Surveillance for Viral Hepatitis – United States, 2014

Entire report in a printable format (revised Sep 2016)[PDF – 2MB – 65 pages]

Hepatitis A virus

Index

PAGE	DESCRIPTION
Table 2.1	Reported cases of hepatitis A, nationally and by state or jurisdiction ― United States, 2010-2014
Table 2.2	Clinical characteristics of reported cases of hepatitis A ― United States, 2014
Table 2.3	Number and rate of hepatitis A-related deaths, by demographic characteristics and year — United States, 2010–2014
Figure 2.1	Reported number of acute hepatitis A cases — United States, 2000-2014
Figure 2.2	Incidence of hepatitis A, by age group — United States, 2000-2014
Figure 2.3	Incidence of hepatitis A, by sex — United States, 2000-2014
Figure 2.4	Incidence of hepatitis A, by race/ethnicity — United States, 2000-2014
Figure 2.5	Availability of information on risk exposures/behaviors associated with hepatitis A – United States, 2014
Figure 2.6a	Hepatitis A reports, by risk behavior — United States, 2014
Figure 2.6b	Hepatitis A reports, by risk exposure — United States, 2014

Hepatitis A virus

Table 2.1 Reported cases of hepatitis A, nationally and by state or jurisdiction ― United States, 2010–2014

State	2010		2011		2012		2013		2014
State	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*
Alabama	8	0.2	8	0.2	19	0.4	10	0.2	15	0.3
Alaska	5	0.7	4	0.6	1	0.1	1	0.1	1	0.1
Arizona	61	1.0	77	1.2	93	1.4	66	1.0	29	0.4
Arkansas	2	0.1	3	0.1	8	0.3	9	0.3	2	0.1
California	242	0.6	186	0.5	209	0.5	255	0.7	142	0.4
Colorado	36	0.7	21	0.4	28	0.5	51	1.0	23	0.4
Connecticut	29	0.8	18	0.5	23	0.6	19	0.5	23	0.6
Delaware	7	0.8	2	0.2	9	1.0	4	0.4	1	0.1
District of Columbia	1	0.2	U	U	U	U	U	U	U	U
Florida	139	0.7	87	0.5	87	0.5	115	0.6	90	0.5
Georgia	40	0.4	27	0.3	46	0.5	36	0.4	24	0.2
Hawaii	8	0.6	8	0.6	5	0.4	16	1.1	5	0.4
Idaho	8	0.5	6	0.4	11	0.7	8	0.5	7	0.4
Illinois	48	0.4	73	0.6	67	0.5	79	0.6	82	0.6
Indiana	12	0.2	24	0.4	11	0.2	32	0.5	20	0.3
Iowa	11	0.4	8	0.3	7	0.2	17	0.6	12	0.4
Kansas	14	0.5	4	0.1	15	0.5	11	0.4	7	0.2
Kentucky	26	0.6	10	0.2	25	0.6	24	0.5	19	0.4
Louisiana	11	0.2	5	0.1	7	0.2	14	0.3	5	0.1
Maine	7	0.5	6	0.5	9	0.7	10	0.8	8	0.6
Maryland	23	0.4	26	0.4	28	0.5	29	0.5	27	0.5
Massachusetts	48	0.7	39	0.6	40	0.6	43	0.6	43	0.6
Michigan	73	0.7	70	0.7	100	1.0	83	0.8	45	0.5
Minnesota	37	0.7	27	0.5	29	0.5	32	0.6	19	0.3
Mississippi	2	0.1	7	0.2	11	0.4	5	0.2	3	0.1
Missouri	21	0.4	13	0.2	20	0.3	8	0.1	20	0.3
Montana	4	0.4	3	0.3	6	0.6	6	0.6	5	0.5
Nebraska	14	0.8	5	0.3	16	0.9	13	0.7	9	0.5
Nevada	14	0.5	5	0.2	10	0.4	19	0.7	5	0.2
New Hampshire	2	0.2	0	0	6	0.5	9	0.7	5	0.4
New Jersey	76	0.9	79	0.9	60	0.7	68	0.8	59	0.7
New Mexico	5	0.2	7	0.3	10	0.5	20	1.0	8	0.4
New York	147	0.8	113	0.6	111	0.6	167	0.8	84	0.4
North Carolina	48	0.5	31	0.3	34	0.3	46	0.5	38	0.4
North Dakota	4	0.6	0	0	2	0.3	9	1.2	9	1.2
Ohio	47	0.4	39	0.3	36	0.3	59	0.5	32	0.3
Oklahoma	6	0.2	11	0.3	12	0.3	14	0.4	17	0.4
Oregon	17	0.4	11	0.3	9	0.2	29	0.7	13	0.3
Pennsylvania	53	0.4	60	0.5	62	0.5	53	0.4	48	0.4
Rhode Island	9	0.9	8	0.8	3	0.3	4	0.4	8	0.8
South Carolina	26	0.6	11	0.2	6	0.1	14	0.3	6	0.1
South Dakota	1	0.1	2	0.2	0	0	4	0.5	3	0.4
Tennessee	12	0.2	23	0.4	23	0.4	20	0.3	12	0.2
Texas	139	0.6	138	0.5	134	0.5	109	0.4	124	0.5
Utah	12	0.4	8	0.3	4	0.1	12	0.4	8	0.3
Vermont	0	0	6	1.0	2	0.3	7	1.1	1	0.2
Virginia	52	0.6	30	0.4	49	0.6	36	0.4	27	0.3
Washington	21	0.3	31	0.5	29	0.4	45	0.6	26	0.4
West Virginia	15	0.8	8	0.4	8	0.4	4	0.2	12	0.6
Wisconsin	23	0.4	8	0.1	21	0.4	37	0.6	7	0.1
Wyoming	4	0.7	2	0.4	1	0.2	0	0	1	0.2
U.S.	1670	0.5	1398	0.4	1562	0.5	1781	0.6	1239	0.4

*Rate per 100,000 population.
U=No data available for reporting.
Source: CDC, National Notifiable Diseases Surveillance System.

