Fleischer ring

Fleischer rings are pigmented rings in the peripheral cornea, resulting from iron deposition[1] in basal epithelial cells, in the form of hemosiderin.[2] They are usually yellowish to dark-brown, and may be complete or broken.

Fleischer ring
Differential diagnosiskeratoconus

They are named for Bruno Fleischer.[3]

Fleischer rings are indicative of keratoconus,[4] a degenerative corneal condition that causes the cornea to thin and change to a conic shape.

Confusion with Kayser-Fleischer rings

Some confusion exists between Fleischer rings and Kayser-Fleischer rings. Kayser-Fleischer rings are caused by copper deposits in descemet's membrane of cornea, and are indicative of Wilson's disease, whereas Fleischer rings are caused by iron deposits in basal epithelial cells. One example of a medical condition that can present with Fleischer rings is keratoconus.

See also

References
  1. "Cornea & External Diseases-Keratoconus Fleischer's Ring". Archived from the original on 2009-02-10. Retrieved 2008-10-24.
  2. "Definition: Fleischer's ring from Online Medical Dictionary". Retrieved 2008-10-24.
  3. Fleischer, B (1906). "Über Keratokonus und eigenartige Pigmentbildung in der Kornea". Münchener medizinische Wochenschrift. 53: 625–626.
  4. Hiratsuka Y, Nakayasu K, Kanai A (2000). "Secondary keratoconus with corneal epithelial iron ring similar to Fleischer's ring". Japanese Journal of Ophthalmology. 44 (4): 381–6. doi:10.1016/S0021-5155(00)00179-9. PMID 10974294.
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