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Famiciclovir
From WikEM
Contents
Administration
- Type: Antiviral
- Dosage Forms:
- Routes of Administration: Oral
- Common Trade Names: Famvir
Adult Dosing
- 150-1000mg PO BID
Pediatric Dosing
Safety/efficacy not established
Special Populations
- Pregnancy Rating: B
- Lactation risk: Infant risk cannot be ruled out
- Renal dosing: reduced dose
- Hepatic dosing: no adjustment for mild-moderate impairment
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Neutropenia
- Elevated AST/ALT
Common
- Nausea/vomiting, diarrhea
- Headache
- Fatigue
Pharmacology
- Half-life: 2.3h
- Metabolism: Hepatic
- Excretion: Mostly renal
Mechanism of Action
- Inhibits viral DNA synthesis
