.S. standard population in 2000.
†Cause of death is defined as the underlying cause of death or one of the multiple causes of death and is based on the International Classification of Diseases, 10th Revision (ICD-10) codes B15 (hepatitis A).
^§One death in 2012 is not represented under the race/ethnicity category due to missing data.

All seven figure slides in PowerPoint[PPT – 827 KB]

Hepatitis B virus

Index-HepB

PAGE	DESCRIPTION
Table 3.1	Reported cases of acute hepatitis B, nationally and by state or jurisdiction ― United States, 2011–2015
Table 3.2	Select Clinical Characteristics of Acute Hepatitis B Cases Reported in the United States, 2015
Table 3.3	Number of newly reported case reports of confirmed chronic hepatitis B submitted by states or jurisdictions, 2015
Table 3.4	Reported cases of chronic hepatitis B, by demographic characteristics and laboratory tests — Enhanced Viral Hepatitis Surveillance Sites, 2015
Table 3.5	Number and rate of hepatitis B-related deaths, by demographic characteristics and year— United States, 2011–2015
Table 3.6	Number of newly reported case reports of perinatal hepatitis B submitted by states and jurisdictions, 2015
Figure 3.1	Reported number of acute hepatitis B — United States, 2000–2015
Figure 3.2	Incidence of acute hepatitis B, by age group — United States, 2000–2015
Figure 3.3	Incidence of acute hepatitis B, by sex — United States, 2000–2015
Figure 3.4	Incidence of acute hepatitis B, by race/ethnicity — United States, 2000–2015
Figure 3.5	Availability information on risk exposures/behaviors associated with acute hepatitis B — United States, 2015
Figure 3.6a	Acute hepatitis B reports, by risk exposure/behavior — United States, 2015
Figure 3.6b	Acute hepatitis B reports, by risk exposure/behavior — United States, 2015
Map 3.1	2015 State Acute Hepatitis B Incidence Compared to Healthy People 2020 National Goal

Hepatitis B virus

Table 3.1. Reported cases of acute hepatitis B, nationally and by state or jurisdiction ― United States, 2011–2015

State	2011		2012		2013		2014		2015
State	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*
Alabama	119	2.5	79	1.6	90	1.9	117	2.4	101	2.1
Alaska	3	0.4	1	0.1	1	0.1	3	0.4	3	0.4
Arizona	14	0.2	14	0.2	28	0.4	31	0.5	25	0.4
Arkansas	57	1.9	74	2.5	50	1.7	28	0.9	36	1.2
California	157	0.4	136	0.4	138	0.4	110	0.3	160	0.4
Colorado	23	0.4	24	0.5	24	0.5	29	0.5	28	0.5
Connecticut	19	0.5	15	0.4	8	0.2	9	0.3	6	0.2
Delaware	13	1.4	11	1.2	14	1.5	8	0.9	8	0.8
District of Columbia	U	U	U	U	U	U	U	U	U	U
Florida	213	1.1	247	1.3	323	1.7	313	1.6	432	2.1
Georgia	142	1.4	109	1.1	104	1.0	103	1.0	119	1.2
Hawaii	6	0.4	5	0.4	4	0.3	6	0.4	14	1.0
Idaho	2	0.1	5	0.3	13	0.8	6	0.4	8	0.5
Illinois	85	0.7	86	0.7	94	0.7	58	0.5	55	0.4
Indiana	70	1.1	90	1.4	101	1.5	126	1.9	133	2.0
Iowa	15	0.5	13	0.4	11	0.4	9	0.3	16	0.5
Kansas	15	0.5	9	0.3	11	0.4	11	0.4	19	0.7
Kentucky	151	3.5	180	4.1	214	4.9	164	3.7	162	3.7
Louisiana	62	1.4	44	1.0	82	1.8	87	1.9	87	1.9
Maine	8	0.6	9	0.7	11	0.8	12	0.9	9	0.7
Maryland	62	1.1	52	0.9	43	0.7	40	0.7	40	0.7
Massachusetts	67	1.0	75	1.1	71	1.1	30	0.4	25	0.4
Michigan	91	0.9	81	0.8	53	0.5	50	0.5	56	0.6
Minnesota	20	0.4	17	0.3	19	0.4	16	0.3	19	0.3
Mississippi	57	1.9	78	2.6	55	1.8	48	1.6	50	1.7
Missouri	60	1.0	48	0.8	61	1.0	31	0.5	35	0.6
Montana	0	0.0	2	0.2	4	0.4	0	0.0	4	0.4
Nebraska	12	0.7	10	0.5	9	0.5	8	0.4	3	0.2
Nevada	29	1.1	28	1.0	29	1.0	21	0.7	25	0.9
New Hampshire	3	0.2	4	0.3	2	0.2	4	0.3	0	0.0
New Jersey	73	0.8	70	0.8	65	0.7	77	0.9	85	0.9
New Mexico	10	0.5	3	0.1	3	0.1	2	0.1	2	0.1
New York	134	0.7	113	0.6	117	0.6	95	0.5	80	0.4
North Carolina	109	1.1	73	0.7	75	0.8	100	1.0	165	1.6
North Dakota	0	0.0	0	0.0	0	0.0	0	0.0	2	0.3
Ohio	90	0.8	178	1.5	225	1.9	171	1.5	409	3.5
Oklahoma	100	2.6	79	2.1	40	1.0	57	1.5	37	0.9
Oregon	32	0.8	25	0.6	32	0.8	32	0.8	24	0.6
Pennsylvania	84	0.7	63	0.5	43	0.3	68	0.5	61	0.5
Rhode Island	U	U	U	U	U	U	U	U	U	U
South Carolina	39	0.8	37	0.8	58	1.2	37	0.8	30	0.6
South Dakota	2	0.2	2	0.2	5	0.6	3	0.4	2	0.2
Tennessee	192	3.0	240	3.7	262	4.0	232	3.5	243	3.7
Texas	204	0.8	170	0.7	142	0.5	122	0.5	159	0.6
Utah	10	0.4	13	0.5	5	0.2	11	0.4	10	0.3
Vermont	0	0.0	2	0.3	2	0.3	4	0.6	3	0.5
Virginia	84	1.0	84	1.0	72	0.9	61	0.7	69	0.8
Washington	35	0.5	34	0.5	33	0.5	44	0.6	34	0.5
West Virginia	113	6.1	141	7.6	195	10.5	186	10.1	272	14.7
Wisconsin	17	0.3	22	0.4	9	0.2	11	0.2	5	0.1
Wyoming	0	0.0	0	0.0	U	U	U	U	U	U
Total	2903	0.9	2895	0.9	3050	1.0	2791	0.9	3370	1.1