Table 2.2 Clinical characteristics of reported cases of hepatitis A* ― United States, 2014

Clinical characteristic	Availability of valid data† for clinical characteristic		Cases with clinical characteristic§
Clinical characteristic	No.	%	No.	%
Jaundice	757	61.1	456	60.2
Hospitalized for hepatitis A	757	61.1	344	45.4
Died from hepatitis A	671	54.2	0	0

*A total of 1,239 hepatitis A cases were reported during 2014.
†Case-reports for which questions regarding clinical characteristics were answered with “yes” or “no.” Reports with any other response were excluded.
§Numbers and percentages represent only those case-reports for which data regarding clinical characteristics were available; numbers likely are underestimates.
Source: CDC, National Notifiable Diseases Surveillance System.

Table 2.3 Number and rate* of hepatitis A-related deaths, by demographic characteristics and year — United States, 2010–2014

Demographic characteristic		2010		2011		2012		2013		2014
Demographic characteristic		No.	Rate	No.	Rate	No.	Rate	No.	Rate	No.	Rate
Age Group (years)	0–34	3	0.00	0	0.00	2	0.00	2	0.00	0	0.00
	35–44	7	0.02	1	0.00	5	0.01	2	0.00	4	0.01
	45–54	25	0.06	11	0.02	12	0.03	13	0.03	7	0.02
	55–64	34	0.09	16	0.04	23	0.06	30	0.08	28	0.07
	65–74	10	0.05	12	0.05	17	0.07	19	0.08	19	0.07
	≥75	16	0.09	29	0.15	18	0.09	14	0.07	18	0.09

Race/ ethnicity^†	White NH (non-Hispanic)	65	0.03	44	0.02	51	0.02	63	0.02	51	0.02
	Black NH^¶	15	0.04	10	0.03	8	0.02	6	0.01	11	0.03
	Hispanic	12	0.03	6	0.02	8	0.02	8	0.02	10	0.02
	Asian/Pacific Islander	2	0.02	8	0.06	7	0.05	3	0.02	2	0.01
	American Indian/Alaska Native	1	0.05	1	0.04	2	0.08	0	0.00	2	0.10

Sex	Male	73	0.05	37	0.02	46	0.03	50	0.03	42	0.02
Sex	Female	22	0.01	32	0.02	31	0.02	30	0.01	34	0.02

Overall		95	0.03	69	0.02	77	0.02	80	0.02	76	0.02

Source: CDC, National Vital Statistics System.
*Rates for race, sex, and overall total are age-adjusted per 100,000 U.S. standard population in 2000. Cause of death is defined as the underlying cause of death or one of the multiple causes of death and is based on the International Classification of Diseases, 10th Revision (ICD-10) codes B15 (hepatitis A).
† The race category “white” Included white, non-Hispanic and white Hispanic. The race category “black” included black, non-Hispanic and black Hispanic. The race category “non-white, non-black” included all other races.
One death in 2012 is not represented under the race/ethnicity category due to missing race and/or ethnicity data.

All seven figure slides in PowerPoint[PPTX – 820 KB]

Hepatitis B virus

Index

PAGE	DESCRIPTION
Table 3.1	Reported cases of acute hepatitis B, nationally and by state or jurisdiction ― United States, 2010-2014
Table 3.2	Clinical characteristics of reported cases of acute hepatitis B ― United States, 2014
Table 3.3	Number of newly reported case-reports of confirmed chronic hepatitis B submitted by states and jurisdictions, 2014
Table 3.4	Reported cases of chronic hepatitis B, by demographic characteristics and laboratory tests – Enhanced Viral Hepatitis Surveillance Sites, 2014
Table 3.5	Number and rate of hepatitis B-related deaths, by demographic characteristics and year – United States, 2010-2014
Figure 3.1	Reported number of acute hepatitis B cases — United States, 2000-2014
Figure 3.2	Incidence of acute hepatitis B, by age group — United States, 2000-2014
Figure 3.3	Incidence of acute hepatitis B, by sex — United States, 2000-2014
Figure 3.4	Incidence of acute hepatitis B, by race/ethnicity — United States, 2000-2014
Figure 3.5	Availability of information on risk behaviors/exposures associated with acute hepatitis B — United States, 2014
Figure 3.6a	Acute hepatitis B reports, by risk behavior — United States, 2014
Figure 3.6b	Acute hepatitis B reports, by risk exposure — United States, 2014

Hepatitis B virus

Table 3.1 Reported cases of acute hepatitis B, nationally and by state or jurisdiction ― United States, 2010-2014

