Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content
NIOSH

NICOTINAMIDE

ICSC: 1703

Pyridine-3-carboxylamide
3-Pyridinecarboxamide
Niacinamide
C6H6N2O
Molecular mass: 122.1
ICSC # 1703 		CAS # 98-92-0
RTECS # QS3675000
April 08, 2008 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.

Water spray, foam, powder, carbon dioxide.
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
PREVENT DISPERSION OF DUST!

•INHALATION Cough.
Avoid inhalation of dust.
Fresh air, rest.
•SKIN
Protective gloves.
Rinse skin with plenty of water or shower.
•EYES Redness. Pain.
Safety goggles
Rinse with plenty of water (remove contact lenses if easily possible).
•INGESTION
Do not eat, drink, or smoke during work.
Rinse mouth. Give one or two glasses of water to drink.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Personal protection: particulate filter adapted to the airborne concentration of the substance. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.
Separated from oxidants.

Signal: Warning
Causes eye irritation
ICSC: 1703 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

NICOTINAMIDE

ICSC: 1703

I

M

P

O

R

T

A

N

T


D

A

T

A

PHYSICAL STATE; APPEARANCE:
WHITE CRYSTALLINE POWDER.

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
On combustion, forms toxic gases, including nitrogen oxides. Reacts with oxidants.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK not established.


ROUTES OF EXPOSURE:


INHALATION RISK:
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Sublimation
Melting point: 127-131°C
Density: 1.4
g/cm3
Solubility in water, g/100 ml at 20°C: 100
(very good)
Vapour pressure, kPa at 35°C: 3.1
Relative vapour density (air = 1): 4.2
Flash point: 182°C
Auto-ignition temperature: 480°C
Octanol/water partition coefficient as log Pow: -0.38

ENVIRONMENTAL
DATA


N O T E S

ADDITIONAL INFORMATION



ICSC: 1703 NICOTINAMIDE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
Top