Source: CDC, National Notifiable Diseases Surveillance System.
*Rate per 100,000 population.
U=No data available for reporting.

Table 3.2. Select Clinical Characteristics of Acute Hepatitis B Cases* Reported in the United States, 2015

Clinical characteristic	Availability of valid data† for clinical characteristic		Cases with clinical characteristic§
Clinical characteristic	No.	%	No.	%
Jaundice	2,526	75.0	1,891	74.9
Hospitalized for hepatitis B	2,515	74.6	1,502	59.7
Died from hepatitis B	2,311	68.6	20	0.9

Source: CDC, National Notifiable Diseases Surveillance System.
*A total of 3,370 hepatitis B cases were reported during 2015.
†Case reports for which questions regarding clinical characteristics were answered with “yes” or “no.” Reports with any other response were excluded.
§Numbers and percentages represent only those case reports for which data regarding clinical characteristics were available; numbers likely are underestimates.

Table 3.3. Number of newly reported case* reports^_† of confirmed chronic hepatitis B submitted by states or jurisdictions, 2015

State/Jurisdiction	No. chronic hepatitis B case reports submitted^†
Alabama	N
Alaska	N
Arizona	133
Arkansas	N
California	1,008
Colorado	163
Connecticut	38
Delaware	122
District of Columbia	U
Florida	1,423
Georgia	1,867
Hawaii	N
Idaho	51
Illinois	440
Indiana	68
Iowa	39
Kansas	130
Kentucky	16
Louisiana	201
Maine	51
Maryland	566
Massachusetts	284
Michigan	350
Minnesota	186
Mississippi	N
Missouri	521
Montana	31
Nebraska	93
Nevada	N
New Hampshire	N
New Jersey	273
New Mexico	41
New York	2,315
North Carolina	507
North Dakota	53
Ohio	890
Oklahoma	84
Oregon	138
Pennsylvania	857
Rhode Island	U
South Carolina	156
South Dakota	23
Tennessee	253
Texas	N
Utah	64
Vermont	39
Virginia	556
Washington	119
West Virginia	225
Wisconsin	N
Wyoming	42
Total	14,416

Source: CDC, National Notifiable Diseases Surveillance System.
*For case-definition, see https://wwwn.cdc.gov/nndss/conditions/hepatitis-b-chronic/case-definition/2012/
^†Reports may not reflect unique cases.
^§ Cases reported by California through NNDSS were all from San Francisco County. The number of cases in this table and table 3.4 differ because NNDSS and CDC’s Secure Access Management System (SAMS)
N= Not Reportable, chronic hepatitis B infection is not reportable in the listed state.
U=No data available for reporting

Table 3.4. Reported cases of chronic hepatitis B, by demographic characteristics and laboratory tests — Enhanced Viral Hepatitis Surveillance Sites, 2015

