Toxicological Profile for Acrylamide

Title: Toxicological Profile for Acrylamide

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.

Type of Dissemination: ISI

Timing of Review (including deferrals): April 2012

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): ): A draft of this profile was made available for public comment in September, 2009.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3 or fewer

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Charge to Peer Reviewers: DTEM Charge to Peer Reviewers [PDF - 86 KB]

Peer Reviewers:

1. Bolt, Herman, MMD, PhD

Academic and Professional Credentials	Leibniz Research Centre for Working Environment and Human Factors, Systems toxicology group, Dortmund, Germany
Current Position Title	Professor Emeritus
Organizational Affiliation(s)	Current member: American Thoracic Society, American College of Occupational and Environmental Medicine, American College of Chest Physicians
Areas of Expertise, Discipline, Relevant Experiences	Toxicology, Risk assessment, genotoxic carcinogens
Recommended by Scientific/Professional Society or General Public	No

2. Fennell, Timothy R., PhD

Academic and Professional Credentials
Current Position Title	Director, Pharmacology and Toxicology RTI International, Research Triangle Park, NC
Organizational Affiliation(s)
Areas of Expertise, Discipline, Relevant Experiences	Biomarkers, exposure assessment, pharmacokinetics, nanotoxicology, biochemistry
Recommended by Scientific/Professional Society or General Public	No

3. Klaunig, James, PhD

Academic and Professional Credentials
Current Position Title	Professor, Environmental Health Indiana University
Organizational Affiliation(s)
Areas of Expertise, Discipline, Relevant Experiences	Mechanisms of chemically induced toxicology and carcinogenesis with emphasis on human health and genetic and environmental factors affect on human risk.
Recommended by Scientific/Professional Society or General Public	No

Peer Reviewers’ Comments: Acrylamide Summary Report [PDF - 54 KB]

CDC/ATSDR’s Response to Reviewers’ Comments: Acrylamide Formal Disposition [PDF - 290 KB]

The ISI/HISA Dissemination Itself