Cryoprecipitate transfusion

Features

1. Cold insoluble protein fraction of FFP
2. Contains: fibrinogen, vWF, and factor VIII
3. 1 bag (10ml) has 50-500 units of factor 8 activity

Indications

1. Bleeding with fibrinogen level of <100 milligrams/dL
2. Dysfibrinogenemia
3. Bleeding in vWD that is unresponsive to DDAVP and Factor VIII is unavailable (can also use Humate-P, FFP does not work well)

Dose

1 unit/5kg (usually 10 units are given at a time)

• Will raise fibrinogen level by 75

See Also

• Transfusions

References

Authors

Ross Donaldson