State	2010		2011		2012		2013		2014
State	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*
Alabama	68	1.4	119	2.5	79	1.6	90	1.9	117	2.4
Alaska	5	0.7	3	0.4	1	0.1	1	0.1	3	0.4
Arizona	26	0.4	14	0.2	14	0.2	28	0.4	31	0.5
Arkansas	66	2.3	57	1.9	74	2.5	50	1.7	28	0.9
California	252	0.7	157	0.4	136	0.4	138	0.4	110	0.3
Colorado	46	0.9	23	0.4	24	0.5	24	0.5	29	0.5
Connecticut	22	0.6	19	0.5	15	0.4	8	0.2	9	0.3
Delaware	U	U	13	1.4	11	1.2	14	1.5	8	0.9
District of Columbia	3	0.5	U	U	U	U	U	U	U	U
Florida	297	1.6	213	1.1	247	1.3	323	1.7	313	1.6
Georgia	165	1.7	142	1.4	109	1.1	104	1.0	103	1.0
Hawaii	6	0.4	6	0.4	5	0.4	4	0.3	6	0.4
Idaho	6	0.4	2	0.1	5	0.3	13	0.8	6	0.4
Illinois	135	1.1	85	0.7	86	0.7	94	0.7	58	0.5
Indiana	75	1.2	70	1.1	90	1.4	101	1.5	126	1.9
Iowa	15	0.5	15	0.5	13	0.4	11	0.4	9	0.3
Kansas	11	0.4	15	0.5	9	0.3	11	0.4	11	0.4
Kentucky	136	3.1	151	3.5	180	4.1	214	4.9	164	3.7
Louisiana	55	1.2	62	1.4	44	1.0	82	1.8	87	1.9
Maine	13	1.0	8	0.6	9	0.7	11	0.8	12	0.9
Maryland	67	1.2	62	1.1	52	0.9	43	0.7	40	0.7
Massachusetts	13	0.2	67	1.0	75	1.1	71	1.1	30	0.4
Michigan	122	1.2	91	0.9	81	0.8	53	0.5	50	0.5
Minnesota	23	0.4	20	0.4	17	0.3	19	0.4	16	0.3
Mississippi	33	1.1	57	1.9	78	2.6	55	1.8	48	1.6
Missouri	67	1.1	60	1.0	48	0.8	61	1.0	31	0.5
Montana	0	0.0	0	0.0	2	0.2	4	0.4	0	0.0
Nebraska	12	0.7	12	0.7	10	0.5	9	0.5	8	0.4
Nevada	41	1.5	29	1.1	28	1.0	29	1.0	21	0.7
New Hampshire	5	0.4	3	0.2	4	0.3	2	0.2	4	0.3
New Jersey	77	0.9	73	0.8	70	0.8	65	0.7	77	0.9
New Mexico	5	0.2	10	0.5	3	0.1	3	0.1	2	0.1
New York	139	0.7	134	0.7	113	0.6	117	0.6	95	0.5
North Carolina	113	1.2	109	1.1	73	0.7	75	0.8	100	1.0
North Dakota	0	0.0	0	0.0	0	0.0	0	0.0	0	0.0
Ohio	95	0.8	90	0.8	178	1.5	225	1.9	171	1.5
Oklahoma	115	3.1	100	2.6	79	2.1	40	1.0	57	1.5
Oregon	42	1.1	32	0.8	25	0.6	32	0.8	32	0.8
Pennsylvania	72	0.6	84	0.7	63	0.5	43	0.3	68	0.5
Rhode Island	U	U	U	U	U	U	U	U	U	U
South Carolina	59	1.3	39	0.8	37	0.8	58	1.2	37	0.8
South Dakota	2	0.2	2	0.2	2	0.2	5	0.6	3	0.4
Tennessee	150	2.4	192	3.0	240	3.7	262	4.0	232	3.5
Texas	394	1.6	204	0.8	170	0.7	142	0.5	122	0.5
Utah	8	0.3	10	0.4	13	0.5	5	0.2	11	0.4
Vermont	2	0.3	0	0.0	2	0.3	2	0.3	4	0.6
Virginia	97	1.2	84	1.0	84	1.0	72	0.9	61	0.7
Washington	50	0.7	35	0.5	34	0.5	33	0.5	44	0.6
West Virginia	88	4.7	113	6.1	141	7.6	195	10.5	186	10.1
Wisconsin	54	0.9	17	0.3	22	0.4	9	0.2	11	0.2
Wyoming	3	0.5	0	0.0	0	0.0	U	U	U	U
Total	3350	1.1	2903	0.9	2895	0.9	3050	1.0	2791	0.9

Source: CDC, National Notifiable Diseases Surveillance System.
*Rate per 100,000 population.
^†Updated data for Delaware in 2011.
U=No data available for reporting.

Table 3.2 Clinical characteristics of reported cases of acute hepatitis B* ― United States, 2014

Clinical characteristic^†	Availability of valid data† for clinical characteristic		Cases with clinical characteristic§
Clinical characteristic^†	No.	%	No.	%
Jaundice	2,021	72.4	1,544	76.4
Hospitalized for hepatitis B	2,014	72.2	1,240	61.6
Died from hepatitis B	1,806	64.7	13	0.7

Source: CDC, National Notifiable Diseases Surveillance System.
*A total of 2,791 hepatitis B cases were reported during 2014.
^†Case-reports for which questions regarding clinical characteristics were answered with “yes” or “no.” Reports with any other response were excluded.
^§Numbers and percentages represent only those case-reports for which data regarding clinical characteristics were available; numbers likely are underestimates.

