Esophagitis

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Background

  • Inflammation of the esophagus

Clinical Features

  • Odynophagia and/or dysphagia
    • Commonly causes dehydration
  • Chest pain
  • Nausea
  • Dyspepsia

Differential Diagnosis

Esophagitis Types

  • Inflammatory
    • GERD
    • Pill esophagitis (NSAIDs, antibiotics)
    • Allergy (esoninophillic)
  • Infectious Mainly seen in pts w/ immunosuppression (HIV/AIDS, cancer, steroids)
    • Esophageal candidiasis: often an AIDS defining lesion
    • HSV, CMV esophagitis, aphthous ulceration
  • Pill esophagitis common culprits:
    • Doxycycline
    • Tetracycline
    • Clindamycin
    • NSAIDs
    • ASA
    • Bisphosphonates
    • Ferrous sulfate
    • Potassium chloride
    • Ascorbic acid

Evaluation

Work-Up

  • CBC
  • CMP
  • Consider HIV workup if unknown causation, risk factors

Evaluation

  • Generally clinical diagnosis in ED (requires EGD for conclusive diagnosis)

Management

  • PPI for GERD-induced esophagitis
  • IV Fluids for dehydration
  • Candidal Infection[1]
    • 400mg PO loading dose x1
    • 100-400mg PO for 14-21 days

Disposition

  • Admit if unable to tolerate PO or if underlying immunosuppression (e.g. HIV)

See Also

References

  1. Hess JM, Lowell MJ. Esophagus, stomach, and duodenum, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 7. St. Louis, Mosby, Inc., 2010, Ch. 89:1170-1185.