Necrobiosis

Necrobiosis is the physiological death of a cell, and can be caused by conditions such as basophilia, erythema, or a tumor. It is identified both with[1] and without necrosis.

Necrobiosis
Specialty	Pathology

It is associated with necrobiosis lipoidica and granuloma annulare.

Necrobiosis differs from apoptosis, which kills a damaged cell to protect the body from harm.

References

eMedicine/Stedman Medical Dictionary Lookup

External links

Classification	D ICD-10: R68.89 ICD-9-CM: 799.89 MeSH: D017441

"Necrobiosis" at Dorland's Medical Dictionary

Cutaneous keratosis, ulcer, atrophy, and necrobiosis (L82–L94, 700–701.5)

Epidermal thickening

Necrobiosis/granuloma

Necrobiotic/palisading	Granuloma annulare Perforating Generalized Subcutaneous Granuloma annulare in HIV disease Localized granuloma annulare Patch-type granuloma annulare Necrobiosis lipoidica Annular elastolytic giant-cell granuloma Granuloma multiforme Necrobiotic xanthogranuloma Palisaded neutrophilic and granulomatous dermatitis Rheumatoid nodulosis Interstitial granulomatous dermatitis/Interstitial granulomatous drug reaction
Foreign body granuloma	Beryllium granuloma Mercury granuloma Silica granuloma Silicone granuloma Zirconium granuloma Soot tattoo Tattoo Carbon stain
Other/ungrouped	eosinophilic dermatosis Granuloma faciale

Dermis/
localized CTD

Cutaneous lupus erythematosus	chronic: Discoid Panniculitis subacute: Neonatal ungrouped: Chilblain Lupus erythematosus–lichen planus overlap syndrome Tumid Verrucous Rowell's syndrome
Scleroderma/ Morphea	Localized scleroderma Localized morphea Morphea–lichen sclerosus et atrophicus overlap Generalized morphea Atrophoderma of Pasini and Pierini Pansclerotic morphea Morphea profunda Linear scleroderma
Atrophic/ atrophoderma	Lichen sclerosus Anetoderma Schweninger–Buzzi anetoderma Jadassohn–Pellizzari anetoderma Atrophoderma of Pasini and Pierini Acrodermatitis chronica atrophicans Semicircular lipoatrophy Follicular atrophoderma Linear atrophoderma of Moulin
Perforating	Kyrle disease Reactive perforating collagenosis Elastosis perforans serpiginosa Perforating folliculitis Acquired perforating dermatosis
Skin ulcer	Pyoderma gangrenosum
Other	Calcinosis cutis Sclerodactyly Poikiloderma vasculare atrophicans Ainhum/Pseudo-ainhum

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