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Toxicological Profile for Trichloroethylene (TCE)

Title: Toxicological Profile for Trichloroethylene (TCE)

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.

Type of Dissemination: ISI

Timing of Review (including deferrals): November 2013

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): A draft of this profile will be made available for public comment in 2014.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: Three or fewer

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

1. Post, Gloria

Academic and Professional Credentials

PhD, DABT

Current Position Title

Research Scientist

Organizational Affiliation(s)

Office of Science, New Jersey Department of Environmental Protection, Trenton, NJ

Areas of Expertise, Discipline, Relevant Experiences

human health risk assessment and toxicology research on health effects of environmental contaminants. She currently serves on the EPA Science Advisory Board’s Exposure and Human Health Committee and served on the EPA SAB Trichloroethylene Review Panel. She is a member of the NJ Drinking Water Quality Institute, a legislatively mandated advisory body to NJDEP

Recommended by Scientific/Professional Society or General Public

No

2. Bruckner, James

Academic and Professional Credentials

PhD

Current Position Title

Professor

Organizational Affiliation(s)

Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy and Interdisciplinary Toxicology Program, University of Georgia, Athens, Georgia

Areas of Expertise, Discipline, Relevant Experiences

basic toxicology and pharmacokinetic questions that impact assessments of risks of chemicals to human health; volatile organic chemicals (VOCs) and pesticides: low environmental exposures and cancer risk to humans; drug-chemical interactions; physiologically-based pharmacokinetic models, pyrethroid pesticides and children’s health

Recommended by Scientific/Professional Society or General Public

No

3. Bolt, Hermann

Academic and Professional Credentials

MD, PhD

Current Position Title

Professor Emeritus

Organizational Affiliation(s)

Leibniz Research Centre for Working Environment and Human Factors, Systems toxicology group, Dortmund, Germany

Areas of Expertise, Discipline, Relevant Experiences

Toxicology, Risk assessment, genotoxic carcinogens; occupational standard settings

Recommended by Scientific/Professional Society or General Public

No

Charge to Peer Reviewers: Charge to Peer Reviewers [PDF - 124 KB]

Peer Reviewers’ Comments and CDC/ATSDR’s Response to Peer Reviewers’ Comments: Trichloroethylene [DOC - 312 KB]

The ISI/HISA Dissemination Itself

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