Table 3.3 Number of newly reported case-reports* of confirmed chronic hepatitis B submitted by states and jurisdictions, 2014

State/Jurisdiction	No. chronic hepatitis B case reports submitted^†
Alabama	N^§
Alaska	N
Arizona	98
Arkansas	N
California	1,114
Colorado	144
Connecticut	72
Delaware	88
District of Columbia	U^¶
Florida	1,137
Georgia	N
Hawaii	182
Idaho	51
Illinois	972
Indiana	U
Iowa	66
Kansas	116
Kentucky	N
Louisiana	125
Maine	44
Maryland	498
Massachusetts	233
Michigan	475
Minnesota	197
Mississippi	N
Missouri	431
Montana	26
Nebraska	110
Nevada	N
New Hampshire	28
New Jersey	487
New Mexico	50
New York State	2,255
North Carolina	447
North Dakota	83
Ohio	214
Oklahoma	86
Oregon	97
Pennsylvania	927
Rhode Island	U
South Carolina	145
South Dakota	10
Tennessee	625
Texas	N
Utah	34
Vermont	34
Virginia	341
Washington	93
West Virginia	218
Wisconsin	1
Wyoming	46
Total	12,400

Source: CDC, National Notifiable Diseases Surveillance System.
*For case-definition, see https://wwwn.cdc.gov/nndss/conditions/notifiable/2016/
^†Reports may not reflect unique cases.
^§N= Not Reportable, past/present hepatitis C infection is not reportable in the listed state.
^¶ Cases reported by California through NNDSS were all from San Francisco County. Differences in the number o cases in this table and table 3.4 is because NNSDSS and CDC’s Secure Access Management System (SAMS) have different deadline dated for which all annual data must be submitted.
^**U=No data available for reporting

Table 3.4. Reported cases of chronic hepatitis B, by demographic characteristics and laboratory tests – Enhanced Viral Hepatitis Surveillance Sites*, 2014

Category	MA No. %	MI No. %	NYS† No. %	Phil No. %	SF No. %	WA No. %	Total No. %
Sex
Female	110	240	253	32	588	28	1,251
Female	49.1%	49.5%	42.7%	34.4%	50.5%	31.1%	47.2%
Male	114	245	337	60	575	62	1,393
Male	50.9%	50.5%	56.8%	64.5%	49.4%	68.9%	52.6%
Unknown/ missing	0	0	3	1	2	0	6
Unknown/ missing	0.0%	0.0%	0.5%	1.1%	0.2%	0.0%	0.2%
Race/ethnicity
American Indian/ Alaskan Native, non- Hispanic (NH)	0	3	0	0	4	0	7
American Indian/ Alaskan Native, non- Hispanic (NH)	0.0%	0.6%	0.0%	0.0%	0.3%	0.0%	0.3%
Asian / Pacific Islander, NH	66	139	209	35	603	22	1,074
Asian / Pacific Islander, NH	29.5%	28.7%	35.2%	37.6%	51.8%	24.4%	40.5%
Black, NH	35	75	81	25	20	6	242
Black, NH	15.60%	15.50%	13.70%	26.90%	1.70%	6.70%	9.10%
White, NH	28	149	96	5	20	11	309
White, NH	12.5%	30.7%	16.2%	5.4%	1.7%	12.2%	11.7%
Hispanic	24	9	24	2	19	1	79
Hispanic	10.7%	1.9%	4.1%	2.2%	1.6%	1.1%	3.0%
Other, NH	16	25	21	2	7	2	73
Other, NH	7.1%	5.2%	3.5%	2.2%	0.6%	2.2%	2.8%
Unknown/ missing	55	85	162	24	492	48	866
Unknown/ missing	24.6%	17.5%	27.3%	25.8%	42.2%	53.3%	32.7%
Age group, years
0-14	1	8	4	3	5	0	21
0-14	0.4%	1.6%	0.7%	3.2%	0.4%	0.0%	0.8%
15-24	13	49	38	8	35	9	152
15-24	5.8%	10.1%	6.4%	8.6%	3.0%	10.0%	5.7%
25-39	94	149	205	31	373	29	881
25-39	42.0%	30.7%	34.6%	33.3%	32.0%	32.2%	33.2%
40-54	68	143	195	33	422	31	892
40-54	30.4%	29.5%	32.9%	35.5%	36.2%	34.4%	33.7%
55+	48	136	151	18	329	21	703
55+	21.4%	28.0%	25.5%	19.4%	28.2%	23.3%	26.5%
Unknown/ missing	0	0	0	0	1	0	1
Unknown/ missing	0.0%	0.0%	0.0%	0.0%	0.1%	0.0%	0.0%
Place of birth
United States	19	114	3	42	12	1	191
United States	8.5%	23.5%	0.5%	45.2%	1.0%	1.1%	7.2%
Outside United States	103	168	10	44	113	36	474
Outside United States	46.0%	34.6%	1.7%	47.3%	9.7%	40.0%	17.9%
Unknown/ missing	102	203	580	7	1040	53	1,985
Unknown/ missing	45.5%	41.9%	97.8%	7.5%	89.3%	58.9%	74.9%
Hepatitis B laboratory testing¶
HBV surface antigen +	190	326	524	65	1053	21	2,179
HBV surface antigen +	84.8%	67.2%	88.4%	69.9%	90.4%	23.3%	82.2%
[IgM anti-HBc] –	71	80	111	0	0	44	306
[IgM anti-HBc] –	31.7%	16.5%	18.7%	0.0%	0.0%	48.9%	11.5%
HBV “e” antigen +	70	30	97	15	71	4	287
HBV “e” antigen +	31.3%	6.2%	16.4%	16.1%	6.1%	4.4%	10.8%
HBV NAT +	155	50	268	86	999	17	1,577
HBV NAT +	69.2%	10.3%	45.2%	92.5%	85.8%	18.9%	59.4%
Total no. cases	224	485	593	93	1,165	90	2,650
2013 Estimated population total**	6,745,408	9,909,877	11,255,148	1,560,297	852,469	7,061,530	37,384,729
Rate per 100,000 population	3.3	4.9	5.3	6	136.7	1.3	7.1