Category	FL* No. %	MA No. %	MI No. %	NYS† No. %	Phil No. %	SF No. %	WA No. %	Total No. %
Sex
Female	641	222	167	334	47	501	67	1979
Female	44.5%	47.0%	46.4%	43.1%	39.5%	47.0%	44.1%	45.1%
Male	798	250	193	440	71	566	83	2401
Male	55.4%	53.0%	53.6%	56.8%	59.7%	53.0%	54.6%	54.7%
Unknown /missing	2	0	0	1	1	0	2	6
Unknown /missing	0.10%	0.00%	0.00%	0.10%	0.80%	0.00%	1.30%	0.10%
Race/Ethnicity
American Indian/ Alaska Native, NH¶	0	8	6	1	1	0	0	16
American Indian/ Alaska Native, NH¶	0.0%	1.7%	1.7%	0.1%	0.8%	0.0%	0.0%	0.4%
Asian/Pacific Islander, NH	81	159	90	265	45	562	22	1224
Asian/Pacific Islander, NH	5.6%	33.7%	25.0%	34.2%	37.8%	52.7%	14.5%	27.9%
Black, NH	187	87	46	92	23	13	12	460
Black, NH	13.0%	18.4%	12.8%	11.9%	19.3%	1.2%	7.9%	10.5%
White, NH	290	48	108	86	12	26	13	583
White, NH	20.1%	10.2%	30.0%	11.1%	10.1%	2.4%	8.6%	13.3%
Hispanic	90	15	5	40	5	20	4	179
Hispanic	6.2%	3.2%	1.4%	5.2%	4.2%	1.9%	2.6%	4.1%
Other, NH	47	28	22	33	4	10	5	149
Other, NH	3.3%	5.9%	6.1%	4.3%	3.4%	0.9%	4.2%	3.4%
Unknown /missing	746	135	83	258	29	436	96	1783
Unknown /missing	51.8%	28.6%	23.1%	33.3%	24.4%	40.9%	63.2%	40.7%
Age group, years
0-14	9	6	8	4	1	7	3	38
0-14	0.6%	1.3%	2.2%	0.5%	0.8%	0.7%	2.0%	0.9%
15-24	67	33	26	63	9	43	15	256
15-24	4.6%	7.0%	7.2%	8.1%	7.6%	4.0%	9.9%	5.8%
25-39	428	209	116	292	41	339	52	1,477
25-39	29.7%	44.3%	32.2%	37.7%	34.5%	31.8%	34.2%	33.7%
40-54	479	126	114	235	43	378	47	1,422
40-54	33.2%	26.7%	31.7%	30.3%	36.1%	35.4%	30.9%	32.4%
55+	458	98	96	181	25	303	35	1,196
55+	31.8%	20.8%	26.7%	23.4%	21.0%	28.4%	23.0%	27.3%
Unknown /missing	0	0	0	0	0	0	0	0
Unknown /missing	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%
Place of Birth
United States	–	25	85	5	51	14	–	180
United States	–	5.3%	23.6%	0.6%	42.9%	1.3%	–	4.1%
Outside United States	–	180	128	24	62	136	–	530
Outside United States	–	38.1%	35.6%	3.1%	52.1%	12.7%	–	12.1%
Unknown /missing	1,441	267	147	746	6	917	152	3,676
Unknown /missing	100.00%	56.6%	40.8%	96.3%	5.0%	85.9%	100.0%	83.8%
Hepatitis B laboratory testing**
HBV surface antigen +	1,301	398	270	690	97	943	90	3,789
HBV surface antigen +	90.3%	84.3%	75.0%	89.0%	81.5%	88.4%	59.2%	86.4%
[IgM anti-HBc] –	986	84	63	236	0	0	0	1,369
[IgM anti-HBc] –	68.4%	17.8%	17.5%	30.5%	0.0%	0.0%	0.0%	31.2%
HBV “e” antigen +	193	85	12	136	35	106	20	587
HBV “e” antigen +	13.4%	18.0%	3.3%	17.5%	29.4%	9.9%	13.2%	13.4%
HBV NAT +	652	382	13	338	99	941	24	2,449
HBV NAT +	45.2%	80.9%	3.6%	43.6%	83.2%	88.2%	15.8%	55.8%
Total no. cases	1,441	472	360	775	119	1,067	152	4,386
2015 Estimated population total††	20,271,272	6,794,422	9,922,576	11,245,386	1,567,442	864,816	7,170,351	57,836,265
Rate per 100,000 population	7.1	6.9	3.6	6.9	7.6	123.4	2.1	7.6

