Recommendation Grading System

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Classification

  • Class I - Conditions for which there is evidence and/or general agreement that a given diagnostic evaluation, procedure or treatment is beneficial, useful, and effective.
  • Class II - Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a diagnostic evaluation, procedure or treatment.
  • Class II A - Weight of evidence/opinion is in favor of usefulness/efficacy.
  • Class II B - Usefulness/efficacy is less well established by evidence/opinion.
  • Class III - Conditions for which there is evidence and/or general agreement that a diagnostic evaluation/procedure/treatment is not useful/effective and in some cases may be harmful.

Level of Evidence

  • Level A - Data derived from multiple randomized clinical trials or meta-analyses.
  • Level B -Data derived from a single randomized trial, or nonrandomized studies.
  • Level C - Only consensus opinion of experts, case studies, or standard-of-care.

References

EB Medicine