Source: CDC, Enhanced Viral Hepatitis Surveillance Sites.
Abbreviations: MA, Massachusetts; MI, Michigan; NYS, New York State; Phil, Philadelphia; SF, San Francisco; WA, Washington State
*Chronic hepatitis B data from Florida, one of the 7 funded sites, were not included in this table.
^†New York City was not included in the case count for New York State, therefore cases and population estimates from New York excluded those who resided in New York City
§The denominator used to calculate proportions was the total number of cases reported for each site.
^¶Cases can be reported with more than one laboratory test result.
^**Population estimates for the United States: https://wonder.cdc.gov/bridged-race-population.html.

Table 3.5. Number and rate* of hepatitis B-related deaths^†, by demographic characteristics and year – United States, 2010-2014

Demographic characteristic		2010		2011		2012		2013		2014
Demographic characteristic		No.	Rate	No.	Rate	No.	Rate	No.	Rate	No.	Rate
Age Group (years)	0–34	48	0.03	41	0.03	38	0.03	40	0.03	35	0.02
	35–44	142	0.35	143	0.35	123	0.30	146	0.36	126	0.31
	45–54	448	1.00	421	0.94	428	0.97	389	0.89	384	0.88
	55–64	610	1.67	645	1.69	639	1.66	704	1.79	684	1.71
	65–74	296	1.36	285	1.27	314	1.31	343	1.36	358	1.36
	≥75	248	1.34	269	1.42	229	1.20	251	1.29	256	1.29

Race / ethnicity^†	White NH (non-Hispanic)	856	0.34	832	0.32	818	0.31	868	0.33	853	0.32
	Black NH^¶	356	0.94	373	0.98	322	0.81	384	0.98	330	0.80
	Hispanic	136	0.43	161	0.48	139	0.39	149	0.39	155	0.38
	Asian / Pacific Islander	421	2.95	422	2.72	469	2.93	451	2.64	478	2.71
	American Indian / Alaska Native	17	0.73	9	0.39	18	0.74	14	0.55	11	0.43

Sex	Male	1,316	0.81	1,321	0.80	1,272	0.75	1,375	0.79	1,307	0.74
Sex	Female	476	0.27	483	0.26	499	0.27	498	0.26	536	0.27

Overall		1,792	0.52	1,804	0.52	1,771	0.50	1,873	0.52	1,843	0.50

*Rates for race, sex, and overall total are age-adjusted per 100,000 U.S. standard population in 2000.
†Cause of death is defined as the underlying cause of death or one of the multiple causes of death and is based on the International Classification of Diseases, 10th Revision (ICD-10) codes B16, B17.0, B18.0, B18.1 (hepatitis B).
§ Six deaths in 2010, seven deaths in 2011, five deaths in 2012, seven deaths in 2013, and 16 deaths in 2014 are not represented under the race/ethnicity category due to missing race and/or ethnicity data.
Source: CDC, National Vital Statistics System.

All seven figure slides in PowerPoint[PPTX – 371 KB]

Hepatitis C virus

Index

PAGE	DESCRIPTION
Table 4.1	Reported cases of acute hepatitis C, nationally and by state and jurisdiction ― United States, 2010-2014
Table 4.2	Clinical characteristics of reported cases of acute hepatitis C ― United States, 2014
Table 4.3	Number of newly reported case-reports of confirmed past or present hepatitis C infection submitted by states, 2014
Table 4.4	Reported cases of past or present hepatitis C, by demographic characteristics and laboratory tests – Enhanced Viral Hepatitis Surveillance Sites, 2014
Table 4.5	Number and rate of hepatitis C-related deaths, by demographic characteristics and year – United States, 2010-2014
Slide 4.1	Reported number of acute hepatitis hepatitis C cases — United States, 2000-2014
Slide 4.2	Incidence of acute hepatitis C, by age group — United States, 2000-2014
Slide 4.3	Incidence of acute hepatitis C, by sex — United States, 2000-2014
Slide 4.4	Incidence of acute hepatitis C, by race/ethnicity — United States, 2000-2014
Slide 4.5	Availability of information on risk exposures/behaviors associated with acute hepatitis C — United States, 2014
Slide 4.6a	Acute hepatitis C reports, by risk behavior — United States, 2014
Slide 4.6b	Acute hepatitis C reports, by risk exposure — United States, 2014

Hepatitis C virus

Table 4.1 Reported cases of acute hepatitis C, nationally and by state state and jurisdiction ― United States, 2010-2014