Source: CDC, Enhanced Viral Hepatitis Surveillance Sites.
Abbreviations: FL, Florida, MA, Massachusetts; MI, Michigan; NYS, New York State; Phil, Philadelphia; SF, San Francisco; WA, Washington State
Percentages may not sum to 100% due to rounding.
* Florida DOH only reported cases from the following 10 counties: Alachua, Broward, Hillsborough, Miami-Dade, Orange, Palm Beach, Pinellas, Polk, Sarasota, and Seminole
†New York City was not included in the case count for New York State, therefore cases and population estimates from New York excluded those who resided in New York City
§The denominator used to calculate proportions was the total number of cases reported for each site.
¶NH: Non-Hispanic
**Cases can be reported with more than one laboratory test result.
††Population estimates for the United States: https://www.census.gov/quickfacts/table/PST045216/00
HBV: Hepatitis B Virus; IgM anti-HBc (Anti-Hepatitis B core IgM); NAT: HBV nucleic acid testing.

Table 3.5. Number and rate* of hepatitis B-related deaths^†, by demographic characteristics and year – United States, 2011-2015

Demographic characteristic		2011		2012		2013		2014		2015
Demographic characteristic		No.	Rate	No.	Rate	No.	Rate	No.	Rate	No.	Rate
Age Group (years)^§	0–34	41	0.03	38	0.03	40	0.03	35	0.02	31	0.02
	35–44	143	0.35	123	0.30	146	0.36	126	0.31	120	.3
	45–54	421	0.94	428	0.97	389	0.89	384	0.88	332	0.77
	55–64	645	1.69	639	1.66	704	1.79	684	1.71	611	1.49
	65–74	285	1.27	314	1.31	343	1.36	358	1.36	384	1.39
	≥75	269	1.42	229	1.20	251	1.29	256	1.29	236	1.17
Race / ethnicity^¶	White NH (non-Hispanic)	832	0.32	818	0.31	868	0.33	853	0.32	809	0.3
	Black NH	373	0.98	322	0.81	384	0.98	330	0.80	320	0.78
	Hispanic	161	0.48	139	0.39	149	0.39	155	0.38	134	0.32
	Asian / Pacific Islander	422	2.72	469	2.93	451	2.64	478	2.71	420	2.24
	American Indian / Alaska Native	9	0.39	18	0.74	14	0.55	11	0.43	16	0.58
Sex	Male	1,321	0.80	1,272	0.75	1,375	0.79	1,307	0.74	1277	0.72
Sex	Female	483	0.26	499	0.27	498	0.26	536	0.27	438	0.22
Overall		1,804	0.52	1,771	0.50	1,873	0.52	1,843	0.50	1,715	0.45

Source: CDC, National Vital Statistics System.
*Rates for race, sex, and overall total are age-adjusted per 100,000 U.S. standard population in 2000.
†Cause of death is defined as the underlying cause of death or one of the multiple causes of death and is based on the International Classification of Diseases, 10th Revision (ICD-10) codes B16, B17.0, B18.0, B18.1 (hepatitis B).
§ One death in 2015 is not represented under the age group category due to missing data
¶ Seven deaths in 2011, five deaths in 2012, seven deaths in 2013, 16 deaths in 2014, and 16 deaths in 2015 are not represented under the race/ethnicity category due to missing data.

Table 3.6. Number of newly reported case* reports^† of perinatal hepatitis B§ submitted by states and jurisdictions, 2015

State/Jurisdiction	No. Perinatal hepatitis B case reports† submitted
Alabama	1
California	11
Colorado	1
Connecticut	1
Georgia	2
Hawaii	1
Massachusetts	1
Minnesota	3
Nebraska	1
Nevada	1
New York	4
North Carolina	1
Oregon	2
Texas	1
Virginia	1
Washington	1
West Virginia	2
Wisconsin	2
Total	37

Source: CDC, National Notifiable Diseases Surveillance System.
*For case-definition, see https://wwwn.cdc.gov/nndss/conditions/hepatitis-b-perinatal-virus-infection/case-definition/1995/
†Reports may not reflect unique cases.
^§ Perinatal hepatitis B is not reportable disease in ALL jurisdictions

