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NIOSH

T.E.P.P.

ICSC: 1158

Tetraethyl pyrophosphate
Diphosphoric acid, tetraethyl ester
Tetraethyl diphosphate
C8H20O7P2 / (C2H5O)2POOPO(OC2H5)2
Molecular mass: 290.2
ICSC # 1158 		CAS # 107-49-3
RTECS # UX6825000
UN # 3018
EC # 015-025-00-2
April 22, 1994 Validated

TYPES OF HAZARD/ EXPOSURE

ACUTE HAZARDS/ SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
NO open flames.
Powder, alcohol-resistant foam, water in large amounts, carbon dioxide.
EXPLOSION Risk of fire and explosion.

In case of fire: keep drums, etc., cool by spraying with water.
EXPOSURE
AVOID ALL CONTACT! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!
IN ALL CASES CONSULT A DOCTOR!
•INHALATION Cough. Nausea. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Laboured breathing. Dizziness. Ataxia. Convulsions. Vomiting. Unconsciousness.
Ventilation, local exhaust, or breathing protection.
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
•SKIN MAY BE ABSORBED! Skin burns. Pain. (Further see Inhalation).
Protective gloves. Protective clothing.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
•EYES MAY BE ABSORBED! Redness. Pain. Pupillary constriction. Blurred vision. Headache.
Face shield or eye protection in combination with breathing protection.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION Abdominal cramps. Diarrhoea. Nausea. Vomiting. (Further see Inhalation).
Do not eat, drink, or smoke during work. Wash hands before eating.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Do NOT induce vomiting. Rest. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment.
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs . Dry. Keep in a well-ventilated room.
Do not transport with food and feedstuffs.
Marine pollutant.
T+ symbol
N symbol
R: 27/28-50
S: 1/2-36/37/39-38-45-61
UN Hazard Class: 6.1
UN Packing Group: I
ICSC: 1158 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

T.E.P.P.

ICSC: 1158

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PHYSICAL STATE; APPEARANCE:
COLOURLESS HYGROSCOPIC LIQUID.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
The substance decomposes on heating producing above 150°C flammable gas, ethylene and toxic fumes including phosphorus oxides . Attacks some forms of plastic, rubber and coatings, corrosive to most metals.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 0.05 mg/m3 as TWA; (skin); BEI issued; (ACGIH 2004).
MAK: 0.005 ppm, 0.06 mg/m3;
Peak limitation category: II(2);
skin absorption (H); (DFG 2004).
OSHA PEL: TWA 0.05 mg/m3 skin
NIOSH REL: TWA 0.05 mg/m3 skin
NIOSH IDLH: 5 mg/m3 See: 107493


ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin, by ingestion and and through the eyes.

INHALATION RISK:
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C, on spraying much faster.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes and the skin . The substance may cause effects on the central nervous system , resulting in convulsions, respiratory failure and death. Cholinesterase inhibitor. The effects may be delayed. Medical observation is indicated. See Notes.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms.

PHYSICAL
PROPERTIES

Decomposes below boiling point at 170°C
Melting point: see Notes
Relative density (water = 1): 1.2
Solubility in water: good
Vapour pressure, Pa at 20°C: 2
Relative vapour density (air = 1): 10
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: see Notes
Auto-ignition temperature: see Notes
Octanol/water partition coefficient as log Pow: 2.94

ENVIRONMENTAL
DATA

This substance may be hazardous to the environment; special attention should be given to mammals, birds, honey bees and aquatic organisms.

N O T E S

Melting point: sets to glassy state below 0°C. Auto-ignition temperature is unknown in literature. The substance is combustible but no flash point is available in literature. Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Bladan, Fosnex, Gy-Tet 40, HETP, Hexaethyltetraphosphate, Killex, Kilmite, Lethalaire, Licophosphate, Nifos T, Pyfos, Pyro-Phos, Teep, Tetradusto 100, Tetron, Tetraspa and Vapotone are trade names. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
Transport Emergency Card: TEC (R)-61GT6-I

ADDITIONAL INFORMATION



ICSC: 1158 T.E.P.P.
(C) IPCS, CEC, 1994
IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.
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