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Antifungal
From WikEM
Contents
Classes
Polyene anti fungals
Imidazole, triazole, and thiazole antifungals
Imidazoles
- Bifonazole
- Butoconazole
- Clotrimazole
- Econazole
- Fenticonazole
- Isoconazole
- Ketoconazole
- Luliconazole
- Miconazole
- Omoconazole
- Oxiconazole
- Sertaconazole
- Sulconazole
- Tioconazole
Triazoles
- Albaconazole
- Efinaconazole
- Epoxiconazole
- Fluconazole
- Isavuconazole
- Itraconazole
- Posaconazole
- Propiconazole
- Ravuconazole
- Terconazole
- Voriconazole
Thiazoles
Allylamines
Inhibit squalene epoxidase, an enzyme required for ergosterol synthesis.
Echinocandins
May be used for systemic fungal infections in immunocompromised patients; inhibit the synthesis of glucan in the cell wall via the enzyme Beta (1-3) glucan synthase; are poorly absorbed when administered orally
