Nitroprusside

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Background

  • Sodium nitroprusside is primarily used as a potent vasodilator.
  • Works predominantly in arterioles and venules as a result of its breakdown to nitric oxide (NO).[1]
  • Nitric oxide reduces both total peripheral resistance and venous return, thus decreasing both preload and afterload
  • Thiocyanate level when checking for toxicity

Adult Dosing

Pediatric Dosing

Contraindications

Indications

Mechanism of Action

Potent arteriolar dilation from its active metabolite, nitric oxide (NO).

Adverse Drug Reactions

Kinetics

See Also

  1. "nitroprusside sodium (Rx) - Nipride, Nitropress, more..". Medscape Reference. WebMD. Retrieved 20 November 2013.