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NIOSH

ISOBUTYLAMINE

ICSC: 1253

2-Methylpropylamine
2-Methyl-1-propanamine
1-Amino-2-methylpropane
C4H11N / (CH3)2CHCH2NH2
Molecular mass: 73.1
ICSC # 1253 		CAS # 78-81-9
RTECS # NP9900000
UN # 1214
April 20, 2005 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames, NO sparks, and NO smoking.
Powder, alcohol-resistant foam, water spray, carbon dioxide.
EXPLOSION Vapour/air mixtures are explosive.
Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools.
In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
AVOID ALL CONTACT!
IN ALL CASES CONSULT A DOCTOR!
•INHALATION Burning sensation. Cough. Shortness of breath. Laboured breathing. Symptoms may be delayed (see Notes).
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
•SKIN Pain. Redness. Skin burns.
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.
•EYES Redness. Pain. Severe deep burns.
Face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Abdominal pain. Burning sensation. Shock or collapse.
Do not eat, drink, or smoke during work.
Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking liquid in sealable containers. Cautiously neutralize spilled liquid. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Then wash away with plenty of water.
Fireproof. Separated from strong oxidants, strong acids, food and feedstuffs .
Unbreakable packaging; put breakable packaging into closed unbreakable container.
UN Hazard Class: 3
UN Subsidiary Risks: 8
UN Packing Group: II
ICSC: 1253 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

ISOBUTYLAMINE

ICSC: 1253

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PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:
The vapour is heavier than air and may travel along the ground; distant ignition possible.

CHEMICAL DANGERS:
The substance decomposes on burning producing toxic gases including nitrogen oxides . The solution in water is a medium strong base. Reacts violently with acids and oxidants .

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK: 5 ppm, 15 mg/m3; skin absorption (H);
Peak limitation category: I(2); Pregnancy risk group: IIc;
(DFG 2004).


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

INHALATION RISK:
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. Inhalation of the substance may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Boiling point: 68-69°C
Melting point: -85°C
Relative density (water = 1): 0.72
Solubility in water: miscible
Vapour pressure, kPa at 18.8°C: 13.3
Relative vapour density (air = 1): 2.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.2
Flash point: -9.0°C c.c.
Auto-ignition temperature: 378°C
Explosive limits, vol% in air: 3.4-9
Octanol/water partition coefficient as log Pow: 0.73

ENVIRONMENTAL
DATA


N O T E S

The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
Transport Emergency Card: TEC (R)-30GFC-II

NFPA Code: H3; F3; R0

ADDITIONAL INFORMATION



ICSC: 1253 ISOBUTYLAMINE
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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