State	2010		2011		2012		2013		2014
State	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*	No.	Rate*
Alabama	7	0.1	23	0.5	24	0.5	30	0.6	35	0.7
Alaska	U	U	U	U	U	U	U	U	U	U
Arizona	U	U	U	U	U	U	U	U	U	U
Arkansas	1	0	0	0	5	0.2	30	1.0	13	0.4
California	32	0.1	48	0.1	63	0.2	72	0.2	73	0.2
Colorado	20	0.4	28	0.5	42	0.8	21	0.4	33	0.6
Connecticut	37	1.0	47	1.3	34	0.9	U	U	U	U
Delaware	U	U	3	0.3	U	U	U	U	U	U
District of Columbia	2	0.3	U	U	U	U	U	U	U	U
Florida	56	0.3	64	0.3	107	0.6	134	0.7	93	0.5
Georgia	32	0.3	53	0.5	82	0.8	48	0.5	57	0.6
Hawaii	U	U	U	U	U	U	U	U	U	U
Idaho	11	0.7	12	0.8	11	0.7	14	0.9	6	0.4
Illinois	1	0	6	0	26	0.2	37	0.3	27	0.2
Indiana	27	0.4	84	1.3	110	1.7	175	2.7	122	1.8
Iowa	0	0	0	0	3	0.1	U	U	U	U
Kansas	2	0.1	8	0.3	16	0.6	17	0.6	28	1.0
Kentucky	109	2.5	142	3.2	178	4.1	226	5.1	176	4.0
Louisiana	4	0.1	7	0.2	11	0.2	19	0.4	22	0.5
Maine	2	0.2	12	0.9	8	0.6	8	0.6	31	2.3
Maryland	24	0.4	35	0.6	39	0.7	53	0.9	42	0.7
Massachusetts	13	0.2	23	0.3	37	0.6	174	2.6	228	3.4
Michigan	45	0.5	32	0.3	76	0.8	74	0.7	78	0.8
Minnesota	16	0.3	17	0.3	32	0.6	47	0.9	40	0.7
Mississippi	U	U	U	U	U	U	U	U	U	U
Missouri	6	0.1	8	0.1	4	0.1	6	0.1	6	0.1
Montana	4	0.4	9	0.9	9	0.9	16	1.6	13	1.3
Nebraska	2	0.1	2	0.1	3	0.2	2	0.1	2	0.1
Nevada	7	0.3	10	0.4	12	0.4	9	0.3	6	0.2
New Hampshire	U	U	U	U	U	U	U	U	U	U
New Jersey	28	0.3	53	0.6	71	0.8	106	1.2	113	1.3
New Mexico	14	0.7	14	0.7	21	1.0	12	0.6	16	0.8
New York	50	0.3	52	0.3	93	0.5	131	0.7	126	0.6
North Carolina	39	0.4	60	0.6	63	0.6	79	0.8	111	1.1
North Dakota	0	0	0	0	0	0	4	0.6	0	0
Ohio	10	0.1	6	0.1	7	0.1	116	1.0	105	0.9
Oklahoma	41	1.1	53	1.4	80	2.1	40	1.0	45	1.2
Oregon	19	0.5	20	0.5	37	0.9	14	0.4	15	0.4
Pennsylvania	26	0.2	35	0.3	66	0.5	81	0.6	69	0.5
Rhode Island	U	U	U	U	U	U	U	U	U	U
South Carolina	1	0	1	0	1	0	0	0	4	0.1
South Dakota	U	U	U	U	U	U	1	0.1	0	0
Tennessee	46	0.7	83	1.3	129	2	98	1.5	123	1.9
Texas	35	0.1	37	0.1	44	0.2	28	0.1	47	0.2
Utah	10	0.4	10	0.4	17	0.6	11	0.4	38	1.3
Vermont	2	0.3	6	1.0	6	1.0	3	0.5	4	0.6
Virginia	13	0.2	25	0.3	76	0.9	41	0.5	54	0.6
Washington	25	0.4	41	0.6	54	0.8	63	0.9	82	1.2
West Virginia	21	1.1	46	2.5	55	3.0	58	3.1	62	3.4
Wisconsin	10	0.2	15	0.3	26	0.5	40	0.7	49	0.9
Wyoming	0	0	2	0.4	U	U	U	U	U	U
Total	850	0.3	1232	0.4	1778	0.6	2138	0.7	2194	0.7

Source: CDC, National Notifiable Diseases Surveillance System.
*Rate per 100,000 population.
U=No data available for reporting.

Table 4.2 Clinical characteristics of reported cases of acute hepatitis C* ― United States, 2014

Clinical characteristic	Availability of valid data† for clinical characteristic		Cases with clinical characteristic§
Clinical characteristic	No.	%	No.	%
Jaundice	1,527	69.6	917	60.1
Hospitalized for hepatitis C	1,371	62.5	733	53.5
Died from hepatitis C	1,242	56.6	6	0.5

Source: CDC, National Notifiable Diseases Surveillance System.
*A total of 2,194 acute hepatitis C cases were reported during 2014.
^†Case-reports for which questions regarding clinical characteristics were answered with “yes” or “no.” Reports with any other response were excluded.
^§Numbers and percentages represent only those case-reports for which data regarding clinical characteristics were available; numbers likely are underestimates.

Table 4.3 Number of newly reported case-reports* of confirmed past or present hepatitis C infection submitted by states, 2014

State/Jurisdiction	No. past/present hepatitis case-reports submitted^†
Alabama	N^§
Alaska	U^¶
Arizona	U
Arkansas	N
California^**	1,317
Colorado	3,644
Connecticut	3,263
Delaware	U
District of Columbia	U
Florida	22,253
Georgia	4,237
Hawaii	11
Idaho	932
Illinois	8,777
Indiana	U
Iowa	U
Kansas	1,560
Kentucky	N
Louisiana	2,116
Maine	1,423
Maryland	7,041
Massachusetts	5,639
Michigan	7,572
Minnesota	1,899
Mississippi	N
Missouri	6,278
Montana	1,413
Nebraska	926
Nevada	N
New Hampshire	N
New Jersey	7,765
New Mexico	2,316
New York State	15,787
North Carolina	N
North Dakota	848
Ohio	15,755
Oklahoma	541
Oregon	5,002
Pennsylvania	10,395
Rhode Island	U
South Carolina	3,586
South Dakota	522
Tennessee	N
Texas	N
Utah	1,492
Vermont	902
Virginia	5,590
Washington	4,928
West Virginia	6,631
Wisconsin	U
Wyoming	502
Total	162,863