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Hepatitis C virus

Index-HepC

PAGE	DESCRIPTION
Table 4.1	Reported cases of acute hepatitis C, nationally and by state and jurisdiction ―United States, 2011-2015
Table 4.2	Select Clinical Characteristics of Acute Hepatitis C Cases Reported in the United States, 2015
Table 4.3	Number of newly reported case reports of confirmed past or present Hepatitis C submitted by states and jurisdictions, 2015
Table 4.4	Reported cases of past or present hepatitis C, by demographic characteristics and laboratory tests — Enhanced Viral Hepatitis Surveillance Sites, 2015
Table 4.5	Number and rate of hepatitis C-related deaths†, by demographic characteristic and year — United States, 2011-2015
Figure 4.1	Reported number of acute hepatitis C — United States, 2000–2015
Figure 4.2	Incidence of acute hepatitis C, by age group — United States, 2000–2015
Figure 4.3	Incidence of acute hepatitis C, by sex — United States, 2000–2015
Figure 4.4	Incidence of acute hepatitis C, by race/ethnicity — United States, 2000–2015
Figure 4.5	Availability of information on risk exposures/behaviors associated with acute hepatitis C — United States, 2015
Figure 4.6a	Acute hepatitis C reports, by risk exposure/behavior — United States, 2015
Figure 4.6b	Acute hepatitis C reports, by risk exposure/behavior — United States, 2015
Map 4.1	2015 State Acute Hepatitis C Incidence Compared to Healthy People 2020 National Goal

Hepatitis C virus

Table 4.1. Reported cases of acute hepatitis C, nationally and by state and jurisdiction ―United States, 2011-2015

State	2011		2012		2013		2014		2015
State	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*
Alabama	23	0.5	24	0.5	30	0.6	35	0.7	70	1.4
Alaska	U	U	U	U	U	U	U	U	U	U
Arizona	U	U	U	U	U	U	U	U	U	U
Arkansas	0	0.0	5	0.2	30	1.0	13	0.4	2	0.1
California	48	0.1	63	0.2	72	0.2	73	0.2	59	0.2
Colorado	28	0.5	42	0.8	21	0.4	33	0.6	40	0.7
Connecticut	47	1.3	34	0.9	U	U	U	U	U	U
Delaware	3	0.3	U	U	U	U	U	U	4	0.4
District of Columbia	U	U	U	U	U	U	U	U	U	U
Florida	64	0.3	107	0.6	134	0.7	93	0.5	126	0.6
Georgia	53	0.5	82	0.8	48	0.5	57	0.6	84	0.8
Hawaii	U	U	U	U	U	U	U	U	U	U
Idaho	12	0.8	11	0.7	14	0.9	6	0.4	4	0.2
Illinois	6	0.0	26	0.2	37	0.3	27	0.2	31	0.2
Indiana	84	1.3	110	1.7	175	2.7	122	1.8	138	2.1
Iowa	0	0.0	3	0.1	U	U	U	U	U	U
Kansas	8	0.3	16	0.6	17	0.6	28	1.0	22	0.8
Kentucky	142	3.2	178	4.1	226	5.1	176	4.0	119	2.7
Louisiana	7	0.2	11	0.2	19	0.4	22	0.5	24	0.5
Maine	12	0.9	8	0.6	8	0.6	31	2.3	30	2.3
Maryland	35	0.6	39	0.7	53	0.9	42	0.7	38	0.6
Massachusetts	23	0.3	37	0.6	174	2.6	228	3.4	249	3.7
Michigan	32	0.3	76	0.8	74	0.7	78	0.8	83	0.8
Minnesota	17	0.3	32	0.6	47	0.9	40	0.7	37	0.7
Mississippi	U	U	U	U	U	U	U	U	U	U
Missouri	8	0.1	4	0.1	6	0.1	6	0.1	8	0.1
Montana	9	0.9	9	0.9	16	1.6	13	1.3	15	1.5
Nebraska	2	0.1	3	0.2	2	0.1	2	0.1	8	0.4
Nevada	10	0.4	12	0.4	9	0.3	6	0.2	12	0.4
New Hampshire	U	U	U	U	U	U	U	U	U	U
New Jersey	53	0.6	71	0.8	106	1.2	113	1.3	130	1.5
New Mexico	14	0.7	21	1.0	12	0.6	16	0.8	40	1.9
New York	52	0.3	93	0.5	131	0.7	126	0.6	121	0.6
North Carolina	60	0.6	63	0.6	79	0.8	111	1.1	144	1.4
North Dakota	0	0.0	0	0.0	4	0.6	0	0.0	0	0.0
Ohio	6	0.1	7	0.1	116	1.0	105	0.9	122	1.1
Oklahoma	53	1.4	80	2.1	40	1.0	45	1.2	35	0.9
Oregon	20	0.5	37	0.9	14	0.4	15	0.4	13	0.3
Pennsylvania	35	0.3	66	0.5	81	0.6	69	0.5	129	1.0
Rhode Island	U	U	U	U	U	U	U	U	U	U
South Carolina	1	0.0	1	0.0	0	0.0	4	0.1	5	0.1
South Dakota	U	U	U	U	U	U	U	U	U	U
Tennessee	83	1.3	129	2.0	98	1.5	123	1.9	173	2.6
Texas	37	0.1	44	0.2	28	0.1	47	0.2	48	0.2
Utah	10	0.4	17	0.6	11	0.4	38	1.3	30	1.0
Vermont	6	1.0	6	1.0	3	0.5	4	0.6	1	0.2
Virginia	25	0.3	76	0.9	41	0.5	54	0.6	52	0.6
Washington	41	0.6	54	0.8	63	0.9	82	1.2	63	0.9
West Virginia	46	2.5	55	3.0	58	3.1	62	3.4	63	3.4
Wisconsin	15	0.3	26	0.5	40	0.7	49	0.9	64	1.1
Wyoming	2	0.4	U	U	U	U	U	U	U	U
Total	1232	0.4	1778	0.6	2138	0.7	2194	0.7	2436	0.8

