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Bacitracin
From WikEM
Contents
Administration
- Type: Topical antibiotic
- Dosage Forms: ointment
- Routes of Administration: topical, IM
- Common Trade Names:
Adult Dosing
- Apply to wound 2-5 times per day
Pediatric Dosing
- Apply to wound 2-5 times per day
- Staph pneumonia/empyema known to be susceptible to bacitracin: 900-1000 units/kg/day IM in 2 to 3 divided doses
Special Populations
- Pregnancy Rating: C
- Lactation risk: Infant risk minimal
- Renal: no adjustment
- Hepatic: No adjustment
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Renal toxicity (IM only)
Common
- Contact dermatitis
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Interferes with cell wall peptidoglycan activity
- Active against staph
