Large cell neuroendocrine carcinoma of the lung

Large cell neuroendocrine carcinoma of the lung (LCNEC) is a highly malignant neoplasm arising from transformed epithelial cells originating in tissues within the pulmonary tree. It is currently considered to be a subtype of large cell lung carcinoma.

LCNEC is often generically grouped among the non-small cell lung carcinomas.[1]

Variants

The World Health Organization classification of lung tumors[1] recognizes a variant of LCNEC, namely "combined large cell neuroendocrine carcinoma" (c-LCNEC).

References

Travis, William D; Brambilla, Elisabeth; Muller-Hermelink, H Konrad; et al., eds. (2004). Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart (PDF). World Health Organization Classification of Tumours. Lyon: IARC Press. ISBN 978-92-832-2418-1. Retrieved 27 March 2010.

External links

Lung Cancer Home Page. The National Cancer Institute site containing further reading and resources about lung cancer.
. World Health Organization Histological Classification of Lung and Pleural Tumours. 4th Edition.

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[who2004-1] Travis, William D; Brambilla, Elisabeth; Muller-Hermelink, H Konrad; et al., eds. (2004). Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart (PDF). World Health Organization Classification of Tumours. Lyon: IARC Press. ISBN 978-92-832-2418-1. Retrieved 27 March 2010.