Source: CDC, National Notifiable Diseases Surveillance System
*For case-definition, see http://wwwn.cdc.gov/nndss/script/ConditionList.aspx?Type=0&Yr=2012.
^†Reports may not reflect unique cases.
^§N=Not Reportable, past/present hepatitis C is not reportable in the listed state.
^¶U= No data available for reporting
** Cases reported by California through NNDSS were all from San Francisco County. Differences in the number o cases in this table and table 3.4 is because NNSDSS and CDC’s Secure Access Management System (SAMS) have different deadline dated for which all annual data must be submitted.

Table 4.4. Reported cases of past or present hepatitis C, by demographic characteristics and laboratory tests – Enhanced Viral Hepatitis Surveillance Sites, 2014

Category	FL No. %	MA No. %	MI No. %	NYS† No. %	Phil No. %	SF No. %	WA No. %	Total No. %
Sex
Female	572	2,031	2,748	3,008	488	503	1,945	11,295
Female	54.1%	38.6%	36.5%	40.9%	35.5%	30.1%	39.9%	38.8%
Male	484	3,212	4,769	4,293	849	1158	2,878	17,643
Male	45.8%	61.0%	63.3%	58.3%	61.7%	69.2%	59.0%	60.5%
Unknown/ missing	1	20	16	58	39	12	55	201
Unknown/ missing	0.1%	0.4%	0.2%	0.8%	2.8%	0.7%	1.1%	0.7%
Race/ethnicity
American Indian/ Alaskan Native, non-Hispanic (NH)	2	10	62	32	1	9	0	116
American Indian/ Alaskan Native, non-Hispanic (NH)	0.2%	0.2%	0.8%	0.4%	0.1%	0.5%	0.0%	0.4%
Asian/Pacific Islander, NH	6	67	48	92	13	67	49	342
Asian/Pacific Islander, NH	0.6%	1.3%	0.6%	1.3%	0.9%	4.0%	1.0%	1.2%
Black, NH	65	171	1,457	735	217	274	115	3,034
Black, NH	6.1%	3.2%	19.3%	10.0%	15.8%	16.4%	2.4%	10.4%
White, NH	705	1,953	3,875	3,443	196	549	1,102	11,823
White, NH	66.7%	37.1%	51.4%	46.8%	14.2%	32.8%	22.6%	40.6%
Hispanic	84	254	149	401	76	134	70	1,168
Hispanic	7.9%	4.8%	2.0%	5.4%	5.5%	8.0%	1.4%	4.0%
Other, NH	6	127	103	111	11	21	43	422
Other, NH	0.6%	2.4%	1.4%	1.5%	0.8%	1.3%	0.9%	1.4%
Unknown/ missing	189	2,681	1,839	2,545	862	619	3,499	12,234
Unknown/ missing	17.9%	50.9%	24.4%	34.6%	62.6%	37.0%	71.7%	42.0%
Age group, years
0-14	5	45	26	16	5	0	15	112
0-14	0.5%	0.9%	0.3%	0.2%	0.4%	0.0%	0.3%	0.4%
15-24	246	679	587	776	40	44	367	2,739
15-24	23.3%	12.9%	7.8%	10.5%	2.9%	2.6%	7.5%	9.4%
25-39	450	1,874	1,728	1,824	224	286	981	7,367
25-39	42.6%	35.6%	22.9%	24.8%	16.3%	17.1%	20.1%	25.3%
40-54	157	1,295	1,797	1,756	416	493	1,591	7,505
40-54	14.9%	24.6%	23.9%	23.9%	30.2%	29.5%	32.6%	25.8%
55+	199	1,370	3,395	2,969	691	832	1,924	11,380
55+	18.8%	26.0%	45.1%	40.3%	50.2%	49.7%	39.4%	39.1%
Unknown/ missing	0	0.00%	0	18	0	18	0	36
Unknown/ missing	0.0%	0.0%	0.0%	0.2%	0.0%	1.1%	0.0%	0.1%
Hepatitis C laboratory testing^§
Anti-HCV+	761	3,050	5,308	5,014	644	986	1,271	17,034
Anti-HCV+	72.0%	58.0%	70.5%	68.1%	46.8%	58.9%	26.1%	58.4%
HCV RNA +	535	3,206	2,310	4,865	1,334	1,128	2,952	16,330
HCV RNA +	50.6%	60.9%	30.7%	66.1%	96.9%	67.4%	60.5%	56.0%
Total no. cases	1,057	5,263	7,533	7,359	1,376	1,673	4,878	29,139
2013 Estimated population total**	19,893,297	6,745,408	9,909,877	11,255,148	1,560,297	852,469	5,470,019	55,686,515
Rate per 100,000 population	5.3	78.0	76.0	65.4	88.2	196.3	89.2	52.3

Source: CDC, Enhanced Viral Hepatitis Surveillance Sites.
Abbreviations: MA, Massachusetts; MI, Michigan; NYS, New York State; Phil, Philadelphia; SF, San Francisco; WA, Washington State
*Cases and population estimates from New York excluded those who resided in New York City because New York City was not included in the reported case counts.
†The denominator used to calculate proportions was the total number of cases reported for each site.
^§Cases can be reported with more than one laboratory test result.
¶Population estimates for the United States: https://wonder.cdc.gov/bridged-race-population.html.

