Clostridium phytofermentans

Clostridium phytofermentans
Scientific classification
Kingdom:	Bacteria
Division:	Firmicutes
Class:	Clostridia
Family:	Clostridiaceae
Genus:	Clostridium
Species:	Cl. phytofermentans
Binomial name
	Clostridium phytofermentans; Warnick et al. 2002

Clostridium phytofermentans [1] is an obligately anaerobic, rod-shaped spore-forming, Gram-positive bacterium in the family Lachnospiraceae. It is a model organism of interest for its ability to rapidly ferment diverse plant polysaccharides [2] including cellulose, hemicellulose, and pectin to ethanol, acetate, and hydrogen. The C. phytofermentans 4.8 Mb genome has been fully sequenced [3], revealing it contains over 170 enzymes in the CAZy database, though one hydrolase appears to be essential for degrading cellulose.[4].

References

Thomas A Warnick, Barbara A Meth, and Susan B Leschine. Clostridium phytofermentans sp. nov., a cellulolytic mesophile from forest soil. Int J Syst Evol Microbiol July 2002 52:1155-60; doi:10.1099/ijs.0.02125-0.
Boutard et al. Functional Diversity of Carbohydrate-Active Enzymes Enabling a Bacterium to Ferment Plant Biomass. PLOS Genetics November 2014; doi:10.1371/journal.pgen.1004773.
Petit et al. Genome and transcriptome of Clostridium phytofermentans, catalyst for the direct conversion of plant feedstocks to fuels. PLOS One June 2015; doi:10.1371/journal.pone.0118285.
Tolonen, Andrew C.; Chilaka, Amanda C.; Church, George M. (1 December 2009). "Targeted gene inactivation in Clostridium phytofermentans shows that cellulose degradation requires the family 9 hydrolase Cphy3367". Molecular Microbiology. 74 (6): 1300–1313. doi:10.1111/j.1365-2958.2009.06890.x. PMC 2810439. PMID 19775243.

"Clostridium phytofermentans ISDg". National Center for Biotechnology Information (NCBI).

External links

Type strain of Clostridium phytofermentans at BacDive - the Bacterial Diversity Metadatabase

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[1] Thomas A Warnick, Barbara A Meth, and Susan B Leschine. Clostridium phytofermentans sp. nov., a cellulolytic mesophile from forest soil. Int J Syst Evol Microbiol July 2002 52:1155-60; doi:10.1099/ijs.0.02125-0.

[2] Boutard et al. Functional Diversity of Carbohydrate-Active Enzymes Enabling a Bacterium to Ferment Plant Biomass. PLOS Genetics November 2014; doi:10.1371/journal.pgen.1004773.

[3] Petit et al. Genome and transcriptome of Clostridium phytofermentans, catalyst for the direct conversion of plant feedstocks to fuels. PLOS One June 2015; doi:10.1371/journal.pone.0118285.

[4] Tolonen, Andrew C.; Chilaka, Amanda C.; Church, George M. (1 December 2009). "Targeted gene inactivation in Clostridium phytofermentans shows that cellulose degradation requires the family 9 hydrolase Cphy3367". Molecular Microbiology. 74 (6): 1300–1313. doi:10.1111/j.1365-2958.2009.06890.x. PMC 2810439. PMID 19775243.