Plasmodium reichenowi

Plasmodium reichenowi is a malaria parasite that infects chimpanzees.[1]

Plasmodium reichenowi
Scientific classification
(unranked): Diaphoretickes
Clade: TSAR
Clade: SAR
Infrakingdom: Alveolata
Phylum: Apicomplexa
Class: Aconoidasida
Order: Haemospororida
Family: Plasmodiidae
Genus: Plasmodium
Species:
P. reichenowi
Binomial name
Plasmodium reichenowi
Sluiter, Swellengrebel and Ihle, 1922

Taxonomy

Plasmodium reichenowi is classified into the subgenus Laverania.[2] It is a chimpanzee malaria parasite that is evolutionarily related to the human malaria parasite P. falciparum.[3] P. reichenowi and P. falciparum are phylogenetically close to each other.[1] A high-quality reference genome for P. reichenowi was produced from Illumina reads using de novo assembly and post hoc improvement. Excluding the subtelomeres, the genome is almost completely co-linear with P. falciparum and share almost identical gene content emphasizing their recent shared ancestry. The vast majority of these approximately 5,000 ‘core’ genes are common to both parasites, with only three genes present in P. reichenowi that are missing in P. falciparum and only one in P. falciparum that is absent from P. reichenowi.[4]

Hosts

Plasmodium reichenowi normally only infects chimpanzees.[5] A young chimpanzee, followed before and after release to a sanctuary, in a semi-free ranging enclosure located in an equatorial forest, showed fever and strong anaemia associated with a high P. reichenowi infection, shortly after release. The animal recovered from anaemia after several months despite recurrent infection with other Plasmodium species.[2]

Distribution

Chimpanzees live mainly in central and western Africa and this would determine the host range for P. reichenowi.[5]

See also

References
  1. "Plasmodium reichenowi". sanger.ac.uk. Retrieved 21 February 2018.
  2. Herbert, Anaïs; Boundenga, Larson; Meyer, Anne; Diamella, Nancy Moukodoum; Okouga, Alain Prince; Arnathau, Céline; Durand, Patrick; Magnus, Julie; Ngoubangoye, Barthélémy; Willaume, Eric; Ba, Cheikh Tidiane; Rougeron, Virginie; Renaud, François; Ollomo, Benjamin; Prugnolle, Franck (2015). "Malaria-like symptoms associated with a natural Plasmodium reichenowi infection in a chimpanzee". Malaria Journal. 14: 220. doi:10.1186/s12936-015-0743-y. PMC 4502519. PMID 26032157.
  3. Altaf, Lal A.; Goldman, LalIra F.; Campbell, Gary H. (1990). "Primary structure of the 25-kilodalton ookinete antigen from Plasmodium reichenowi". Molecular and Biochemical Parasitology. 43: 143–145. doi:10.1016/0166-6851(90)90139-D.
  4. Otto, Thomas D.; Rayner, Julian C.; Böhme, Ulrike; Pain, Arnab; Spottiswoode, Natasha; Sanders, Mandy; Quail, Michael; Ollomo, Benjamin; Renaud, François; Thomas, Alan W.; Prugnolle, Franck; Conway, David J.; Newbold, Chris; Berriman, Matthew (2014). "Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts". Nature Communications. 5: 4754. doi:10.1038/ncomms5754. PMC 4166903. PMID 25203297.
  5. "Malaria Host Range". malaria.com. Retrieved 21 February 2018.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.