Source: CDC, National Notifiable Diseases Surveillance System.
*Rate per 100,000 population.
U=No data available for reporting.

Table 4.2. Select Clinical Characteristics of Acute Hepatitis C Cases* Reported in the United States, 2015

Clinical characteristic	Availability of valid data† for clinical characteristic		Cases with clinical characteristic§
Clinical characteristic	No.	%	No.	%
Jaundice	1,696	69.6	927	54.7
Hospitalized for hepatitis C	1,552	63.7	822	53.0
Died from hepatitis C	1,318	54.1	6	0.5

Source: CDC, National Notifiable Diseases Surveillance System.
*A total of 2,436 acute hepatitis C cases were reported during 2015.
^†Case reports for which questions regarding clinical characteristics were answered with “yes” or “no.” Reports with any other response were excluded.
^§Numbers and percentages represent only those case reports for which data regarding clinical characteristics were available; numbers likely are underestimates.

Table 4.3. Number of newly reported case* reports^† of confirmed past or present Hepatitis C submitted by states and jurisdictions, 2015

State/Jurisdiction	No. past/present hepatitis C case reports submitted^†
Alabama	N
Alaska	1,604
Arizona	U
Arkansas	1
California^§	1,182
Colorado	3,561
Connecticut	3,291
Delaware	31
District of Columbia	U
Florida	22,793
Georgia	7,175
Hawaii	U
Idaho	1,017
Illinois	8,696
Indiana	U
Iowa	20
Kansas	1,697
Kentucky	4
Louisiana	2,478
Maine	1,486
Maryland	7,425
Massachusetts	5,482
Michigan	6,808
Minnesota	2,015
Mississippi	N
Missouri	7,800
Montana	1,354
Nebraska	893
Nevada	N
New Hampshire	N
New Jersey	7,928
New Mexico	3,680
New York	15,058
North Carolina	N
North Dakota	794
Ohio	19,165
Oklahoma	590
Oregon	5,472
Pennsylvania	11,988
Rhode Island	U
South Carolina	4,515
South Dakota	567
Tennessee	2,251
Texas	N
Utah	1,578
Vermont	808
Virginia	8,138
Washington	5,712
West Virginia	6,339
Wisconsin	3
Wyoming	472
Total	181,871

Source: CDC, National Notifiable Diseases Surveillance System
*For case-definition, see https://wwwn.cdc.gov/nndss/conditions/hepatitis-c-chronic/case-definition/2012/.
^†Reports may not reflect unique cases.
^§Cases reported by California through NNDSS were all from San Francisco County. Differences in the number of cases in this table and table 4.4 are because NNDSS and CDC’s Secure Access Management System (SAMS) have different data close-out dates by which all annual data must be submitted.
N=Not Reportable, past/present hepatitis C is not reportable in the listed state.
U= No data available for reporting

Table 4.4. Reported cases of past or present hepatitis C, by demographic characteristics and laboratory tests – Enhanced Viral Hepatitis Surveillance Sites, 2015

