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Camphor toxicity
From WikEM
Background
- Common topical agent for pain relief, wart removal, osteoarthritis, cold sores
- FDA limits over the counter preparations to 11%[1]
- Highly lipophilic, widely and rapidly distributed, symptom onset 5-15 minutes
- CNS Stimulant when ingested
Clinical Features
- Nausea, vomiting, abdominal pain
- Oral burning, headache
- Vertigo, confusion, agitation
- Seizure, respiratory depression, coma
- Hepatitis and liver failure
Management
- Aggressive supportive care[2]
- Benzodiazepines for seizure
- Intubation and mechanical ventilation as needed
- Charcoal not likely effective
