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Case #301 - June, 2011

A 27-year-old male from Cameroon, who immigrated to the U.S. six years ago, presented to his health care provider with ocular pain and swelling. He told his health care provider that he had an episode of "a worm crawling in his eye" three years prior. Upon examination, the man was found to have a worm-like object below the conjunctiva (Figure A) and it was removed surgically. Figure B shows the object after it was removed; it measured a little over 4 cm. Figure C shows one end of the object at 40x magnification. A blood specimen was also collected and thick smears were prepared and stained with Giemsa. Figures D and E show what was observed in high numbers at 400x magnification. What is your diagnosis? Based on what criteria?

	Case301_A

Figure A

	Case301_B

Figure B

	Case301_C

Figure C

	Case301_D

Figure D

	Case301_E

Figure E

Case Answer

This was a case of loaisis caused by Loa loa. Diagnostic features included:

  • location of the worm in the eye.
  • the presence of irregularly-spaced bosses on the cuticle (Figure C).
  • robust microfilaria with a short head space and a tapered tail with nuclei spaced irregularly to the tip of the tail (Figures D and E).

More on: Loiasis

This case and images were kindly provided by the Florida Lions Ocular Laboratory, Bascom Palmer Eye Institute, Miami, FL.

Images presented in the monthly case studies are from specimens submitted for diagnosis or archiving. On rare occasions, clinical histories given may be partly fictitious.

DPDx is an education resource designed for health professionals and laboratory scientists. For an overview including prevention and control visit www.cdc.gov/parasites/.

  • Page last reviewed: August 24, 2016
  • Page last updated: August 24, 2016
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