Category	FL* No. %^§	MA No. %	MI No. %	NYS^† No. %	Phil No. %	SF No. %	WA No. %	Total No. %
Sex
Female	10,271	2,334	2,666	3,151	560	431	2,236	21,649
Female	40.2%	39.9%	37.9%	37.7%	33.5%	27.2%	37.6%	38.6%
Male	15,206	3,500	4,352	5,131	1,097	1,152	3,639	34,077
Male	59.5%	59.8%	61.9%	61.4%	65.7%	72.7%	61.1%	60.8%
Unknown /missing	98	21	14	71	14	2	80	303
Unknown /missing	0.4%	0.4%	0.2%	0.8%	0.8%	0.1%	1.3%	0.5%
Race/ethnicity
American Indian/ Alaska Native, NH^¶	29	14	58	43	2	5	0	151
American Indian/ Alaska Native, NH^¶	0.1%	0.2%	0.8%	0.5%	0.1%	0.3%	0.0%	0.3%
Asian/Pacific Islander, NH	54	97	44	97	13	57	39	404
Asian/Pacific Islander, NH	0.2%	1.7%	0.6%	1.2%	0.8%	3.6%	0.7%	0.7%
Black, NH	957	243	1,184	682	153	234	164	3,617
Black, NH	3.7%	4.2%	16.8%	8.2%	9.2%	14.8%	2.8%	6.5%
White, NH	7,519	2,566	3,346	4,067	185	580	1,611	19,874
White, NH	29.4%	43.8%	47.6%	48.7%	11.1%	36.6%	27.1%	35.5%
Hispanic	1,135	330	112	541	89	116	135	2,458
Hispanic	4.4%	5.6%	1.6%	6.5%	5.3%	7.3%	2.3%	4.4%
Other, NH	271	210	86	132	12	0	42	753
Other, NH	1.1%	3.6%	1.2%	1.6%	0.7%	0.0%	0.7%	1.3%
Unknown /missing	15,610	2,395	2,202	2,791	1,217	593	3,964	28,772
Unknown /missing	61.0%	40.9%	31.3%	33.4%	72.8%	37.4%	66.6%	51.0%
Age group, years
0-14	67	25	16	15	10	1	18	152
0-14	0.3%	0.4%	0.2%	0.2%	0.6%	0.1%	0.3%	0.3%
15-24	2,343	794	537	1,064	58	35	427	5,258
15-24	9.2%	13.6%	7.6%	12.7%	3.5%	2.2%	7.2%	9.4%
25-39	7,071	2,197	1,795	2,720	362	295	1,473	15,913
25-39	27.6%	37.5%	25.5%	32.6%	21.7%	18.6%	24.7%	28.4%
40-54	6,314	1,285	1,454	1,787	466	452	1,590	13,348
40-54	24.7%	21.9%	20.7%	21.4%	27.9%	28.5%	26.7%	23.7%
55+	9,766	1,546	3,226	2,752	773	792	2,438	21,293
55+	38.2%	26.4%	45.9%	32.9%	46.3%	50.0%	40.9%	38.0%
Unknown /missing	14	8	4	15	2	10	9	62
Unknown /missing	0.1%	0.1%	0.1%	0.2%	0.1%	0.6%	0.2%	0.1%
Hepatitis C laboratory testing**
Anti-HCV+	15,975	4,613	4,861	5,715	987	977	3,862	36,990
Anti-HCV+	62.5%	78.8%	69.1%	68.4%	59.1%	61.6%	64.9%	66.0%
HCV RNA+	15,226	4,505	2,318	5,862	1,639	1,179	2,656	33,385
HCV RNA+	59.5%	76.9%	33.0%	70.2%	98.1%	74.4%	44.6%	59.6%
Total no. cases	25,575	5,855	7,032	8,353	1,671	1,585	5,955	56,026
2015 Estimated population total^††	20,271,272	6,794,422	9,922,576	11,245,386	1,567,442	864,816	7,170,351	57,836,265
Rate per 100,000 population	126.2	86.2	70.9	74.3	106.6	183.3	83.1	96.9

Source: CDC, Enhanced Viral Hepatitis Surveillance Sites.
Abbreviations: FL, Florida; MA, Massachusetts; MI, Michigan; NYS, New York State; Phil, Philadelphia; SF, San Francisco; WA, Washington State
*Florida DOH only reported cases from the following 10 counties: Alachua, Broward, Hillsborough, Miami-Dade, Orange, Palm Beach, Pinellas, Polk, Sarasota, and Seminole
^†Cases and population estimates from New York excluded those who resided in New York City because New York City was not included in the reported case counts.
^§The denominator used to calculate proportions was the total number of cases reported for each site.
NH: Non-Hispanic
** Cases can be reported with more than one laboratory test result.
†† Population estimates for the United States: https://www.census.gov/quickfacts/table/PST045216/00 .
HCV: Hepatitis C virus; Anti-HCV: Hepatitis C Antibody: HCV RNA: Ribonucleic acid.

Table 4.5. Number and rate* of hepatitis C-related deaths^†, by demographic characteristic and year — United States, 2011-2015

