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NIOSH

NICOTINIC ACID

ICSC: 1702

3-Pyridinecarboxylic acid
3-Carboxypyridine
Pyridine-beta-carboxylic
Niacin
C6H5NO2/HOOC5H4N
Molecular mass: 123.1
ICSC # 1702 		CAS # 59-67-6
RTECS # QT0525000
April 08, 2008 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Water spray, foam, powder, carbon dioxide
EXPLOSION Finely dispersed particles form explosive mixtures in air.
Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE
PREVENT DISPERSION OF DUST!

•INHALATION Cough.
Avoid inhalation of dust.
Fresh air, rest.
•SKIN
Protective gloves.
Rinse skin with plenty of water or shower.
•EYES Redness.
Safety goggles
Rinse with plenty of water (remove contact lenses if easily possible).
•INGESTION Flushing of the face.
Do not eat, drink, or smoke during work.
Rinse mouth. Give one or two glasses of water to drink.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Personal protection: particulate filter adapted to the airborne concentration of the substance. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment.
Store in an area without drain or sewer access. Separated from strong acids, bases and oxidants .

Signal: Warning
Causes eye irritation
Harmful to aquatic life
ICSC: 1702 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

NICOTINIC ACID

ICSC: 1702

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PHYSICAL STATE; APPEARANCE:
WHITE CRYSTALS OR CRYSTALLINE POWDER.

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
On combustion, forms toxic gases, including nitrogen oxides. Reacts with oxidants , strong acids and bases .

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK not established.


ROUTES OF EXPOSURE:


INHALATION RISK:
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is mildly irritating to the eyes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Melting point: 236.6°C
Density: 1.5
g/cm3
Solubility in water, g/100 ml at 20°C: 1.8
(moderate)
Flashpoint: 193°C c.c.
Auto-ignition temperature: 580°C
Explosive limits, vol% in air: 25 - ?
Octanol/water partition coefficient as log Pow: -2.43

ENVIRONMENTAL
DATA

The substance is harmful to aquatic organisms.

N O T E S

ADDITIONAL INFORMATION



ICSC: 1702 NICOTINIC ACID
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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