Dihydrotachysterol

Dihydrotachysterol (DHT) is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). DHT has a rapid onset of action (2 hours), a shorter half-life, and a greater effect on mineralization of bone salts than does vitamin D.[1]

Dihydrotachysterol
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa682335
ATC code
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.000.611
Chemical and physical data
FormulaC28H46O
Molar mass398.664 g/mol g·mol−1
3D model (JSmol)
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References

  1. Gagnon R, Ogden GW, Just G, Kaye M (April 1974). "Comparison of dihydrotachysterol and 5,6-trans vitamin D3 on intestinal calcium absorption in patients with chronic renal failure". Canadian Journal of Physiology and Pharmacology. 52 (2): 272–4. doi:10.1139/y74-037. PMID 4365509.
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