Demographic characteristic		2011		2012		2013		2014		2015
Demographic characteristic		No.	Rate	No.	Rate	No.	Rate	No.	Rate	No.	Rate
Age Group (years)^§	0–34	128	0.09	158	0.11	121	0.08	162	0.11	196	0.13
	35–44	696	1.71	622	1.54	573	1.42	552	1.36	597	1.47
	45–54	5,073	11.34	4,749	10.73	4,344	9.93	4,118	9.48	3,676	8.51
	55–64	8,330	21.89	9,235	23.93	9,899	25.18	9,999	24.95	9,702	23.73
	65–74	2,136	9.50	2,515	10.49	3,004	11.91	3,390	12.84	4,023	14.60
	>75	1,357	7.18	1,369	7.15	1,425	7.31	1,433	7.22	1,434	7.10
Race/ ethnicity^¶	White, NH (non-Hispanic)	11,196	4.19	11,839	4.35	12,219	4.40	12,455	4.46	12,355	4.38
	Black, NH	3,167	7.89	3,232	7.81	3,520	8.35	3,540	8.12	3,606	8.14
	Hispanic	2,555	7.15	2,668	7.19	2,699	6.91	2,767	6.81	2,699	6.40
	Asian/Pacific Islander	455	3.14	472	3.15	495	3.09	438	2.56	445	2.49
	American Indian/Alaska Native	275	10.61	313	11.81	324	12.22	317	11.2	367	12.95
Sex	Male	12,651	7.11	13,300	7.31	13,745	7.40	13,998	7.39	14,095	7.31
Sex	Female	5,070	2.70	5,350	2.77	5,623	2.85	5,661	2.81	5,534	2.71
Overall		17,721	4.82	18,650	4.96	19,368	5.03	19,659	5.01	19,629	4.91

Source: CDC, National Vital Statistics System.
*Rates for race, sex, and overall total are age-adjusted per 100,000 U.S. standard population in 2000.
^†Cause of death is defined as the underlying cause of death or one of the multiple causes of death and is based on the International Classification of Diseases, 10th Revision (ICD-10) codes B17.1, and B18.2 (hepatitis C).
^§One death in 2011, two deaths in 2012, two deaths in 2013, five deaths in 2014, and one death in 2015 are not represented under the age category due to missing age data.
^¶The race/ethnicity category was added starting in 2010 to incorporate bridged race categories. 73 deaths in 2011, 126 deaths in 2012, 111 deaths in 2013, 142 deaths in 2014, and 157 in 2015 are not represented under the race/ethnicity category due to missing data.

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Viral Hepatitis

Surveillance for Viral Hepatitis – United States, 2015

Contents

Investigation of Healthcare-associated Outbreak Cases

Hepatitis A virus

Index-HepA

Hepatitis A virus

Table 2.1. Reported cases of hepatitis A, nationally and by state or jurisdiction ― United States, 2011–2015

Table 2.2. Select Clinical Characteristics of Hepatitis A Cases* Reported in the United States, 2015

Table 2.3. Number and rate* of hepatitis A-related deaths^†, by demographic characteristics and year — United States, 2011–2015

Hepatitis B virus

Index-HepB

Hepatitis B virus

Table 3.1. Reported cases of acute hepatitis B, nationally and by state or jurisdiction ― United States, 2011–2015

Table 3.2. Select Clinical Characteristics of Acute Hepatitis B Cases* Reported in the United States, 2015

Table 3.3. Number of newly reported case* reports^_† of confirmed chronic hepatitis B submitted by states or jurisdictions, 2015

Table 3.4. Reported cases of chronic hepatitis B, by demographic characteristics and laboratory tests — Enhanced Viral Hepatitis Surveillance Sites, 2015

Table 3.5. Number and rate* of hepatitis B-related deaths^†, by demographic characteristics and year – United States, 2011-2015

Table 3.6. Number of newly reported case* reports^† of perinatal hepatitis B§ submitted by states and jurisdictions, 2015

Hepatitis C virus

Index-HepC

Hepatitis C virus

Table 4.1. Reported cases of acute hepatitis C, nationally and by state and jurisdiction ―United States, 2011-2015

Table 4.2. Select Clinical Characteristics of Acute Hepatitis C Cases* Reported in the United States, 2015

Table 4.3. Number of newly reported case* reports^† of confirmed past or present Hepatitis C submitted by states and jurisdictions, 2015

Table 4.4. Reported cases of past or present hepatitis C, by demographic characteristics and laboratory tests – Enhanced Viral Hepatitis Surveillance Sites, 2015

Table 4.5. Number and rate* of hepatitis C-related deaths^†, by demographic characteristic and year — United States, 2011-2015

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Quick Links to Hepatitis …

Viral Hepatitis Home

Surveillance for Viral Hepatitis – United States, 2015

Contents

Investigation of Healthcare-associated Outbreak Cases

Hepatitis A virus

Index-HepA

Hepatitis A virus

Table 2.1. Reported cases of hepatitis A, nationally and by state or jurisdiction ― United States, 2011–2015

Hepatitis B virus

Index-HepB

Hepatitis B virus

Table 3.1. Reported cases of acute hepatitis B, nationally and by state or jurisdiction ― United States, 2011–2015

Hepatitis C virus

Index-HepC

Hepatitis C virus

Table 4.1. Reported cases of acute hepatitis C, nationally and by state and jurisdiction ―United States, 2011-2015

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Viral Hepatitis Home

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