Template:Animal bite antibiotics

Cat and Dog Bites

Coverage for Pasteurella, Strep, and Staph

• Consider for high-risk wounds
  • wounds reaching the level of the muscle/tendon, wounds to the hand, violation of bone or joint capsule, immunocompromised hosts, wounds associated with significant local edema
• Amoxicilin-clavulanate 875mg PO BID x 5-7 days OR
• Doxycycline 100mg PO daily x 14 days if penicillin allergic
• Clindamycin 450mg (5mg/kg) PO q8hrs daily x7 days PLUS
  • Ciprofloxacin 500mg PO q12hrs x 7 days OR
  • TMP/SMX 2DS tabs (5mg/kg) PO q12hrs

Human Bites

All human bites should be strongly considered for antibiotic therapy.

Requires polymicrobial coverage for: S. aureus, Strep Viridans, Bacteroides, Coagulase-neg Staph, Eikenella, Fusobacterium, Cornebacterium, Peptostreptococcus

• Amoxicilin-clavulanate 875mg PO BID x 5-7days OR
• Clindamycin 450mg (5mg/kg) PO q8hrs daily x7 days PLUS
  • Ciprofloxacin 500mg PO q12hrs x 7 days OR
  • TMP/SMX 2DS tabs (5mg/kg) PO q12hrs

Mammalian Bites Severe Infections

• Ampicillin/Sulbactam 3g IV (50mg/kg IV) q 6hrs daily OR
• Cefoxitin 1g IV q8hrs (25mg/kg q6hrs) OR
• Pipericillin/Tazobactam 4.5g IV (80mg/kg IV) q8hrs OR
• Ceftriaxone 1g (50mg/kg IV) once + Metronidazole 500mg IV q8hrs OR
• Clindamycin 600mg IV q8hrs PLUS
  • TMP/SMX 5mg/kg IV q12hrs OR
  • Ciprofloxacin 400mg IV q12hrs OR