Sotalol

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General

Adult Dosing

  • 80mg PO BID

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Indications

  • Suppression of ventricular arrhythmias refractory to other meds
  • Suppression of SVT, a-fib

Contraindications

  • Allergy to class/drug

Adverse Reactions

  • Hypotension, bradycardia
  • Proarrhythmia (esp in patients with hypokalemia)

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:
    • Class II - Nonselective beta-blocker
    • Class III effects (prolongs repol and refractoriness)
  • Onset of action = 2-3hr
  • Duration of action = 24hr

See Also

References