Table 4.5. Number and rate* of hepatitis C-related deaths^†, by demographic characteristics and year – United States, 2010-2014

Demographic characteristic		2010		2011		2012		2013		2014
Demographic characteristic		No.	Rate	No.	Rate	No.	Rate	No.	Rate	No.	Rate
Age Group (years)	0–34	117	0.08	128	0.09	158	0.11	121	0.08	162	0.11
	35–44	712	1.73	696	1.71	622	1.54	573	1.42	552	1.36
	45–54	5,171	11.49	5,073	11.34	4,749	10.73	4,344	9.93	4,118	9.48
	55–64	7,431	20.37	8,330	21.89	9,235	23.93	9,899	25.18	9,999	24.95
	65–74	1,901	8.75	2,136	9.50	2,515	10.49	3,004	11.91	1,433	7.22
	≥75	1,293	6.97	1,357	7.18	1,369	7.15	1,425	7.31	1,433	7.22

Race / ethnicity^†	White NH (non-Hispanic)	10,575	4.03	11,196	4.19	11,839	4.35	12,219	4.40	12,455	4.46
	Black NH^¶	2,981	7.72	3,167	7.89	3,232	7.81	3,520	8.35	3,540	8.12
	Hispanic	2,318	6.83	2,555	7.15	2,668	7.19	2,699	6.91	2,767	6.81
	Asian/Pacific Islander	440	3.30	455	3.14	472	3.15	495	3.09	438	2.56
	American Indian/Alaska Native	248	9.90	275	10.61	313	11.81	324	12.22	317	11.20

Sex	Male	11,718	6.81	12,651	7.11	13,300	7.31	13,745	7.40	13,998	7.39
Sex	Female	4,846	2.63	5,080	2.70	5,350	2.77	5,623	2.85	5,661	2.81

Overall		16,627	4.56	17,721	4.82	18,650	4.96	19,368	5.03	19,659	5.01

Source: CDC, National Vital Statistics System.
*Rates for race, sex, and overall total are age-adjusted per 100,000 U.S. standard population in 2000.
^†Cause of death is defined as the underlying cause of death or one of the multiple causes of death and is based on the International Classification of Diseases, 10th Revision (ICD-10) codes B17.1, and B18.2 (hepatitis C).
^§Two deaths in 2010, one death in 2011, two deaths in 2012, two deaths in 2013, and five deaths in 2014 are not represented under the age category due to missing age data.
^¶The race/ethnicity category was added starting in 2010 to incorporate bridged race categories. 65 deaths in 2010, 73 deaths in 2011, 126 deaths in 2012, 111 deaths in 2013, and 142 deaths in 2014 are not represented under the race/ethnicity category due to missing race and/or ethnicity data.

All seven figure slides in PowerPoint[PPTX – 369 KB]

* Originally posted 5/4/16, corrected version posted 5/16/16

Viral Hepatitis

Surveillance for Viral Hepatitis – United States, 2014

Contents

Hepatitis A virus

Index

Hepatitis A virus

Table 2.1 Reported cases of hepatitis A, nationally and by state or jurisdiction ― United States, 2010–2014

Table 2.2 Clinical characteristics of reported cases of hepatitis A* ― United States, 2014

Table 2.3 Number and rate* of hepatitis A-related deaths, by demographic characteristics and year — United States, 2010–2014

Hepatitis B virus

Index

Hepatitis B virus

Table 3.1 Reported cases of acute hepatitis B, nationally and by state or jurisdiction ― United States, 2010-2014

Table 3.2 Clinical characteristics of reported cases of acute hepatitis B* ― United States, 2014

Table 3.3 Number of newly reported case-reports* of confirmed chronic hepatitis B submitted by states and jurisdictions, 2014

Table 3.4. Reported cases of chronic hepatitis B, by demographic characteristics and laboratory tests – Enhanced Viral Hepatitis Surveillance Sites*, 2014

Table 3.5. Number and rate* of hepatitis B-related deaths^†, by demographic characteristics and year – United States, 2010-2014

Hepatitis C virus

Index

Hepatitis C virus

Table 4.1 Reported cases of acute hepatitis C, nationally and by state state and jurisdiction ― United States, 2010-2014

Table 4.2 Clinical characteristics of reported cases of acute hepatitis C* ― United States, 2014

Table 4.3 Number of newly reported case-reports* of confirmed past or present hepatitis C infection submitted by states, 2014

Table 4.4. Reported cases of past or present hepatitis C, by demographic characteristics and laboratory tests – Enhanced Viral Hepatitis Surveillance Sites, 2014

Table 4.5. Number and rate* of hepatitis C-related deaths^†, by demographic characteristics and year – United States, 2010-2014

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Viral Hepatitis Home

Surveillance for Viral Hepatitis – United States, 2014

Contents

Hepatitis A virus

Index

Hepatitis A virus

Table 2.1 Reported cases of hepatitis A, nationally and by state or jurisdiction ― United States, 2010–2014

Hepatitis B virus

Index

Hepatitis B virus

Table 3.1 Reported cases of acute hepatitis B, nationally and by state or jurisdiction ― United States, 2010-2014

Hepatitis C virus

Index

Hepatitis C virus

Table 4.1 Reported cases of acute hepatitis C, nationally and by state state and jurisdiction ― United States, 2010-2014

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Viral Hepatitis Home

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